Características clínicas y OCT-SA de pacientes con síndrome de tracción iridiana asociado a desprendimiento de retina regmatógeno. Reporte de tres casos / Clinical features and AS-OCT of patients with iris retraction syndrome following rhegmatogenous retinal detachment. Report of three cases

Introducción: se presenta una serie de 3 casos de síndrome de retracción iridiana (SRI) asociados a desprendimiento de retina regmatógeno (DRR) y desprendimiento coroideo. Objetivo: dar a conocer las características clínicas y tomográficas de tres pacientes con SRI asociado a desprendimiento de retina regmatógeno. Diseño del estudio: serie de casos. Resumen del caso: tres pacientes que presentaron DRR asociado a SRI. El tiempo de evolución promedio fue de 21 días (15-30 días), 2 de los 3 pacientes tuvieron resolución del SRI posterior al inicio de midriáticos y antes de ser intervenidos por el desprendimiento de retina, y 2 tuvieron presencia de proliferación vitreoretiniana (PVR) a pesar del corto tiempo de evolución. Adicionalmente estos 2 pacientes cursaron con desprendimientos coroideos. Todos los pacientes tuvieron un buen resultado estructural, AV menor o igual a 20/400, no redesprendimientos ni recurrencias de SRI durante el seguimiento. Conclusión: ante un paciente con SRI en el cual no sea posible valorar polo posterior, se debe tener en cuenta el diagnóstico de desprendimiento de retina regmatógeno. El SRI puede considerarse como un factor de mal pronóstico en pacientes con desprendimiento de retina regmatógeno.

Background: to report a 3 cases series of patients with iris retraction syndrome (IRS). Objective: introduce the clinical and tomographic features of tree patients with IRS following RRD. Study design: case series. Case summary: three patients presented IRS following RRD. They presented with an average evolution of 21 days (15 to 30 days), 2 patients had resolution of the IRS after mydriatics and before receiving surgical treatment for retinal detacthment, and 2 had vitreoretinal proliferation despite the short time. Besides, these 2 patients had choroidal detachments discovered in the operating room. All patients had good structural outcomes, visual acuity less or equal than 20/400, no re-detachment of the retina and no recurrence of IRS during follow up. Conclusion: the presence of a retinal detachment should be suspected in a patient with IRS in which it´s not possible to assess the posterior pole, and it should be considered a bad prognostic factor if present.

Maculopatia hipotônica pós ciclodiálise traumática por arma de fogo / Hypotonic maculopathy post traumatic cyclodialysis with firearms

Resumo Um traumatismo ocular contuso pode gerar uma vasta gama de lesões intraoculares que são dependentes da quantidade de energia que o objeto transfere ao olho durante o impacto. As lesões da íris, malha trabecular e corpo ciliar podem repercutir na drenagem do humor aquoso. A ocorrência de uma ciclodiálise caracterizada pelo descolamento do corpo ciliar da parede escleral, criando uma comunicação entre a câmara anterior e o espaço supracoroidiano, pode provocar importante redução da pressão intraocular. Esta diminuição pressórica é a responsável pela ocorrência da maculopatia hipotônica que pode cursar com diminuição irreversível da acuidade visual. Não existe consenso na literatura sobre o tratamento das ciclodiálises. Neste relato, descrevemos um caso de ciclodiálise traumática pós impacto com projétil de arma de fogo tratada com aplicação de laser de argônio.

Abstract Blunt eye trauma can generate a wide range of intraocular lesions that are dependent on the amount of energy the object transfers to the eye during the impact. Lesions of the iris, trabecular meshwork and ciliary body may influence aqueous humor drainage. The cyclodialysis which is characterized by the detachment of ciliary body from the scleral wall, creating a communication between the anterior chamber to supracoroid space, can cause a several reduction of intraocular pressure. This pressure decrease is responsible for the occurrence of hypotonic maculopathy which may induce a severe impact on visual acuity. There is no consensus in the literature about cyclodialysis treatment. In this report, we describe a case of traumatic cyclodialysis after impact with a firearm projectile treated with argon laser photocoagulation.

Desprendimiento coroideo tardío poscirugía de catarata con facoemulsificación en pacientes glaucomatosos / Late choroidal detachment after cataract surgery with phacoemulsification in glaucoma patients

El desprendimiento coroideo es un factor predisponente y causa de hipotonía ocular marcada. Se describen dos pacientes operados de glaucoma por técnica de trabeculectomía simple, con más de 5 años de evolución, bajo régimen medicamentoso de timolol 0,5 por ciento colirio, 2 veces por día, intervenidos de catarata senil con técnica de facoemulsificación sin complicaciones trans ni posquirúrgicas inmediatas, quienes presentan disminución brusca de la agudeza visual a dos meses de la cirugía, por desprendimiento coroideo sin pérdida de cámara anterior, asociado a hipotonía ocular y maculopatía. Se analizan las posibles causas y se impone tratamiento adecuado. Finalmente se logra una evolución satisfactoria(AU)

Choroidal detachment is a cause of and predisposing factor for marked ocular hypotony. A description is provided of two patients undergoing glaucoma surgery by simple trabeculectomy technique, with more than five years of evolution, under drug treatment with 0.5 percent timolol collyrium twice daily, intervened for senile cataract with phacoemulsification technique, without any intra- or immediate post-operative complications, who presented with sudden visual acuity reduction two months after surgery, due to choroidal detachment without anterior chamber loss, associated to ocular hypotony and maculopathy. The possible causes are analyzed and appropriate treatment is indicated. Satisfactory evolution is finally achieved(AU)

Management of Postoperative Ocular Hypotony after Tube Surgery by Stenting Using Two 5-0 Nylon Threads

No abstract available.

