Chronic non-cancer pain in adolescents: a narrative review

Abstract Introduction Chronic pain is defined as a pain lasting more than 3-6 months. It is estimated that 25% of the pediatric population may experience some kind of pain in this context. Adolescence, corresponding to a particular period of development, seems to present the ideal territory for the appearance of maladaptive mechanisms that can trigger episodes of persistent or recurrent pain. Methods A narrative review, in the PubMed/Medline database, in order to synthetize the available evidence in the approach to chronic pain in adolescents, highlighting its etiology, pathophysiology, diagnosis, and treatment. Results Pain is seen as a result from the interaction of biological, psychological, individual, social, and environmental factors. Headache, abdominal pain, and musculoskeletal pain are frequent causes of chronic pain in adolescents. Pain not only has implications on adolescents, but also on family, society, and how they interact. It has implications on daily activities, physical capacity, school performance, and sleep, and is associated with psychiatric comorbidities, such as anxiety and depression. The therapeutic approach of pain must be multimodal and multidisciplinary, involving adolescents, their families, and environment, using pharmacological and non-pharmacological strategies. Discussion and conclusion The acknowledgment, prevention, diagnosis, and treatment of chronic pain in adolescent patients seem not to be ideal. The development of evidence-based forms of treatment, and the training of health professionals at all levels of care are essential for the diagnosis, treatment, and early referral of these patients.

Preditores de videogames para dispositivos móveis na dor do músculo esquelético entre estudantes universitários em Selangor, Malásia / Predictors of Mobile Video Gaming on Musculoskeletal Pain among University Students in Selangor, Malaysia

OBJETIVOS: Jogar videogames em dispositivos móveis tem aumentado rapidamente entre estudantes universitários, mais do que antes da pandemia do COVID-19. Isso é muito preocupante, pois pode desencadear vários problemas, como dores musculoesqueléticas e distúrbios de jogo. Vários estudos semelhantes foram realizados em vários países, mas limitados na Malásia. O presente estudo tem como objetivo investigar o efeito dos videogames móveis na dor musculoesquelética entre estudantes universitários em Selangor, Malásia. PARTICIPANTES E MÉTODOS: Este estudo foi conduzido online usando um questionário online auto-relatado por meio do Formulário Google e enviado a estudantes universitários em Selangor, Malásia. O vício em jogos dos participantes foi medido por meio do questionário Ten Item Internet Gaming Disorder test (IGDT-10) e a prevalência de dor musculoesquelética foi avaliada pelo Modified Nordic Musculoskeletal Questionnaire (MNMQ). RESULTADOS: A prevalência de Transtorno de Jogos na Internet entre estudantes universitários em Selangor, Malásia, é de 1,8% (n = 3). A região do pescoço (74,2%) foi a região do corpo mais comumente relatada com dor musculoesquelética, seguida pela região dos ombros (60,7%), região lombar (55,8%) e região superior das costas (50,9%). Houve associação significativa entre a posição corporal durante o videogame móvel (p = 0,002) e a dor musculoesquelética na região lombar. CONCLUSÃO: De acordo com os resultados deste estudo, a prevalência de Transtorno de Jogos na Internet entre estudantes universitários era baixa e não viciados em jogos no bloqueio Covid-19. Também descobrimos que os participantes que se sentaram enquanto jogavam videogames para celular tinham maior probabilidade de desenvolver dor lombar.

INTRODUCTION: Mobile video gaming among university students has increased rapidly, more than before the COVID-19 pandemic. This is very concerning as this could spark various problems, such as musculoskeletal pain and gaming disorders. OBJECTIVES: The present study is to identify the predictors of mobile video gaming on musculoskeletal pain among university students in Selangor, Malaysia. PARTICIPANTS AND METHODS: This study was conducted online using a self-reported online questionnaire via Google Form and sent to university students in Selangor, Malaysia. Participants' gaming addiction was measured using the Ten Item Internet Gaming Disorder Test (IGDT-10) questionnaire, and the prevalence of musculoskeletal pain was assessed by the Modified Nordic Musculoskeletal Questionnaire (MNMQ). The data was analyzed using SPSS version 25. A descriptive and binomial linear regression test was used to predict the variables. The statistical significance was set at p < 0.05, and odds ratios were calculated with confidence intervals of 95%. RESULTS: The prevalence of Internet Gaming Disorder among university students in Selangor, Malaysia is 1.8% (n=3). The neck region (74.2%) was the most commonly reported body region with musculoskeletal pain, followed by the shoulder region (60.7 %), lower back region (55.8 %), and upper back region (50.9 %). The body position was the only predictor of mobile video gaming with musculoskeletal pain (p = 0.002) in the lower back region. CONCLUSION: According to the findings of this study, the prevalence of Internet Gaming Disorder (IGD) among university students was low and not addicted to gaming in the Covid-19 lockdown. We also found that participants who sat while playing mobile video games were more likely to develop low back pain. However, one of the limiting factors could be prolonged sitting in virtual classes during the lockdown, which causes low back pain.

Manifestaciones Musculoesqueléticas de Neoplasias en Pediatría a propósito de tres Casos Clínicos / Musculoskeletal manifestations of neoplasms in children: three reported cases

Introducción: El dolor musculoesquelético (ME) es un motivo de consulta común en la infancia originado en su mayoría por causas banales. Entre las causas menos frecuentes encontramos las patologías reumatológicas y neoplásicas. Se presentan tres casos clínicos que debutaron con artritis o artralgia en los cuales el diagnóstico final fue neoplásico. Casos clínicos: el primer caso fue una Leucemia Linfoblástica Aguda (LLA) de alto riesgo, el segundo caso fue un sarcoma de Ewing y el tercer caso fue una LLA común. Dos de los casos tuvieron evolución desfavorable con fallecimiento. Revisión de la literatura: Se describen hallazgos que deben hacer sospechar una causa neoplásica tales como el dolor ME desproporcionado, alteraciones en el hemograma, velocidad de eritrosedimentación globular y lactato deshidrogenasa elevados, y radiografía con alteraciones sugerentes. Conclusiones: Frente a un dolor ME en el niño se debe tener presente las causas neoplásicas a pesar de su baja frecuencia dado su mal pronóstico.

Introduction: Musculoskeletal (MS) pain is a common complaint in childhood, usually caused by trivial ailments. Among less frequent causes we may find rheumatological and neoplastic pathologies. We present 3 clinical cases in which a rheumatological cause was initially suspected, as they started out with arthritis or arthralgia, but where the diagnosis was finally a neoplasm. Clinical cases: the first case was a high-risk Acute Lymphoblastic Leukemia (ALL), the second case was a Ewing's sarcoma, and the third case was a common ALL. Two of the cases had unfavourable outcomes and passed away. Literature review: Findings that should make us suspect neoplastic causes are disproportionate MS pain, altered hemogram, elevated erythrocyte sedimentation rate and lactate dehydrogenase, and an x ray with suggestive alterations. Conclusions: When faced with MS pain in children, neoplastic causes must be taken into account despite their low frequency given the poor prognosis associated with the diagnosis.

