Transition metal complexes of hydrazone derived from isonicotinic acid hydrazide

Hydrazones derived from isonicotinic acid hydrazide [INH] and a number of their transition metal complexes are well known for their antibacterial, antitumour and antitubercular activities[1]. Also, some hydrazones of INH have been used as analytical reagents[2], polymer-coatings, inks, pigments[3] and fluorescent materials[4]. Few studies have been made on those derived from alpha- and beta-diketones and their azo derivatives[5-7]. Copper complexes of benzeneazoacetylacetone isonicotionylhydrazone have been described[8]. In this paper, we describe the synthesis and characterization of transition metal complexes of orthohydroxybenzeneazoethylacetoacetate isonicontinoyl - hydrazone

Synthesis, spectral and magnetic studies of binuclear Mn [II], Co [II] and Cu [II] complexes with hydrazone ligands derived from 1,4-dihydrazinophthalazine

Binuclear Mn[II], Co[II], Ni[II] and Cu[II] complexes of some hydrazone derivatives were synthesized and characterized by elemental analysis, conductance measurements and IR spectra. The hydrazones behaved as monoanionic bidentate ligands. Electronic spectra and magnetic susceptibility measurements of the solid complexes indicated tetrahedral geometry around Co[II] and Mn[II] ions, octahedral geometry around Ni[II] and square planar the Cu[II] ion

Electrochemical behavior of the product of coupling of crotononitrile with aryldiazonium salts

It has been reported that compounds la-c couple with aromatic diazonium salts to yield the corresponding hydrazones 2a-c, which readily cyclize into the pyridazines 3a-c, c.f. Plate 1. However, Mittelbach [1] reported that at least the product of coupling component 1 c with aromatic diazonium salts would be 3 c, so that compound 2 c could have never been isolated. This led Mettelbach [1] to suggest that the coupling products assigned by Elnagdi et al. [2] as being of the types of compound 2 would be in fact related to compounds 3

Isatin isonicotinoyl hydrazone complexes of Zn, Cd and Hg

The Zn, Cd and Hg complexes of isatin isonicotinoyl hydrazone were prepared at two different pH. Their structures were confirmed by elemental analysis, IR, PMR spectroscopy and TG studies. Only hydrate bis complexes were obtained, which are insoluble in most organic solvents and have melting points above 270C. They have the formula [M[HL]2. Cl2]xH2O, however, the mercuric complex obtained from a solution of pH 10 has the formula HgL2.3H2O. X-ray diffraction patterns revealed less crystallinity for the Zn complex prepared at pH 10, than that obtained from neutral medium. The ligand and the Cd and Hg complexes are biologically active towards Gram +ve and Gram -ve bacteria, but the complexes of Zn are inactive