Algorithm approach for revision surgery following late-onset bleb complications after trabeculectomy: long-term follow-up / Algoritmo de abordagem para cirurgia de revisão nas complicações da bolha de início tardio após trabeculectomia: acompanhamento de longo prazo

ABSTRACT Purpose: The aim of this study was to introduce a reproducible algorithm for the surgical management of late-onset (>2 months) bleb complications after trabeculectomy with mitomycin C. Methods: We performed a retrospective review of eyes treated using a reproducible algorithm approach by a single surgeon for the surgical management of late-onset bleb complications from July 2006 to April 2014. Exclusion criteria were bleb revision with less than 3 months of follow-up or bleb revision combined with other glaucoma procedures at the time of surgery. Success was evaluated using the Kaplan-Meier survival method and defined as achieving all of the following criteria: primary surgery indication resolved, no additional surgery required for decreasing the intraocular pressure (IOP), and IOP of ≥6 mmHg and ≤18 mmHg. Results: Twenty-three eyes from 20 patients were evaluated. Indications for bleb revision were hypotonic maculopathy (47.8%), bleb leak (30.4%), and dysesthetic bleb (21.7%). The overall primary outcome success rate calculated using the Kaplan-Meier survival method was 65.2% at 48 months. When the IOP target was changed to ≤15 mmHg, the bleb survival rate was 47.8% at 48 months. At the most recent postoperative visit, 95.7% of eyes had an IOP of ≤15 mmHg and 56.5% were being treated with an average of one medication per eye. One eye (4.3%) required a second bleb revision for persistent hypotony and two eyes required glaucoma surgery to reduce IOP during follow-up. Conclusions: An algorithm approach for the surgical management of late-onset bleb complications with a success rate similar to those reported in specialized literature is proposed. Randomized trials are needed to confirm the best surgical approach.

RESUMO Objetivo: Descrever um algoritmo reprodutível para o tratamento cirúrgico das complicações da bolha de início tardio (>2 meses) após trabeculectomia com mitomicina-C. Métodos: Revisão retrospectiva de olhos que foram submetidos a um algoritmo reprodutível para o tratamento cirúrgico das complicações da bolha de início tardio por um único cirurgião, de julho de 2006 a abril de 2014. Os critérios de exclusão foram revisão de bolha com menos de 3 meses de seguimento ou revisão de bolha combinado com outro procedimento antiglaucomatoso no momento da cirurgia. O sucesso foi avaliado pelo método de sobrevida de Kaplan-Meier e definidos como ter atingido todos os seguintes critérios: indicação de cirurgia primária resolvido, nenhuma cirurgia adicional necessária para diminuir a pressão intraocular (IOP), IOP ≥6 mmHg e ≤18 mmHg. Resultados: Vinte e três olhos de 20 pacientes foram incluídos. Indicações para revisão bolha foram maculopatia hipotônica (47,8%), extravasamento da bolha (30,4%) e bolha elevada (21,7%). A taxa de sucesso do resultado primário global calculada pelo método de sobrevivência de Kaplan-Meier foi de 65,2% aos 48 meses. Quando a IOP foi diminuída para ≤15mmHg, a taxa de sobrevivência bolha foi de 47,8% em 48 meses. Na visita pós-operatória mais recente, 95,7% dos olhos apresentavam PIO ≤15mmHg e 56,5% estavam sob tratamento com uma média de um medicamento por olho. Um olho (4,3%) necessitou de uma segunda revisão da bolha para hipotonia persistente e dois olhos necessitaram cirurgia de antiglaucomatosa para reduzir a IOP durante o seguimento. Conclusões: Um algoritmo de abordagem para o tratamento cirúrgico das complicações tardias da bolha com uma taxa de sucesso semelhante aos relatados na literatura especializada é proposto. Ensaios clínicos randomizados são necessários para confirmar a melhor abordagem cirúrgica.

Enxerto de retalho escleral de doador como tratamento definitivo de maculopatia hipotônica pós trabeculectomia / Scleral patch as a definitive treatment for hypotonic maculopathy after trabeculectomy

RESUMO Paciente do sexo feminino, portadora de glaucoma juvenil sem controle clínico adequado, foi submetida à trabeculectomia com mitomicina C, após a qual, desenvolveu hipotensão ocular refratária às medidas conservadoras, evoluindo com um quadro de maculopatia hipotônica. Foi realizado um implante de enxerto de retalho escleral de doador sobre a fístula, com resolução do quadro e ganho de acuidade visual. A enxertia de retalho escleral de doador mostrou-se uma terapia adequada para correção da hipotensão ocular por bolha hiperfiltrante pós trabeculectomia. O cirurgião deve considerar o emprego dessa técnica ao programar a revisão destes casos.

