RESUMEN
Elephantiasis nostras verrucosa, a rare manifestation of Kaposi's sarcoma, is a progressive cutaneous hypertrophy caused by chronic non-filarial lymphedema secondary to obstruction of the lymphatic system that can lead to severe disfigurement of parts of the body that have gravity-dependent blood flow, due to edema, fibrosis, and hyperkeratosis, especially lower extremities. Among the various conditions that can induce chronic lymphedema are tumors, trauma, radiotherapy, obesity, hypothyroidism, chronic venous stasis, and AIDS-related Kaposi's sarcoma. Kaposi's sarcoma is a vascular tumor associated with the presence of human gammaherpesvirus 8 that is predominantly cutaneous, locally aggressive, with metastasis, and is associated with the production of factors that favor inflammation, lymphatic obstruction, and lymphedema.
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Sarcoma de Kaposi/complicaciones , Infecciones Oportunistas Relacionadas con el SIDA/complicaciones , Elefantiasis/diagnóstico , Sarcoma de Kaposi/patología , Sarcoma de Kaposi/tratamiento farmacológico , Didanosina/uso terapéutico , Infecciones Oportunistas Relacionadas con el SIDA/patología , Infecciones Oportunistas Relacionadas con el SIDA/tratamiento farmacológico , Lamivudine/uso terapéutico , Fármacos Anti-VIH/uso terapéutico , Ciclopropanos , Benzoxazinas/uso terapéutico , Quimioterapia Combinada , Elefantiasis/etiología , Elefantiasis/patología , AlquinosRESUMEN
Demonstra-se quadro raro de Elefantíase Nostra, na sua forma verrucosa, no dorso de pé de homem de 80 anos por episódios prévios de erisipela de repetição. As lesões confluentes vegetantes e difusas em dorso de pé são comparáveis aos corais Trumpet Coral (Caulastrea curvata).
Study of a rare case of Elephantiasis Nostra in verrucous form on the dorsum of the foot of an 80year-old male with a history of recurrent erysipelas infection. The vegetant, confluent lesions on the foot resemble Trumpet Coral (Caulastrea curvata).
Asunto(s)
Anciano de 80 o más Años , Humanos , Masculino , Elefantiasis/etiología , Erisipela/complicaciones , Dermatosis del Pie/etiología , Enfermedad Crónica , Elefantiasis/patología , Dermatosis del Pie/patologíaRESUMEN
Grave's disease is an autoimmune disease of thyroid gland and pretibial myxedema occurs in 4% of these patients. We present a 50-year-old man with Grave's disease who was referred with nonpitting, edematous, erythematous plaques on legs and feet that became elephantiasic. Biopsy of skin revealed granular material deposition in dermis with splitting of collagen fibers. This is a rare presentation of pretibial myxedema that presented in this case