Research progress of bone marrow edema-like lesions in knee osteoarthritis / 中国骨伤

Knee osteoarthritis-associated bone marrow edema-like lesions (KOA-BMLs) is a common MRI imaging feature, which is mainly manifested as abnormal bone marrow hyperintensity in subchondral bone on T2 imaging. The formation of KOA-BMLs may be related to the abnormality of lower limb force line and subchondral bone perfusion, and related histopathological studies showed that the remodeling of bone and bone marrow in these damaged areas was abnormally increased. In KOA patients, the size of BMLs can fluctuate or even disappear in a relatively short period of time, and was closely related to pain, subchondral bone cyst formation, and the progression of KOA. However, the current treatment methods for KOA-BMLs are limited, and there is no uniform guideline or expert consensus, mainly includingmedication, physical therapy and surgical treatment. This article reviews the research progress of the disease characteristics and treatment of KOA-BMLs in order to provide guidance for the clinical diagnosis and treatment of KOA-BMLs.

Monoartritis del codo e infarto óseo como presentación inicial de enfermedad linfoproliferativa / Elbow monoarthritis and bone infarction as a form of presentation of B cell lymphoma: case report

We report a 68-year-old woman presenting with pain and swelling in her left elbow. An elbow magnetic resonance with gadolinium evidenced bone marrow infiltration and a bone infarct. Given these findings, a body CT scan was performed which showed multiple mesenteric adenopathies and a large retroperitoneal mass. A lymph node biopsy confirmed a B cell lymphoma. Monoarthritis with no systemic manifestations represents a highly uncommon form of presentation of lymphoma. Moreover it usually affects inferior limbs, particularly in the presence of bone infarction.

Role of magnetic resonance imaging in the evaluation of bone marrow disorders

To determine the role of Magnetic resonance imaging [MRI] in evaluation of bone marrow disorders. Front 2010 to May 2012, suspected bone marrow lesions were evaluated by MRI in 159 cases [94 males and 65 females]. Bone Marrow pathology included in this study were classified into two groups: malignant and non malignant: 66 patients [41.5%] malignant and 93 patients [58.5%] non-malignant, The 66 patients with malignant group included 33 [50.0%] cases of metastatic disease, 14[21.2%] cases of lymphoma, 10[15.2%] cases of myeloma and 3[4.5%] cases of leukemia. The 93 patients of non-malignant group included 18[19.4%] cases of osteoporotic collapse, 18[19.4%] cases of infectious and inflammatory marrow disorders, 21[22.6] cases of Marrow oedema, 14[15.1%] cases of primary bone tumor, 8[8.6%] cases of marrow reconversion, 10[10.8%] cases of marrow ischemia, 5[5.4%] cases of marrow degenerative disease and 4[4.3%] cases of marrow depletion, myelofibrosis and miscellaneous disorders, MRI is superior to other imaging modalities in evaluating bone marrow because it is remarkably sensitive in detecting lipid, therefore, MRI can be used to detect processes that alter the relative amounts of fat and water in bone marrow. In order to interpret the appearances of marrow seen on MRI and to distinguish normal from abnormal, it is important to understand the normal components and composition of bone marrow, which vary greatly with age and anatomic location within the skeleton. The hone marrow can be affected by infectious, inflammatory, metabolic, and neoplastic processes. Its appearance can he affected as well by underlying degenerative changes, trauma, and numerous iatrogenic therapies, including vertebroplasty, radiation or chemotherapy, and medications designed to stimulate the bone marrow