Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 3 de 3
Filtrar
1.
Rev. bras. oftalmol ; 79(1): 69-70, Jan.-Feb. 2020. graf
Artículo en Inglés | LILACS | ID: biblio-1092664

RESUMEN

Abstract Hemoglobin C is the second most frequent Hb variant in Brazil and the world. Hemoglobin C trait is described as a benign and asymptomatic condition. There is little information in the literature about the association of retinal vascular disease and the presence of hemoglobin AC, being this information restricted to a few case reports. This case report describes a 26-year-old female patient with hemoglobin C trait. She presents areas of non-perfusion and arteriovenous shunts in the retinal temporal periphery of the left eye, like changes in Goldberg's stage II of proliferative sickle retinopathy. After three years of follow-up, the patient exhibits the same the alteration in right eye as well.


Resumo A hemoglobina C é a segunda variante de hemoglobina mais comum no Brasil e no mundo. O traço C é descrito como uma condição benigna e assintomática. Há pouca informação na literatura sobre a associação de doença vascular retiniana e a presença de hemoglobina AC, sendo esta informação restrita a alguns poucos relatos de casos. Este relato de caso descreve uma paciente do gênero feminino de 26 anos de idade com traço C. Ela apresenta áreas de não perfusão e shunts artério-venosos na periferia temporal da retina do olho esquerdo, similar ao estágio II de Goldberg de retinopatia proliferativa falciforme. Após três anos de acompanhamento, a paciente apresentou a mesma alteração também em olho direito.


Asunto(s)
Humanos , Femenino , Adulto , Enfermedades de la Retina/etiología , Enfermedad de la Hemoglobina C/complicaciones , Enfermedades de la Retina/sangre , Enfermedad de la Hemoglobina C/sangre , Anemia de Células Falciformes/complicaciones , Anemia de Células Falciformes/sangre
2.
Southeast Asian J Trop Med Public Health ; 2002 Dec; 33(4): 855-61
Artículo en Inglés | IMSEAR | ID: sea-35537

RESUMEN

A brief survey of abnormal hemoglobin variants among the major ethnic groups of Karachi was conducted; 202,600 subjects were studied. Patients with low hemoglobin (Hb), low mean cell volume (MCV) and mean cell hemoglobin (MCH) including anemia, microcytosis, hypochromic hemolysis and target cells, were refered for the identification of hemoglobinopathy by molecular methods. Population screening showed that 60% had iron-deficiency anemia and 40% had hemolytic anemia, of which 20.6% was due to beta-thalassemia major, 13% beta-thalassemia trait, 5.1% sickle cell disease, 0.76% hemoglobin D Punjab (HbD Punjab), 0.32% hemoglobin C (HbC), and 0.22% hereditary persistence of fetal hemoglobin (HPFH).


Asunto(s)
Anemia Ferropénica/sangre , Anemia de Células Falciformes/sangre , Emigración e Inmigración , Enfermedades Endémicas/estadística & datos numéricos , Epidemiología Molecular , Índices de Eritrocitos , Hemoglobina Fetal , Genotipo , Enfermedad de la Hemoglobina C/sangre , Hemoglobinopatías/sangre , Hemoglobinas Anormales , Heterocigoto , Humanos , Malaria/epidemiología , Tamizaje Masivo , Mutación/genética , Pakistán/epidemiología , Fenotipo , Vigilancia de la Población , Prevalencia , Encuestas y Cuestionarios , Rasgo Drepanocítico/sangre , Salud Urbana/estadística & datos numéricos , Talasemia alfa/sangre , Talasemia beta/sangre
3.
Rev. bras. genét ; 17(4): 435-8, dez. 1994. tab
Artículo en Inglés | LILACS | ID: lil-164716

RESUMEN

The efficiency and viability of a hemoglobinopathy program was investigated. The program was offered on a voluntary basis to a Brazilian community (Araras, SP) and started with the blood analyses of pregnant women. A total of 2209 pregnant women were screened in the first 39 months and 80 heterozygotes were diagnosed (52 AS, 19 AT and 9 AC). Another 1003 persons related to these heterozygotes were examined and a total of 432 heterozygotes were diagnosed (241 AS, 140 AT and 51 AC), added to 13 patients with chronic hemolytic anemia (8 SS, 3 SC, 1 TT and 1 CC) and 16 risk couples, made up of two heterozygotes. The examination percentages of pregnant women (100 per cent), newly born children (75 per cent), other children (97 per cent), husbands (56 per cent ) and other relatives (64 per cent) showed the high rate of acceptance of the program in the community. Genetic counselling was accepted by 60 per cent of the heterozygotes over 15 years of age.


Asunto(s)
Humanos , Masculino , Femenino , Embarazo , Recién Nacido , Lactante , Preescolar , Niño , Adolescente , Adulto , Asesoramiento Genético , Planes y Programas de Salud , Hemoglobina C/análisis , Hemoglobina Falciforme/análisis , Hemoglobinopatías/sangre , Heterocigoto , Anemia de Células Falciformes/sangre , Talasemia beta/sangre , Brasil , Enfermedad Crónica , Enfermedad de la Hemoglobina C/sangre , Diagnóstico Prenatal , Muestreo Aleatorio Simple
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA