Endocarditis micótica en un recién nacido de extremadamente bajo peso al nacer: A propósito de un caso / Fungal endocarditis in an extremely low birth weight infant: Case report

Las tasas de supervivencia de los recién nacidos prematuros se han incrementado gracias a los avances tecnológicos y los conocimientos en constante evolución, aunque la sepsis de aparición tardía es más frecuente debido a los períodos prolongados de hospitalización de estos niños. Presentamos el caso de un recién nacido prematuro de extremadamente bajo peso al nacer hospitalizado con síndrome de dificultad respiratoria, enterocolitis necrosante y sepsis fúngica con endocarditis por Candida albicans. Se le administró tratamiento antimicótico hasta que se resolvió la vegetación fúngica. La sepsis y la endocarditis de origen micótico podrían ser una causa de morbilidad significativa en los recién nacidos prematuros. En este artículo revisamos las publicaciones científicas recientes acerca de los factores de riesgo, el diagnóstico, el tratamiento y la prevención de la sepsis fúngica en estos neonatos de alto riesgo.

Survival rates of premature infants have increased with developing technology and evolving knowledge but late-onset sepsis is more frequent due to prolonged hospitalization periods of these infants. We report the case of an extremely low birth weight premature infant who was admitted with respiratory distress syndrome, developed necrotizing enterocolitis and fungal sepsis with endocarditis by Candida albicans. He was treated with antifungal therapy until fungal vegetation resolved. Fungal sepsis and endocarditis may be an important morbidity in preterm infants; we review the recent literature about the risk factors, diagnosis, treatment and prevention of fungal sepsis in these high risk infants.

Isolation, identification, and antimicrobial susceptibility of Clostridium perfringens isolates from acute necrotic enteritis of broiler chickens

The aim of this study was to isolate, identify and determine the antimicrobial susceptibility of Clostridium perfringens [CP] isolates from acute necrotic enteritis of broiler chickens. All broiler carcasses diagnosed as necrotic enteritis [NE] were sampled, subjected to microbial tests and 40 isolates were identified according to standard procedures. The antimicrobial susceptibility of CP isolates to 20 antibacterial agents was then determined. The results show widespread resistance among CP isolates. The most frequent resistance was observed to neomycin sulfate [87.5%], and then to lincomycin and tetracycline [both 80%]. No isolate was resistant to chloramphenicol and the least frequency of resistance was observed to vancomycin [10%], sulfamethoxazole+trimethoprim [17.5%], and penicillin [20%]. All isolates were multiple drug resistant types. There were 39 resistant patterns among the CP isolates, 95% of which were distributed in 38 resistant patterns. These multiple and variable resistance patterns observed among the CP isolates, even among different isolates from one farm, demonstrate a challenge for veterinarians in the field to choose the correct compound to combat the occurrence of NE