Análise do equilíbrio postural estático e da intensidade das dores musculoesqueléticas após o uso de palmilhas proprioceptivas por militares do serviço ostensivo / Análisis del equilibrio postural estático y de la intensidad de los dolores musculoesqueléticas después del uso de plantillas propioceptivas por militares del servicio ostensivo / Analysis of static postural balance and of intensity of musculoskeletal pains after the use of proprioceptive insoles by ostensive service militaries

RESUMO Para a manutenção do equilíbrio, o organismo utiliza os sistemas visuais, vestibulares e proprioceptivos, que enviam informações para o sistema nervoso central acerca das condições do corpo com o objetivo de estabilizá-lo. Este estudo avaliou o efeito das palmilhas proprioceptivas sobre o equilíbrio postural estático e as dores musculoesqueléticas após dois meses de uso, por meio de uma pesquisa analítica longitudinal com 15 militares saudáveis do sexo masculino com média de idade de 34±7,5 anos. Eles foram submetidos à avaliação do equilíbrio por meio da plataforma Medicapteurs® e pelo protocolo CNT. Não houve diferença estatística para os desvios do corpo e velocidade do centro de pressão. A pressão plantar teve mudança estatisticamente significante para o pé esquerdo e o pé direito correspondendo a p=0,0001 e p=0,0007, respectivamente. Houve redução das médias de dores nos joelhos, pés e calcanhares e diminuição significativa da dor lombar, com p=0,0180. O equilíbrio estático não foi alterado significativamente com o uso das palmilhas proprioceptivas pelos militares, contudo elas proporcionaram melhor redistribuição das pressões plantares e parecem atenuar as dores musculoesqueléticas das extremidades inferiores. Por isso as palmilhas podem ser consideradas para esse grupo uma terapêutica de prevenção contra lesões relacionadas à sua atividade laboral.

RESUMEN Para mantener el equilibrio el cuerpo utiliza los sistemas visuales, vestibulares y propioceptivos, que envían información al sistema nervioso central sobre las condiciones del cuerpo para estabilizarlo. Este estudio evaluó el efecto de las plantillas propioceptivas sobre el equilibrio postural estático y los dolores musculoesqueléticas después de dos meses de uso, a través de una investigación analítica longitudinal con 15 soldados sanos con una edad media de 34±7.5 años. Ellos fueron sometidos a evaluación de equilibrio a través de la plataforma Medicapteurs® y por el protocolo CNT. No hubo diferencia estadística para las desviaciones del cuerpo y para la velocidad del centro de presión. La presión plantar tuvo un cambio estadísticamente significativo para el pie izquierdo y el pie derecho correspondiente a p=0.0001 y p=0.0007, respectivamente. Hubo una reducción en las promedio de los dolores en las rodillas, pies y talones y una disminución significativa en el dolor lumbar, con p=0.0180. El equilibrio estático no se modificó significativamente con el uso de plantillas propioceptivas por los militares, sin embargo, proporcionaron una mejor redistribución de las presiones plantares y parecen ablandar los dolores musculoesqueléticas en las extremidades inferiores. Por lo tanto las plantillas pueden considerarse para ese grupo como una terapia de prevención contra lesiones relacionadas con su actividad laboral.

ABSTRACT To maintain the balance, the body uses visual, vestibular and proprioceptive systems, which send information to the central nervous system about the body's conditions in order to stabilize it. This study evaluated the effect of proprioceptive insoles on static postural balance and musculoskeletal pains after two months of use, through a longitudinal analytical study with 15 healthy male soldiers with a mean age of 34±7.5 years. They were subjected to balance evaluation through the Medicapteurs® platform and by CNT protocol. There was no statistical difference for the deviations of the body and speed of the center of pressure. Plantar pressure had a statistically significant change for the left and the right feet, corresponding to p=0.0001 and p=0.0007, respectively. There was a reduction in the mean values of the pains in the knees, feet and heels and a significant decrease in lumbar spine pain, with p=0.0180. The static balance was not significantly altered with the use of proprioceptive insoles by the militaries; however, these insoles provided a better redistribution of plantar pressures and seem to attenuate the musculoskeletal pains of the lower extremities. Therefore, insoles can be considered as a prevention therapy against injuries for this group related to their work activity.

Síndrome de Ehlers-Danlos hipermóvel: um relato de caso / Hypermobile Ehlers-Danlos syndrome: a case report

A síndrome de Ehlers-Danlos é estabelecida por distúrbios hereditários do tecido conjuntivo que tem como manifestações principais a hipermobilidade articular, a hiperextensibilidade da pele e a fragilidade de tecidos, como articulações, ligamentos, pele, vasos sanguíneos e órgãos internos. São reconhecidos 13 subtipos, de acordo com Classificação Internacional de 2017. Dentre estes, abordamos o hipermóvel, cujo diagnóstico é eminentemente clínico, com manifestações sistêmicas distintas. Esse artigo refere-se ao caso de uma paciente diagnosticada com síndrome de Ehlers-Danlos hipermóvel, tendo como intuito a atualização acerca dos novos critérios diagnósticos, assim como o diagnóstico precoce de tal raropatia.

Ehlers-Danlos syndrome is established through hereditary disorders of connective tissue, and has as its manifestations: joint hypermobility, skin hyperextensibility, and fragility of tissues such as joints, ligaments, skin, blood vessels, and internal organs. Thirteen subtypes have been recognized according to the 2017 International Classification. Among these, the hypermobile type, the diagnosis of which is eminently clinical, with distinct systemic manifestations, will be addressed. This article refers to the case of a patient diagnosed with hypermobile Ehlers-Danlos syndrome, with the objective of updating the new diagnostic criteria, as well as the early diagnosis of such a rare disease.

Musculoskeletal pain and musculoskeletal syndromes in adolescents are related to electronic devices / Dor musculoesquelética e síndromes musculoesqueléticas em adolescentes relacionadas a dispositivos eletrônicos

Abstract Objective: To evaluate television and simultaneous electronic devices use in adolescents with musculoskeletal pain and musculoskeletal pain syndromes. Methods: A cross-sectional study was performed in 299 healthy adolescents of a private school. All students completed a self-administered questionnaire, including: demographic data, physical activities, musculoskeletal pain symptoms, and use of simultaneous television/electronic devices (computer, internet, electronic games, and cell phones). Seven musculoskeletal pain syndromes were also evaluated: juvenile fibromyalgia, benign joint hypermobility syndrome, myofascial syndrome, tendinitis, bursitis, epicondylitis, and complex regional pain syndrome. Results: Inter-rater agreement between pretest and retest was 0.83. Musculoskeletal pain and musculoskeletal pain syndrome were found in 183/299 (61%) and 60/183 (33%), respectively. The median age (15 [10-18] vs. 14 [10-18] years, p = 0.032) and years of education (10 [5-12] vs. 9 [5-12] years, p = 0.011) were significantly higher in adolescents with musculoskeletal pain when compared with those without this condition. The frequencies of female gender (59% vs. 47%, p = 0.019), cell phone use (93% vs. 81%, p = 0.003), and simultaneous use of at least two electronic devices (80% vs. 67%, p = 0.011) were significantly higher in the former group. Further comparisons between adolescents with and without musculoskeletal pain syndromes revealed that the frequency of female gender was significantly higher in the former group (75% vs. 25%, p = 0.002), and with a significantly reduced median of weekends/holidays electronic games use (1.5 [0-10] vs. 3 [0-17] h/day, p = 0.006). Conclusions: A high prevalence of musculoskeletal pain/syndromes was observed in female adolescents. Musculoskeletal pain was mostly reported at a median age of 15 years, and students used at least two electronic devices. Reduced use of electronic games was associated with musculoskeletal pain syndromes.

