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Indian J Exp Biol ; 2001 May; 39(5): 479-82
Artículo en Inglés | IMSEAR | ID: sea-62201

RESUMEN

Mentha extract (ME; 1 g/kg body wt) given orally for three consecutive days prior to whole body irradiation (8 Gy) showed modulation of activity of serum phosphatases in albino mice. Values of acid phosphatase activities were significantly higher in untreated irradiated group throughout the experiment. Irradiated animals pretreated with ME showed significant decline in acid phosphatase activity as compared to untreated irradiated animals at all autopsy intervals and attained normalcy at day 5. A marked decrease in serum alkaline phosphatase activity was recorded in both irradiated groups. However, in ME pretreated irradiated group, values of alkaline phosphatase activity remained significantly higher than untreated irradiated animals at all intervals and attained normalcy from day 5 onwards.


Asunto(s)
Fosfatasa Ácida/antagonistas & inhibidores , Fosfatasa Alcalina/antagonistas & inhibidores , Animales , Rayos gamma/efectos adversos , Cinética , Masculino , Mentha piperita , Ratones , Extractos Vegetales/farmacología , Protectores contra Radiación/farmacología
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