[Clinical and radiographical success of pulpotomy with mineral trioxide aggregate compared with formocresol in primary molars]

Formocresol is the common drug in pulpotomy of primary molars. In some studies it has been shown that, this material has the potentiality of some side-effects, so it is essential to find other alternatives. The aim of this study was to evaluate the clinical and radiographic success of mineral trioxide aggregate and formocresol. In this experimental study, 70 deciduous molars of children aged 4-8 years old were pulpotomized with mineral trioxide aggregate and formocresol. The clinical and radiographic follow up was done at 6, and 12 months. The data was analyzed by Fisher exact test. At the end of 12 months follow-up, success rate was 92.14% and 93.55% in formocresol and mineral trioxide aggregate group respectively. Based on the results of this study there was no significant difference in clinical and radiographical success between MTA and formocresol

[Histopathological evaluation of pulp changes after ferric sulfate and formocresol pulpotomy in primary teeth]

Formocresol is an inrtacanal medicament commonly used for pulpotomy in the primary dentition. Because of its toxic and carcinogenic potential, it has been challenged by other chemical treatments. The purpose of this study was to histologically assess the pulpal healing process in pulpotomized primary teeth, using two different agents: formocresol and ferric sulfate. A total of 16 primary cuspids [8 pairs] from 8 patients who were scheduled for orthodontic extraction were selected and randomly divided into 2 groups. One tooth from each pair of contralatcral teeth was assigned to either formocresol or ferric sulfate pulpotomy. Four pairs were extracted after 1 month and the other 4, after 2 months. Pulpal response was determined according to the degree of inflammation and extent of pulpal involvement. Dentinal bridge formation was also evaluated. The data were analyzed using Wilcoxon test. No significant difference was found between the two groups for inflammation, absecess, root resorption and dcntinal bridge formation. Necrosis was more extensive in the formocresol pulpotomy group [p<0.05]. Based on these results, formocresol can be substituted with ferric sulfate for pulpotomy of primary teeth

Estudo do potencial irritativo do formocresol em sua fórmula original, diluído a 1/5 e 1/10, na fase exsudativa do processo inflamatório / Study of the toxicity of formocresol in original formulation and diluted at 1/5 and 1/10, in exsudative phase of an inflamatory process

Os autores estudaram o potencial irritativo da substância formocresol em sua fórmula original e diluída a 1/5 e 1/10, na fase exsudativa do processo inflamatório, tendo como controle a soluçäo salina fisiológica. Utilizaram em seu trabalho trinta e seis ratos machos adultos, pesando entre 230 e 300 gramas. Duas horas após a depilaçäo da regiäo dorsal, injetaram-se intravenosamente 20 mg/kg de peso corporal de "Evans blue" a 2 por cento, inoculando-se imediatamente 0,1 ml das substâncias a serem testadas. Após tres horas os animais foram sacrificados, e realizou-se a retirada das peles, seccionando-as com vasador de 3 cm de diâmetro. Estas peles foram cortadas em pequenos fragmentos e os fragmentos colocados em formamida e levados à estufa à 45ºC por 72 horas. A seguir, procedeu-se à leitura no espectrofotômetro regulado a 620nn de comprimento de onda. Os resultados obtidos foram apresentados em D.O. e convertidos em transmitância aplicando-os aos critérios de avaliaçäo, preconizados por Nagem-Filho & Pereira, modificado por Ribeiro

Medicamentos usados em pulpotomias: hidróxido de cálcio, formocresol e glutaraldeído: uma revisäo da literatura / Medicaments used in pulpotomies: calcium hydroxide, formocresol and glutaraldehyde: a review of the literature

Consideraçöes a respeito dos medicamentos atualmente utilizados em pulpotomias, citando as vantagens, desvantagens e principais controvérsias quanto à aplicaçäo clínica

Evaluación clínica y radiográfica de molares temporales con pulpas necróticas, tratados con dos concentraciones de formocresol / Radiological and clinical evaluation of molars primary with pulpectomy procedures and formocresol treatment

El propósito de esta investigación fué evaluar, clínica y radiográficamente, molares temporales con pulpas necróticas, tratados con dos concentraciones de formocresol. Se realizaron 50 casos, de los cuales fueron finalmente evaluados 32. Se efectuaron 3 evaluaciones: la primera a los 3 meses, la segunda a los 6 meses y la tercera al año post-tratamineto. Se utilizaron dos formatos especialmente elaborados para anotar las condiciones iniciales de cada caso y las evaluaciones correspondientes. No hubo diferencia estadísticamente significativa en los resultados obtenidos con las dos concentraciones, aunque la reparación ósea se llevó a cabo más rapidamente en los casos tratados con la fórmula concentrada. El formocresol diluido (1/5), resultó satisfactorio para tratar molares temporales con pulpas necróticas, constituyendo un procedimiento sencillo, más seguro, economico y aplicable a todas las edades y niveles socio-económicos