Resumo Objetivo: Avaliar o uso de televisão e dispositivos eletrônicos em adolescentes com dor e síndromes musculoesqueléticas. Métodos: Foi feito um estudo transversal com 299 adolescentes saudáveis de uma escola particular. Todos os alunos responderam a um questionário autoaplicável, que incluiu perguntas sobre: dados demográficos, prática de atividade física, sintomas de dor musculoesquelética e o uso de televisão/dispositivos eletrônicos (computador, internet, jogos eletrônicos e celular). Sete síndromes musculoesqueléticas foram avaliadas: fibromialgia juvenil, síndrome de hipermobilidade articular benigna, síndrome miofascial, tendinite, bursite, epicondilite e síndrome de dor regional complexa. Resultados: A concordância entre o pré-teste e reteste foi de 0,83. Dor musculoesquelética e síndromes musculoesqueléticas foram encontradas em 183/299 (61%) e 60/183 (33%), respectivamente. As medianas de idade [15 (10-18) versus 14 (10-18) anos, p = 0,032] e de anos de escolaridade [10 (5-12) vs. 9 (5-12) anos, p = 0,010] foram significantemente maiores em adolescentes com dor musculoesquelética em comparação com aqueles sem essa condição. As frequências do sexo feminino (59% versus 47% p = 0,019), uso do telefone celular (93% contra 81%, p = 0,003) e do uso simultâneo de pelo menos dois dispositivos eletrônicos (80% vs. 67%, p = 0,011) foram significantemente maiores no grupo de adolescentes com dor musculoesquelética. Comparações adicionais entre os adolescentes com e sem síndromes musculoesqueléticas revelaram que a frequência do sexo feminino foi significantemente maior no primeiro grupo (75% versus 25%, p = 0,002) e com mediana significantemente reduzida de horas de jogos eletrônicos nos fins de semana e feriados [1,5 (0-10) vs. 3 (0-17) horas/dia, p = 0,006]. Conclusões: Uma alta prevalência de dor/síndromes musculoesqueléticas foi observada em adolescentes do sexo feminino. A dor musculoesquelética foi predominantemente relatada entre alunos com mediana de idade de 15 anos e que usavam pelo menos dois dispositivos eletrônicos simultaneamente. O uso reduzido de jogos eletrônicos foi associado à presença de síndromes musculoesqueléticas.

Dor musculoesquelética em motoristas e cobradores de ônibus da Região Metropolitana de Belo Horizonte, Brasil / Musculoskeletal pain among bus drivers and fare collectors in the Metropolitan Region of Belo Horizonte, Brazil

Resumo A dor musculoesquelética em profissionais do setor de transporte tem sido relacionada às condições de trabalho. Objetivou-se estimar a prevalência de dor cervical e sua relação com a dor em outros sítios (braços, mãos e ombros). Verificou-se a associação entre dor no pescoço, relacionada ou não à dor nos outros sítios, com os fatores ocupacionais. Estudo transversal, descritivo e analítico. Foram entrevistados 799 motoristas e 708 cobradores de ônibus da Região Metropolitana de Belo Horizonte, Brasil. Para o desfecho foi considerada a resposta sobre a existência de dor por sítio anatômico. A prevalência de dor musculoesquelética no pescoço foi de 16,3%. Para ombros, braços e mãos foram 15,4%, 13,3% e 6,3%, respectivamente. Aqueles com dor no pescoço apresentaram maiores prevalências de dores nas demais áreas estudadas. Os fatores associados à dor musculoesquelética foram sexo feminino, relato de incapacidade, percepção de ameaça a segurança, vibração, ruído elevado ou insuportável e adoção de postura desconfortável. Os resultados indicaram a elaboração de pistas para transformação do ambiente de trabalho, de maneira a contribuir para a promoção da saúde dos trabalhadores.

Abstract Musculoskeletal pain among professionals in the transport sector has been linked to working conditions. The scope of this study was to assess the prevalence of cervical musculoskeletal pain and its relation to pain in other areas (arms, hands and shoulders). The association between neck pain, related to pain in other areas or otherwise, was checked against occupational factors. A cross-sectional, descriptive and analytical study was conducted with 799 bus drivers and 708 fare collectors of the Metropolitan Region of Belo Horizonte, Brazil. The outcome was characterized according to the positive answer to the question about musculoskeletal pain in the anatomical areas studied. The prevalence of neck pain in the sample was highest at 16.3%, followed by pain in the shoulders 15.4%, arms 13.3% and hands 6.3%. The factors associated with musculoskeletal pain in the sample were being female, complaints of disability, perception of threat to safety, vibration, excessive or unbearable noise and sitting in an uncomfortable posture. The results provide clues to transformation of the workplace, thereby contributing to the enhancement of occupational health.

Dolor en adolescentes y sus factores de riesgo: estudio de casos y controles / Pain in adolescents and its risk factors: A case-control study

Introducción. Los síndromes dolorosos más comunes (cefalea, dolor abdominal y dolor musculoesquelético) aparecen o empeoran durante la adolescencia, y son frecuente motivo de consulta. Objetivo. Evaluar la asociación de edad, sexo, obesidad, desarrollo puberal, nivel de escolarización, trabajo y constitución familiar con la consulta por dolor en adolescentes. Población y métodos. Estudio de casos y controles realizado entre el 1/2/14 y el 30/6/15. Criterios de inclusión: edad 10 a 20 años, ambos sexos, consultaron por dolor (casos) o para control de salud y/o apto físico escolar (controles). Se utilizaron los test de chi² y de Student. Se calcularon Odds Ratios (OR). Se construyó un modelo de regresión logística binaria para evaluar independientemente cada variable asociada con dolor. Resultados. Se evaluaron 4224 historias clínicas; se incluyeron 237 casos y 468 controles. Los adolescentes con dolor tuvieron: mayor edad (p < 0,0001; OR 2,3; IC 95%: 1,6-3,2); mayor cantidad de mujeres (p < 0,0001; OR 2,24; IC 95%: 1,61-3,12); 3) mayor desarrollo puberal (p= 0,0035; OR 2,16; IC 95%: 1,3-3,6); mayor abandono escolar (p < 0,0001; OR 13,4; IC 95%: 3,9-42,9); y mayor actividad laboral (p= 0,0001; OR 3,04; IC 95%: 1,7-5,3). Solamente la edad, sexo femenino y abandono escolar se asociaron independientemente a la consulta por dolor. No hubo diferencias significativas con obesidad y constitución familiar. Conclusión. Edad mayor, sexo femenino y abandono escolar fueron factores de riesgo independientes en la consulta por dolor en adolescentes. La pubertad y el trabajo se asociaron, pero no fueron factores de riesgo independientes.

