RESUMEN
Primary hypothyroidism and type 2 diabetes are both typically associated with the increased level of triglycerides. To date, there have been only a few case reports of type 2 diabetes patients with both type V hyperlipoproteinemia and eruptive xanthomas, but there have been no reports of hypothyroidism patients associated with eruptive xanthomas. We report here on a case of a 48-yr old female patient who was diagnosed with type 2 diabetes and primary hypothyroidism associated with both type V hyperlipoproteinemia and eruptive xanthomas. We found rouleaux formation of RBCs in peripheral blood smear, elevated TSH, and low free T4 level, and dyslipidemia (total cholesterol 18.1 mM/L, triglyceride 61.64 mM/L, HDL 3.0 mM/L, and LDL 2.54 mM/L). She has taken fenofibrate, levothyroxine, and oral hypoglycemic agent for 4 months. After treatment, both TSH level and lipid concentration returned to normal range, and her yellowish skin nodules have also disappeared.
Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Hipolipemiantes/uso terapéutico , Diabetes Mellitus Tipo 2/sangre , Agregación Eritrocitaria , Hiperlipidemias/sangre , Hiperlipoproteinemia Tipo V/sangre , Hipoglucemiantes/uso terapéutico , Hipotiroidismo/sangre , Fenofibrato/uso terapéutico , Enfermedades de la Piel/sangre , Tirotropina/sangre , Tiroxina/sangre , Resultado del Tratamiento , Xantomatosis/sangreRESUMEN
Los perfiles de los tipos clásicos mencionados pueden encontrarse en forma aislada o en diversas combinaciones. Muchas veces el perfil resulta limítrofe entre dos clasificaciones, siendo difícil incluirlo en uno de los dos tipos. Este problema se presenta en el 10%de las muestras