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An. bras. dermatol ; 93(1): 80-85, Jan.-Feb. 2018. tab, graf
Artículo en Inglés | LILACS | ID: biblio-887135

RESUMEN

Abstract: Orofacial granulomatosis is a nonspecific term that contains a wide variety of granulomatous entities, which share a clinical and histopathological presentation. It manifests as persistent or recurrent orofacial swelling, amongst other findings. Idiopathic orofacial granulomatosis, characterized by an absence of systemic granulomatous disease, is a diagnosis of exclusion. The main differential diagnosis is Crohn's disease. Its pathogenesis is unknown, however, it seems to be immune-mediated. Patch-test sensitivity to multiple allergens is well documented. Currently, therapeutic options consider restrictive diets, topical, intralesional, and systemic agents. First-line therapy is currently a matter of debate. We present a review of the value of diet therapy in this syndrome, along with two illustrative cases.


Asunto(s)
Humanos , Masculino , Adolescente , Adulto , Adulto Joven , Granulomatosis Orofacial/dietoterapia , Inmunoglobulina E/sangre , Pruebas Cutáneas , Granulomatosis Orofacial/diagnóstico , Granulomatosis Orofacial/patología , Mucosa Bucal/patología
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