Introduction. The most common painful syndromes (headache, abdominal pain and musculoskeletal pain) develop or worsen during adolescence and are a common reason for consultation. Objective. Evaluate the association of age, sex, obesity, pubertal development, schooling level, employment and family structure with consultation for pain in adolescents. Population and methods. Case-control study conducted between February 1st, 2014 and June 30th, 2015. Inclusion criteria: ages 10 to 20 years, both sexes, consultation for pain (cases), or a checkup and/or school physical (controls). χ² test and Student" s tests were used. Odds ratios (OR) were calculated. A binary logistic regression model was constructed to independently assess each pain-related variable. Results. A total of 4224 medical records were evaluated; 237 cases and 468 controls were included. Adolescents with pain exhibited: greater age (p < 0.0001; OR 2.3; 95% CI: 1.63.2); greater number of females (p < 0.0001; OR 2.24; 95% CI: 1.61-3.12); greater pubertal development (p < 0.0035; OR 2.16; 95% CI: 1.33.6); greater school dropout level (p < 0.0001; OR 13.4; 95% CI: 3.9-42.9); greater employment levels (p < 0.0001; OR 3.04; 95% CI: 1.7-5.3). Only age, female sex and school dropout were independently associated with consultation for pain. There were no significant differences with obesity and family structure. Conclusion. Older age, female sex and school dropout were independent risk factors in consultation for pain in adolescents. Puberty and employment were associated, but were not found to be independent risk factors.

Prevalence of musculoskeletal symptoms in obese patients candidates for bariatric surgery and its impact on health related quality of life

ABSTRACT Objective This study was designed to identify the major musculoskeletal symptoms of individuals with obesity, to assess their health-related quality of life, and to evaluate the correlation between the musculoskeletal symptoms and the individuals' health-related quality of life. Materials and methods Cross-sectional study. Instruments used "Nordic Musculoskeletal Questionnaire" and "The Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36)". Results In total, 41 subjects were evaluated, of which 90.15% were female. The mean age of the subjects was 40.78 ± 9.85 years and their mean body-mass index was 46.87 ± 8.08. All subjects reported musculoskeletal pain in at least one anatomical region and 80.49% had pain in three or more regions. The activity limitations due to pain were reported by 75.61% of them. The most affected regions by pain were the ankles and/or feet, lower back, knees and wrists/hands/fingers. The most associated regions with activity limitations due to pain were the ankles and/or feet, knees and lower back. The presence of pain showed a negative correlation with the domains physical functioning (PF), role-physical (RP) and body pain (BP). The activity limitations showed a negative correlation with the domains PF, BP, social functioning (SF) and role-emotional (RE). Conclusion Our data showed a high prevalence of musculoskeletal pain and limitation in activities due to pain in obese subjects. The musculoskeletal symptoms had negative correlations with physical and mental components of the health-related quality of life, highlighting the importance of ensuring that patients with obesity have access to interdisciplinary care, for the prevention and rehabilitation of musculoskeletal disorders.

Uso de ácido hialurónico en osteoartritis de articulación temporomandibular en paciente adolescente / Use of hyaluronic acid in osteoarthritis of temporomandibular joint in adolescent patient

La osteoartritis es un tipo de trastorno temporomadibular de origen articular, siendo uno de los procesos degenerativos óseos que más comúnmente afectan a la articulación temporomandibular. Se caracteriza por remodelación del hueso subcondral subyacente, deterioro y abrasión del tejido articular. Las infiltraciones intraarticulares de ácido hialurónico se consideran beneficiosas para el tratamiento del dolor y la recuperación de propiedades de los tejidos articulares. El objetivo de éste artículo es describir el uso de ácido hialurónico en el manejo de osteoartritis de articulación temporomandibular en un paciente adolescente. Paciente de sexo femenino, 15 años de edad, presenta dolor de un año de evolución en la región preauricularbilateral, con aumento de dolor en apertura máxima. Considerando el examen clínico e imagenológico se diagnostica una luxación discal con reducción con componente osteoartritico e inflamatorio bilateral. Se indica reposo mandibular, dieta líquida, AINEs y se realiza la aplicación intraarticular de ácido hialurónico(Suprahyalâ 25 mg/2,5 ml) bilateral. Se cita a control a las 2, 3 y 16 semanas donde la paciente se encuentra sin dolor espontaneo y a la palpación. El uso de ácido hialurónico es una de las alternativas terapeúticas más utilizadas para el manejo de la osteoartritis de articulación temporomandibular, sin embargo es necesario que la evidencia de su aplicación intraarticular en adolescentes y niños se consolide.

Osteoarthritis is a type of articular origin Temporomandibular disorders, being one of themost common degenerative processes affecting thetemporomandibular joint. It is characterized byremodeling of the underlying subchondral bone,deterioration and abrasion of articular tissue. Intra-articular injections of hyaluronic acid are considered beneficial for treatment of pain and recovery of joint tissues properties. The aim of this article is to describe the use of hyaluronic acid in the management of osteoarthritis of temporomandibular joint in an adolescent patient. Female patient, 15 years old,presented pain with a year of progress in the bilateral preauricular region, with increased pain at maximum aperture. Considering the clinical and imaging tests the patient was diagnosed with disk displacement with reduction with bilateral osteoarthritic and inflammatory component. Mandibular rest, liquid diet, NSAIDs were indicated and the application of intra-articular hyaluronicacid (Suprahyalâ 25 mg / 2.5 ml) bilaterally. Control was quoted at 2, 3 and 16 weeks where the patient has no spontaneous pain and tenderness. The use of hyaluronic acid is one of the most commonly usedtherapeutic alternatives for the management ofosteoarthritis of temporomandibular joint. However,further evidence of its use in intra-articular application in adolescents and children should be incorporated.

Prevalence of musculoskeletal pain in adolescents and association with computer and videogame use / Prevalência de dor musculoesquelética em adolescentes e associação com uso de computador e jogos eletrônicos

Abstract Objective: This study investigated the presence of musculoskeletal symptoms in high school adolescents from public schools and its association with electronic device use. Methods: The sample consisted of 961 boys and girls aged 14–19 years who answered a questionnaire regarding the use of computers and electronic games, and questions about pain symptoms and physical activity. Furthermore, anthropometric assessments of all volunteers were performed. The chi-squared test and a multiple logistic regression model were used for the inferential analysis. Results: The presence of musculoskeletal pain symptoms was reported by 65.1% of the adolescents, being more prevalent in the thoracolumbar spine (46.9%), followed by pain in the upper limbs, representing 20% of complaints. The mean time of use for computers and electronic games was 1.720 and 583 minutes per week, respectively. The excessive use of electronic devices was demonstrated to be a risk factor for cervical and lumbar pain. Female gender was associated with the presence of pain in different body parts. Presence of a paid job was associated with cervical pain. Conclusion: A high prevalence of musculoskeletal pain in adolescents, as well as an increased amount of time using digital devices was observed. However, it was only possible to observe an association between the increased use of these devices and the presence of cervical and low back pain.

