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Indian J Physiol Pharmacol ; 1987 Jan-Mar; 31(1): 25-9
Artículo en Inglés | IMSEAR | ID: sea-108497

RESUMEN

'Arogyavardhini'-an indigenous formulation was evaluated for its hepatoprotective activity in rats, using two models of carbon tetrachloride (CCl4) hepatic damage, one simulating vital hepatitis and the other simulating fatty change. The protective effect was assessed from serum aspartate transaminase (AST) and alkaline phosphatase levels and from histopathological changes in liver. The results revealed that 'Arogyavardhini' (5 mg/100g, PO daily) was effective in minimizing the changes in serum levels of AST and alkaline phosphatase induced by CCI. The protective effect was also evident on histopathological examination.


Asunto(s)
Fosfatasa Alcalina/sangre , Animales , Aspartato Aminotransferasas/sangre , Intoxicación por Tetracloruro de Carbono/prevención & control , Combinación de Medicamentos/farmacología , Hígado Graso/prevención & control , Hepatitis Viral Animal/prevención & control , Hígado/efectos de los fármacos , Masculino , Medicina Ayurvédica , Metales/farmacología , Extractos Vegetales/farmacología , Ratas
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