RESUMEN
The study goals present an overview of Hospitalizations for Ambulatory Care Sensitive Conditions (ACSC) in Guarulhos, SP, from 2008 to 2012. This is an ecological study based on secondary data obtained from the Brazilian Hospital Information System, and supported by the Praxical Theory of Intervention of Collective Health Nursing. Applied descriptive statistics for analysis. It was observed that Guarulhos shows an upward trend in hospitalizations by ACSC (20% increase), the most frequent causes of heart failure (11.8%), cerebrovascular disease (10.6%) and angina (9.7%), most frequently in the age group ≥ 65years old, for both sexes. The results are similar to other Brazilian studies, but their analysis should extrapolate the biological limits and the supply of healthcare resources, focusing on the social determinants of the health-disease process. .
El estudio tuvo como objetivo proporcionar una visión general de las Hospitalizaciones por Condiciones Sensibles a la Atención Primaria (ICSAP) en Guarulhos, SP, en el período 2008-2012. Se trata de un estudio ecológico a partir de datos secundarios obtenidos a través del Sistema de Información Hospitalaria, y apoyado por la Teoría de Intervención Práxica de la Enfermería en Salud Colectiva. Se aplicó la estadística descriptiva para el análisis. Se observó que Guarulhos muestra una tendencia al alza en las hospitalizaciones por ICSAP (aumento del 20%), las causas más frecuentes de insuficiencia cardiaca (11,8%), enfermedad cerebrovascular (10,6%) y la angina (9,7% ), con mayor frecuencia en el grupo de edad ≥ 65 años para ambos sexos. Los resultados son similares a otros estudios brasileños, pero su análisis debe extrapolar los límites biológicos y el suministro de los recursos sanitarios, centrándose en los determinantes sociales del proceso salud-enfermedad. .
Objetivo Apresentar o panorama das Internações por Condições Sensíveis à Atenção Primária (ICSAP) no município de Guarulhos, SP, no período de 2008 a 2012. Método Estudo ecológico, com dados secundários obtidos via Sistema de Informações Hospitalares, sustentado pela Teoria de Intervenção Práxica da Enfermagem em Saúde Coletiva. Empregou-se estatística descritiva para análise. Resultados Observou-se que Guarulhos apresenta trajetória crescente nas internações por ICSAP (aumento de 20%), sendo as causas mais frequentes a insuficiência cardíaca (11,8%), as doenças cerebrovasculares (10,6%) e a angina (9,7%), com maior frequência na faixa etária ≥ 65 anos, para ambos os sexos. Conclusão Os resultados encontrados assemelham-se a outros estudos brasileiros, porém sua análise deve extrapolar os limites biológicos e a oferta de recursos assistenciais, atentando para as determinações sociais do processo saúde-doença. .
Asunto(s)
Animales , Masculino , Ratas , Medicamentos Herbarios Chinos/uso terapéutico , Fitoterapia , Lesiones Precancerosas/tratamiento farmacológico , Neoplasias Gástricas/tratamiento farmacológico , Mucosa Gástrica/irrigación sanguínea , Mucosa Gástrica/efectos de los fármacos , Mucosa Gástrica/patología , Hexosaminas/metabolismo , Malondialdehído/metabolismo , Lesiones Precancerosas/irrigación sanguínea , Lesiones Precancerosas/patología , Ratas Wistar , Neoplasias Gástricas/irrigación sanguínea , Neoplasias Gástricas/patologíaRESUMEN
Effect of two calcium channel blockers (CCBs) nifedipine and amlodipine, was studied on normal and steroid depressed wound healing in albino rats, using the dead space wound model. The drugs enhanced normal healing as evidenced by increase in tensile strength of 10 days old granulation tissue. There was neither a significant change in the hydroxyproline level (or collagen) nor a change in the glycosaminoglycan content in granulation tissue. However, lysyloxidase level was increased significantly. The increase in tensile strength could thus be attributed to better cross-linking and maturation of collagen rather than collagen synthesis per se. The drugs were also able to overcome steroid depressed wound healing. It is likely that the prohealing effects may be related to the improved antioxidant status too, since superoxide dismutase levels were observed to be higher in the CCB- treated animals.
Asunto(s)
Amlodipino/farmacología , Animales , Antioxidantes/farmacología , Bloqueadores de los Canales de Calcio/farmacología , Glicosaminoglicanos/metabolismo , Hexosaminas/metabolismo , Ácidos Hexurónicos/metabolismo , Hidroxiprolina/metabolismo , Masculino , Nifedipino/farmacología , Proteína-Lisina 6-Oxidasa/metabolismo , Ratas , Ratas Wistar , Esteroides/metabolismo , Superóxido Dismutasa/metabolismo , Resistencia a la Tracción , Vasodilatadores/farmacología , Cicatrización de Heridas/efectos de los fármacosRESUMEN
In the catfish H. fossilis, administration of testosterone (0.25, 0.5, 1 and 2 micrograms/g body weight for 20 days) during mid-preparatory phase (March) increased plasma testosterone, gonadosomatic index, seminal vesicle-somatic index and concentrations of total proteins, fructose and hexosamines in seminal vesicle (SV) and testis in a dose-related manner. In the lowest dosage (0.25 microgram) group, only the hexosamine and SV protein levels were significantly high. Glucose level decreased in a dose-related manner, the decrease being not significant in the 0.25 microgram group. The results indicate that testosterone stimulates SV and testicular secretions of total proteins, hexosamines and fructose in catfish. Decrease in glucose content suggests its conversion into fructose under testosterone stimulation.
Asunto(s)
Animales , Bagres/metabolismo , Fructosa/metabolismo , Glucosa/metabolismo , Hexosaminas/metabolismo , Masculino , Proteínas/metabolismo , Vesículas Seminales/efectos de los fármacos , Testículo/efectos de los fármacos , Testosterona/administración & dosificaciónRESUMEN
Levels of protein bound hexose, hexosamine and proteins in ethanol precipitate of the body fluid and protein bound hexose and proteins in the perchloric acid filtrate of the body fluid of the snail L. luteola which received a xenoplastic implant in its cephalopedal sinus, are determined. The significant increase in protein bound hexose in the ethanol precipitate of bodyfluid in recipient snail as compared to sham operated and control snails is interesting. The results are discussed in the light of what is known about glycoproteins and their role in invertebrate immunity.
Asunto(s)
Animales , Líquidos Corporales/metabolismo , Glicoproteínas/inmunología , Hexosaminas/metabolismo , Lymnaea/inmunología , Sustancias Macromoleculares , Trasplante HeterólogoRESUMEN
Shay rats and conscious rabbits were used to study the effect of sex hormones on gastric secretion. Daily injections of estradiol-di propionate and testosterone-propionate were given separately to each set of animals, while the control animals received solvent alone for the same duration of time. Estrogen inhibited gastric acid output but augmented the mucus secretion as evidenced by increased hexosamine and fucose contents; and testosterone had the reverse effects. The effect of estrogen was more potent that of testosterone. An inverse relationship between gastric acid and mucus secretion has been noted. Peptic activity varied independently of the acid output. These hormones seemed to vary the acid output by modifying the composition of mucus secretion.