Resumo Objetivo: Investigar a presença de sintomas musculoesqueléticos em adolescentes estudantes do ensino médio em escolas públicas e sua associação com o uso de dispositivos eletrônicos. Método: A amostra foi composta por 961 meninos e meninas entre 14 e 19 anos que responderam questionário sobre o uso de computadores, jogos eletrônicos e questões relacionadas a sintomas dolorosos e atividade física. Além disso, todos os voluntários foram submetidos à avaliação antropométrica. Para análise inferencial foram usados os testes de qui-quadrado e modelo múltiplo de regressão logística. Resultados: A presença de sintomas de dor musculoesquelética foi reportada por 65,1% dos adolescentes, mais prevalente na coluna toracolombar (46,9%), seguida por dor nos membros superiores (20%). O tempo médio de uso de computador e jogos eletrônicos foi de 1.720 e 583 minutos por semana, respectivamente. O uso excessivo dos dispositivos eletrônicos mostrou-se como fator de risco para dor cervical e lombar. O sexo feminino apresentou associação com a presença de dor em diferentes partes do corpo. A atividade profissional esteve associada com a dor cervical. Conclusão: Observou-se alta prevalência de dor musculoesquelética nos adolescentes e elevado tempo de uso dos dispositivos eletrônicos. Entretanto, foi possível observar somente a associação do uso excessivo desses dispositivos e a presença de dor cervical e lombar.

Revisión bibliográfica: factores de riesgo en patologías musculoesqueléticas / Bibliographic review: risk factors on musculoskeletal diseases

Introducción: las enfermedades musculoesqueléticas tienen elevada prevalencia y alto impacto socio económico sobre el bienestar de la población y la productividad económica de un país. En Chile, este grupo de patologías constituyen la principal causade enfermedades profesionales y con mayores tasas anuales de licencias médicas laborales, aún cuando se considera que estas enfermedades, en la actualidad, estarían siendo subnotificadas. Independiente del origen de la enfermedad, el dolor y la impotencia funcional son los principales síntomas en este grupo de patologías, al conducir el diagnóstico y tratamiento y guiar la indicación de reposo y reintegro laboral. En su fisiopatología interactúanfrecuentemente una serie de riesgos personales y ambientales, entre los que se encuentran factores de riesgo laborales, siendo reconocidas algunas de estas patologías entre el listado deenfermedades profesionales de la Organización Internacional del Trabajo. Sin intención de saldar el debate sobre el origen de este grupo de patologías, sino con el fin de aportar evidencia ala discusión sobre la compleja interacción entre sus factores de riesgo, presentamos una revisión bibliográfica sobre enfermedades osteomusculares observadas con frecuencia en la población. Metodología: Se seleccionaron 11 patologías musculoesqueléticas de diagnóstico frecuente en población económicamente activa y que generan ausentismo laboral: Cervicalgia, Dorsalgia, Epicondilitis, Lumbago Mecánico, Quiste Sinovial, Tendinitis Aquiliana, TendinitisBicipital, Tendinitis del Manguito Rotador, Tendinitis Rotuliana, Tenosinovitis de De Quervain, Síndrome del Túnel Carpiano. Se realizó una revisión de la literatura registrada en las principales bases de datos a nivel internacional y una búsqueda manual de estudios referenciados en los artículos principales...

Introduction: musculoskeletal diseases have highprevalence and socioeconomic impact on population’swellbeing and countries’ economic productivity. In Chile,this group of pathologies constitute the main cause ofprofessional diseases, with the highest working leaveperiods annual rate, even though it is considered that thisdiseases are being subnotified. Independent of diseaseorigin, pain and functional impotence are main symptomson this group of pathologies, conducting its diagnosis andtreatment, and guiding the indication of rest and return towork. In its pathophysiology several personal and ambientrisks interact, with occupational risk factors in-between,being some of the diseases recognized on the InternationalWork Organization’s list of Professional Diseases. Withoutintention of settle the debate about the origin of thisgroup of diseases, but with intention of contribute withevidence to the discussion of the complex interactionbetween its risk factors, we present a bibliographic reviewof musculoskeletal diseases observed with frequency.Methodology: 11 musculoskeletal diseases of frequentdiagnosis on economically active population that produceworking absenteeism were selected: Cervicalgia, Dorsalgia,Epicondylitis, Low back pain, Synovial Cyst, AchillesTendinitis, Bicipital Tendinitis, Rotator Cuff Tendinitis,Patellar Tendinitis, De Quervain Tenosynovitis and CarpalTunnel Syndrome. A literature review registered on maininternational databases was performed, and a manualsearch of studies cited on main articles...

Ergonomía: una ciencia que aporta al bienestar odontológico / Ergonomics: a science contributing to dental welfare

El conocimiento y la aplicación de los principios ergonómicos en la práctica odontológica traen consigo beneficios para el profesional, sus ayudantes y los pacientes, logrando un trabajo organizados, eficiente y a un costo compatible con los intereses de todas las partes. Uno de los aspectos en los que la ergonomía ha aportado más a la odontología es en lo referente a la economía de movimientos y tiempos. El objetivo del presente trabajo es facilitar al personal odontológico el conocimiento de los factores de riesgo a los que está expuesto, sus efectos y las medidas de protección y/o prevención. La ergonomía aplicada a la odontología reduce las tensiones durante los procedimientos, tanto del profesional como del personal auxiliar, siendo el paciente el beneficiado al final del servicio que le hemos ofrecido.

Fatores associados à dor musculoesquelética em escolares da rede pública municipal no extremo sul do Brasil / Factors associated with musculo-skeletal pain in municipal public school students in the far South of Brazil

Identificar os fatores associados à dor musculoesquelética (DME) em escolares da rede municipal de ensino na cidade de Rio Grande, extremo sul do Brasil, entre junho e dezembro de 2010. Métodos: trata-se de um estudo seccional conduzido em uma amostra aleatória de 625 escolares entre seis e 18 anos de idade. A DME foi pesquisada utilizando o Questionário Nórdico de Sintomas Osteomusculares (QNSO) e informações demográficas, biológicas, forma de transporte do material escolar e de estilo de vida obtidas via questionário padronizado. As razões de prevalência bruta e ajustada da associação da DME com os fatores investigados foi estimada em um modelo de regressão de Poisson. Resultados: a prevalência de DME foi de 37,6 por cento. Idade entre 11 e 18 anos (RP=1,70; IC95 por cento=1,36- 2,11; p<0,001), sexo feminino (RP=1,47; IC95 por cento=1,19-1,81; p<0,001) e histórico familiar de distúrbio na coluna (RP=0,78; IC95 por cento=0,64-0,96; p=0,020) estiveram associados ao desfecho. Não praticar esportes de competição foi um fator de proteção (RP=0,65; IC95 por cento=0,51-0,81; p<0,001). Conclusão: estes resultados confirmam a influência negativa de diferentes fatores presentes no ambiente escolar sobre a saúde dos estudantes. Considera-se como medida importante a implantação de programas de promoção da saúde nas escolas, que estimulem entre os estudantes a adoção de práticas saudáveis que minimizem os efeitos deletérios da DME...

To identify the factors associated with musculo-skeletal pain (MSP) in schoolchildren in municipal public schools in the city of Rio Grande, in the far south of Brazil, between June and December 2010. Methods: a sectional study was carried out with a random sample of 625 schoolchildren aged between six and eighteen years of age. MSP was investigated using the Nordic Osteomuscular Symptoms Questionnaire (NOSQ) and information relating to demographic and biological factors, the means of transport of school materials and lifestyle, obtained using a standardized questionnaire. The raw and adjusted prevalence rations for association between MSP and the factors under study were estimated using a Poisson regression model. Results: the prevalence of MSP was 37.6 percent. Being aged between 11 and 18 years (PR=1.70; CI95 percent=1.36-2.11; p<0.001), being female (PR=1.47; CI95 percent=1.19-1.81; p<0.001) and a family history of back pain (PR=0.78; CI95 percent=0.64-0.96; p=0.020) were associated with the outcome. Not practicing competitive sports was a protective factor (PR=0.65; CI95 percent=0.51-0.81; p<0.001). Conclusions: these results confirm the negative influence of various factors present in the school environment on the health of students. It is considered an important measure to introduce health promotion programs in schools to encourage students to adopt healthy practices that minimize the deleterious effects of MSP...

Dolor musculoesquelético en tripulantes de tanques petroleros venezolanos / Musculoskeletal pain in Venezuelan oil tanker crews

El objetivo de esta investigación fue analizar la prevalencia de dolor musculoesquelético (DoME) en 155 tripulantes de tanqueros petroleros venezolanos. Se realizó un estudio descriptivo y transversal, aplicando el cuestionario Estandarizado Nórdico. La prevalencia de DoME (n=127) fue de 82%. La edad en los tripulantes que refirieron DoME fue 39,29 ± 10,16 años, rango 24-60 años y los que lo negaron fue de 34,93 ± 9,76 años, rango 24-58 años (p<0,05); el IMC del grupo con DoME fue de 29,94 ± 4,31 Kg/m², mientras que el otro fue de 30,02 ± 4,96 Kg/m². El 83% de los tripulantes con DoME tenían una antigüedad laboral de 10 años o menos (4,31 ± 2,44 años). La ocurrencia de DoME para los tripulantes de sala de máquinas y de cubierta fue similar (50%) y su frecuencia por región anatómica fue: 57% en espalda inferior, 32% en rodillas, 24% en cuello, 24% en espalda superior y 19% hombros. Se demostró asociación directa significativa (p<0,05) entre el DoME de espalda baja y antigüedad, así como entre edad e IMC (p<0,01); cargo con el área de trabajo; y una asociación inversa significativa (p<0,01) entre lumbalgia y DoME de rodillas, edad y dolor de cuello y antigüedad laboral en el tanquero con el cargo. Los tripulantes en área de cubierta mostraron una ocurrencia más alta de DoME en cuello (33%) que los de máquinas (15%) (p<0,01). Estos hallazgos sugieren la necesidad de implementar programas de salud para reducir la ocurrencia de DoME en el lugar de trabajo.

The objective of this investigation was to analyze the prevalence of musculoskeletal pain (MSP) in oil tanker crew members in Venezuela. A descriptive cross-sectional study was implemented, using a modified version of the Standardized Nordic Questionnaires. The prevalence of MSP in 127 men was 82%. The mean age was statistically different (p < 0.05) between the MSP group (39.29 ± 10.16 years, range 24-60) and the no-MSP group (34.9 ± 9.76 years, range 24-58 years). There was no significant difference between the body mass indexes (BMI) of the MSP group (29.94 ± 4.31 kg/m²) and the no-MSP group (30.02 ± 4.96 km/m²). The majority of the crew members with MSP (83%) had ≤ 10 years seniority, mean value of 4.31 ± 2.44 years. MSP occurrence was the same (50%) for crew members located in engine rooms and decks. The MSP frequency for anatomical region was 57% in lower back, 32% knees, 24% in neck and upper back and 19% shoulders. There was a significant association between lower back pain and seniority (p < 0.05), also between age and BMI (p < 0.01); and an inverse significant correlation (p < 0.01) between lower back pain and knee pain, age and neck pain and seniority in the job. The crew members in the deck area showed a higher occurrence of neck pain (33%) than the engine crew (16%) (p< 0.01). Our findings suggest the need to implement health programs to reduce the occurrence of MSP in the workplace.

Musculoskeletal pain, profile and quality of life of individuals with sickle cell disease / Dor osteomuscular, perfil e qualidade de vida de indivíduos com doença falciforme

BACKGROUND: Sickle cell disease is a prevalent condition in Brazil. Its clinical presentation includes vascular occlusion that result in ischemia, inflammation, dysfunctions, pain and chronic hemolysis, causing irreversible damage and compromising quality of life. OBJECTIVE: The objectives of this study were to verify the relationship between musculoskeletal pain, from different body parts, with social economic characteristics and quality of life among individuals with sickle cell disease. METHODS: 27 individuals with sickle cell disease were interviewed with the use of a structured questionnaire with questions about personal, social, economic and cultural variables, the Nordic musculoskeletal symptoms questionnaire and the SF-36 Health Survey. Data were analyzed descriptively using frequencies and percentages. The inferential Chi-Square test was used for dichotomous variables and the Student t- test for continuous variables, with a significance of 5%. A logistic regression was performed using all variables that correlated with pain as dependent variables. RESULTS: The mean age was 31.77 years, predominantly male, black, registered active employment, with average education and income up to three minimum wages. The regions most affected by pain were hip/limbs, chest, lower back and arms. Physical Functioning from the SF-36 had the highest score and mental health the lowest score. Musculoskeletal pain was present in the arms, chest and lower back. Social Functioning was not associated with pain, indicating the influence of other factors. Arm pain was more frequent in black individuals and those with low education. CONCLUSION: Body pain was associated with race and education and all pain areas were associated with the physical components of the SF-36. Pain was significantly associated with vitality and mental health components of the SF-36.

CONTEXTUALIZAÇÃO: As doenças falciformes constituem um grupo frequente no Brasil. Suas alterações ocasionam vaso-oclusão, resultando em isquemia, inflamação, disfunções, dor e hemólise crônica, gerando danos irreversíveis, comprometendo a qualidade de vida. OBJETIVO: Verificar a relação entre a dor osteomuscular, considerando sua localização corporal, e características sociais, econômicas e de qualidade de vida em indivíduos com doença falciforme. MÉTODOS: Foram coletadas informações pessoais, sociais e econômicas, além de dados do Questionário Nórdico de Sintomas Osteomusculares (QNSO) e Short Form 36 em 27 indivíduos. Os dados foram analisados descritivamente por meio de frequências e porcentagens. A análise inferencial usou o teste do qui-quadrado (variáveis dicotômicas) e t de Student (variáveis contínuas), com significância de 5%. Análises de regressão logística utilizaram como variáveis dependentes cada uma das que se relacionaram com dor. RESULTADOS: A média de idade foi de 31,77 anos, predominando sexo masculino, negros, emprego ativo, escolaridade média e rendimento inferior a três salários mínimos. Quadril/membros inferiores, região dorsal, lombar e braços foram mais acometidos pela dor. A capacidade funcional apresentou o maior valor, e saúde mental, o menor. Aspectos físicos foram comprometidos pela dor nos braços, coluna dorsal e lombar. Aspectos sociais não se associaram com a dor, indicando influência de outros fatores. A dor nos braços foi mais frequente entre os negros e os com baixa escolaridade. CONCLUSÃO: A dor nas regiões corporais analisadas relacionou-se com a raça e a escolaridade e com todos os domínios referentes ao componente físico do SF-36. Os componentes vitalidade e saúde mental apresentaram associação significativa com a dor.

Homozygous sickle cell disease in Uganda and Jamaica a comparison of Bantu and Benin haplotypes / La anemia de células falciformes homocigóticas en Uganda y Jamaica comparación de haplotipos Bantú y Benin

OBJECTIVE: To compare the haematological and clinical features of homozygous sickle cell (SS) disease in Bantu and Benin haplotypes in a cross-sectional study of 115 Ugandan patients attending the Sickle Cell Clinic at Mulago Hospital, Kampala, Uganda, with 311 patients in the Jamaican Cohort Study. METHODS: This involved comparison of clinical features and haematology with special reference to genetic determinants of severity including fetal haemoglobin levels, beta-globin haplotype and alpha thalassaemia status. RESULTS: The Bantu haplotype accounted for 94% of HbS chromosomes in Ugandan patients and the Benin haplotype for 76% of HbS chromosomes in Jamaica. Ugandan patients were marginally more likely to have alpha thalassaemia, had similar total haemoglobin and fetal haemoglobin levels but had higher reticulocyte counts and total bilirubin levels consistent with greater haemolysis. Ugandan patients had less leg ulceration and priapism, but the mode of clinical presentation, prevalence of dactylitis, features of bone pain and degree of delay in sexual development, assessed by menarche, were similar in the groups. In Ugandan patients, a history of anaemic episodes was common but these were poorly documented. CONCLUSION: The haematological and clinical features of the Bantu haplotype in Uganda were broadly similar to the Benin haplotype in Jamaica except for less leg ulceration and priapism and possibly greater haemolysis among Ugandan subjects. Anaemic episodes in Uganda were treated empirically by transfusion often without a clear diagnosis; better documentation including reticulocyte counts and observations on spleen size is necessary to evolve appropriate models of care.

OBJETIVO: Comparar los rasgos clínicos de la anemia de células falciformes homocigóticas (SS) en los haplotipos Bantú y Benin en un estudio transversal de 115 pacientes ugandeses que asisten a la Clínica de la anemia de células falciformes en el Hospital de Mulago, Kampala, Uganda, con 311 pacientes en un estudio de cohorte jamaicano. MÉTODOS: El estudio conllevó la comparación de los rasgos clínicos y hematológicos con referencia especial a los determinantes genéticos de la severidad, incluyendo los niveles de la hemoglobina fetal, haplotipos del gen de la globina beta, y el estado de la alfa talasemia. RESULTADOS: El haplotipo Bantú dio cuenta del 94% de los cromosomas HbS en los pacientes ugandeses, en tanto que los haplotipos Benin dieron cuenta del 76% de los cromosomas de HbS en Jamaica. Los pacientes de Uganda presentaron una probabilidad marginalmente mayor de alfa talasemia, tenían niveles similares de hemoglobina total y hemoglobina fetal, pero en cambio presentaban conteos más altos de reticulocitos así como niveles mayores de bilirrubina total, en correspondencia con una mayor hemólisis. Los pacientes ugandeses presentaban menor ulceración de las piernas y priapismo, pero el modo de presentación clínica, la prevalencia de dactilitis, los rasgos de dolor óseo, y el grado de retraso en el desarrollo sexual, evaluado por la menarquia, fueron similares en todos los grupos. Los pacientes de Uganda se caracterizaron comúnmente por una historia de episodios de anemia, pobremente documentados. CONCLUSIÓN: Los rasgos clínicos y hematológicos del haplotipo Bantú en Uganda fueron considerablemente similares al haplotipo Benin en Jamaica, salvo por una menor presencia de ulceración de las piernas y priapismo, así como posiblemente mayor hemólisis entre los sujetos de Uganda. Los episodios de anemia en Uganda fueron tratados empíricamente mediante transfusión, a menudo sin un diagnóstico claro. Se necesita una mejor documentación - incluyendo conteos de reticulocitos - así como observaciones del tamaño del bazo, a fin de desarrollar modelos de cuidado apropiados.

Dor musculoesquelética em membros inferiores de pacientes obesos antes e depois da cirurgia bariàtrica / Musculoskeletal pain in lower limbs in obese patients before and after bariatric surgery

RACIONAL: A Organização Mundial da Saúde calcula que em 2015 haverá aproximadamente 2,3 bilhões de adultos com sobrepeso e mais de 700 milhões com obesidade no mundo. O excesso de peso pode levar a inúmeras complicações, dentre elas as doenças articulares degenerativas. OBJETIVO: Estimar a frequência e local da dor músculoesquelética em membros inferiores antes e depois da cirurgia bariátrica. MÉTODO: Estudo descritivo de corte transversal, composto por 22 indivíduos obesos que preencheram questionários antes e seis meses depois de submetidos à cirurgia bariátrica. Os dados foram expressos através de uma análise descritiva e avaliados estatiscamente com nível de significância de 5%. RESULTADOS: A dor foi referida pelos pacientes no pré-operatório em 87,5% no tornozelo e pé, 80% em joelho e 91,7% no quadril. No pós-operatório ela diminuiu para 12,5% no tornozelo e pé, 20% no joelho e 8,3% no quadril atingindo significância estatística (p<0,001). CONCLUSÃO: Indivíduos obesos submetidos à cirurgia bariátrica apresentaram acentuada redução tanto na frequência quanto na intensidade das dores músculoesqueléticas localizadas em ordem no quadril, tornozelo e pé e joelho.

BACKGROUND: The World Health Organization estimates that in 2015 there will be approximately 2.3 billion overweight adults and more than 700 million obese individuals worldwide. Excess weight can lead to several complications, such degenerative diseases. AIM: To estimate the frequency and local of musculoskeletal pain in the lower limbs before and after bariatric surgery. METHODS: Cross-sectional descriptive study consisting of 22 obese individuals who filled in questionnaires before and six months after undergoing bariatric surgery. Data were shown through a descriptive analysis. The statistical analysis was performed with significance level at 5%. RESULTS: Musculoskeletal pain in the lower limbs was placed preoperatively in 87.5% in the ankle and foot, knee 80% and 91.7% in the hip. Postoperative pain remained present in 12.5% in the ankle and foot, knee 20% and 8.3% in the hip, with statistical significance (p <0.001). CONCLUSION: Obese people who underwent bariatric surgery experienced a marked reduction in both frequency and intensity of musculoskeletal pain located in order in the hip, ankle and foot, and knee.

Dor músculo-esquelética em adolescentes obesos / Musculoskeletal pain in obese adolescents

OBJETIVO: Avaliar presença de dor, síndromes músculo-esqueléticas, alterações ortopédicas e uso de computador e videogame em adolescentes obesos. MÉTODOS: Um estudo transversal avaliou 100 adolescentes consecutivos com obesidade e 100 eutróficos a partir de um questionário confidencial, autoaplicável, incluindo dados demográficos, prática esportiva, sintomas dolorosos do sistema músculo-esquelético e uso de computador e videogame. Pré-teste e reteste do questionário foram realizados. O exame físico avaliou seis síndromes músculo-esqueléticas e sete alterações ortopédicas. RESULTADOS: O índice de kappa entre pré-teste e reteste foi 0,724. Dor e síndromes músculo-esqueléticas foram igualmente prevalentes nos dois grupos (44 versus 56 por cento, p = 0,09; 12 versus 16 por cento, p = 0,541; respectivamente). Entretanto, alterações ortopédicas (98 versus 76 por cento, p = 0,0001), encurtamento de quadríceps (89 versus 44 por cento, p = 0,0001) e geno valgo (87 versus 24 por cento, p = 0,0001) foram significantemente mais evidenciados nos obesos versus controles. As medianas do tempo de uso do computador no dia anterior à pesquisa, nos sábados e domingos foram menores nos obesos (30 versus 60 minutos, p = 0,0001; 1 versus 60 minutos, p = 0,001; 0 versus 30 minutos, p = 0,02; respectivamente). Uso de minigame foi menor nos obesos (2 versus 11 por cento, p = 0,003), não havendo diferença no uso de videogame nos dois grupos (p > 0,05). Comparações entre obesos com e sem dor evidenciaram maior frequência no gênero feminino (59 versus 39 por cento, p = 0,048) e maior mediana de tempo de uso nos domingos [0 (0-720) versus 0 (0-240) minutos, p = 0,028]. CONCLUSÕES: Obesidade pode causar danos ao sistema osteoarticular no início da adolescência, principalmente nos membros inferiores. Programas específicos para adolescentes obesos do sexo feminino com dor músculo-esquelética precisam ser desenvolvidos.

OBJECTIVE: To determine the prevalence of pain, musculoskeletal syndromes, orthopedic disorders and using computers and playing videogames among obese adolescents. METHODS: This was a cross-sectional study that investigated 100 consecutive obese adolescents and 100 healthy-weight controls using a confidential, self-report questionnaire covering demographic data, sports participation, painful musculoskeletal system symptoms and using computers and playing videogames. The questionnaire’s test-retest reliability was tested. Physical examination covered six musculoskeletal syndromes and seven orthopedic disorders. RESULTS: The kappa index for test-retest was 0.724. Pain and musculoskeletal syndromes were equally prevalent in both groups (44 vs. 56 percent, p = 0.09; 12 vs. 16 percent, p = 0.541; respectively). Notwithstanding, orthopedic disorders (98 vs. 76 percent, p = 0.0001), tight quadriceps (89 vs. 44 percent, p = 0.0001) and genu valgum (87 vs. 24 percent, p = 0.0001) were significantly more prevalent in obese adolescents than in controls. Median time spent using a computer the day before, on Saturdays and on Sundays were all lower among the obese subjects (30 vs. 60 minutes, p = 0.0001; 1 vs. 60 minutes, p = 0.001; and 0 vs. 30 minutes, p = 0.02; respectively). Obese adolescents were less likely to play handheld videogames (2 vs. 11 percent, p = 0.003) and there was no difference in the two groups’ use of full-sized videogames (p > 0.05). Comparing obese adolescents with pain to those free from pain revealed that pain was more frequent among females (59 vs. 39 percent, p = 0.048) and was associated with greater median time spent playing on Sundays [0 (0-720) vs. 0 (0-240) minutes, p = 0.028]. CONCLUSIONS: Obesity can cause osteoarticular system damage at the start of adolescence, particularly to the lower limbs. Programs developed specifically for obese female adolescents with musculoskeletal pain are needed.

Discrimination of acute lymphoblastic leukemia from systemic-onset juvenile idiopathic arthritis at disease onset

OBJECTIVE: To assess clinical and laboratory features that differentiate acute lymphoblastic leukemia from systemic juvenile idiopathic arthritis at disease onset. METHODS: Fifty-seven leukemia patients with musculoskeletal involvement, without blasts on peripheral blood and without glucocorticoid therapy at disease onset and 102 systemic juvenile idiopathic arthritis patients (International League of Associations for Rheumatology criteria) were retrospectively evaluated. The following features were examined: fever, rheumatoid rash, arthritis, limb pain, hepatomegaly, splenomegaly, pericarditis, myocarditis, pleuritis, weight loss, bleeding, anemia, leukopenia, neutropenia, thrombocytopenia, erythrocyte sedimentation rate, and lactic dehydrogenase levels. RESULTS: The median age at disease onset was significantly higher in leukemia patients than in those with systemic-onset juvenile idiopathic arthritis (5.8 vs. 3.8 years). In addition, the frequencies of limb pain, hepatomegaly, weight loss and hemorrhagic manifestations were significantly higher in leukemia patients than in systemic-onset juvenile idiopathic arthritis patients (70 percent vs. 1 percent, 54 percent vs. 32 percent, 30 percent vs. 8 percent, and 9 percent vs. 0 percent, respectively). Likewise, the frequencies of anemia, leukopenia, neutropenia, thrombocytopenia and high lactic dehydrogenase levels were statistically higher in leukemia patients than in patients with systemic-onset juvenile idiopathic arthritis (88 percent vs. 57 percent, 39 percent vs. 1 percent, 60 percent vs. 1 percent, 77 percent vs. 1 percent, and 56 percent vs. 14 percent, respectively). Remarkably, multivariate analysis revealed that limb pain (OR = 553; 95 percent CI =46.48-6580.42) and thrombocytopenia (OR = 754.13; 95 percent CI =64.57-8806.72) were significant independent variables that differentiated leukemia from systemic-onset juvenile idiopathic arthritis. The R2 of the Nagelkerke test was 0.91, and the Kaplan-Meier survival curves were similar for acute lymphoblastic leukemia patients with and without limb pain. CONCLUSION: Our study emphasizes the importance of investigating leukemia in patients presenting with musculoskeletal manifestations and, in particular, limb pain associated with thrombocytopenia.