ABSTRACT A female patient with juvenile glaucoma without clinical control underwent a trabeculectomy with mitomycin C, and developed eye hypotension which did not respond to conservative treatment, with subsequent hypotonic maculopathy. The patient was treated using a scleral patch provided by a donor above the fistula, which improved intraocular pressure and visual acuity. The use of the scleral patch above the fistula seems an adequate therapy to treat ocular hypotension due to the over-filtering trabeculectomy bubble. The surgeon should consider this technique when planning surgical solutions for such cases.

Direct cyclopexy surgery for post-traumatic cyclodialysis with persistent hypotony: ultrasound biomicroscopic evaluation / Ciclopexia direta em ciclodiálise pós-traumática com hipotonia ocular persistente -acompanhamento por biomicroscopia ultrassônica (UBM)

Cyclodialysis is a relatively rare condition usually caused by ocular injury; however, it can also be caused iatrogenically during intraocular surgery. Hypotony maculopathy is the most important complication and the primary reason for visual loss. Clinical diagnosis using gonioscopy may be difficult, and ultrasound biomicroscopy (UBM) can be an alternative. There are different kinds of treatments, and the optimal one remains controversial. Here we describe a case of traumatic cyclodialysis with persistent ocular hypotony treated by direct cyclopexy, as illustrated by UBM performed before and after surgery.

Ciclodiálise é uma condição relativamente rara, geralmente devido a um trauma ocular, mas também pode ser causada iatrogenicamente como consequência de cirurgia intraocular. A maculopatia hipotônica é a complicação mais importante e a principal razão para a perda visual nessa situação. O diagnóstico clínico por gonioscopia pode ser difícil e a biomicroscopia ultrassônica (UBM) pode ser uma alternativa. Existem diferentes tipos de tratamentos e algumas controvérsias sobre a melhor opção. Neste relato, nós descrevemos um caso de ciclodiálise traumática com hipotonia ocular persistente tratado por cyclopexia direta avaliado por UBM antes e depois da cirurgia.

Transient Hypotony after Silicone Oil Removal in Rhegmatogenous Retinal Detachment

PURPOSE: To determine the risk factors for transient hypotony after silicone oil removal in rhegmatogenous retinal detachment and to analyze changes in intraocular pressure and visual acuity after silicone oil removal. METHODS: The medical records of 54 eyes of 52 patients who underwent pars plana vitrectomy, silicone oil tamponade followed by silicone oil removal due to rhegmatogenous retinal detachment, were reviewed. RESULTS: The incidence of transient hypotony after silicone oil removal was 18.5%. Young age (p = 0.011) and axial length (p = 0.002) were risk factors for transient hypotony based on univariate analysis. In multivariate analysis, axial length longer than 26 mm was the only risk factor for transient hypotony (p = 0.005). Seven hypotony patients recovered to normal intraocular pressure spontaneously within 2 weeks. In 2 patients, intraocular pressure was normalized after intravitreal injection of C3F8 gas and 1 patient recovered after a balanced salt solution injection into the anterior chamber. Two weeks after silicone oil removal, there was no significant difference in intraocular pressure between the hypotony group and normal intraocular pressure group. Additionally, there was no statistically significant difference in best corrected visual acuity between the 2 groups after 2 weeks. CONCLUSIONS: Although transient hypotony after silicone oil removal in rhegmatogenous retinal detachment was frequently observed in the present study, the final best corrected visual acuity and intraocular pressure was not always affected. Ocular hypotony should be examined thoroughly in the early postoperative period.

Cyclocryotherapy and Intravitreal Gas Tamponade of a Chronic Cyclodialysis Cleft: Case Report

PURPOSE: To report a case of chronic hypotony maculopathy caused by traumatic cyclodialysis cleft and treated with 20% sulfur hexafluoride (SF6) gas tamponade with cyclocryotherapy. CASE SUMMARY: A 39-year-old woman with a history of blunt trauma developed a unilateral chronic ocular hypotony in her left eye. She was treated with topical atropine sulphate 1% for 2 months. Three years later, she was referred to our clinic for evaluation and treatment of persistent hypotony. The intraocular pressure (IOP) was 4 mm Hg and the best corrected visual acuity was 0.4. B-scan echography revealed a choroidal effusion and fundus examination showed choroidal detachment and macular folds. Gonioscopy examination revealed cyclodialysis cleft from the direction of 7 o'clock to 11 o'clock. A single bubble of SF6 20% (0.4 cc) was injected into the vitreous cavity and transconjunctival cyclocryotherapy was performed under retrobulbar anesthesia. Six months later, the IOP was 12 mm Hg and the best corrected visual acuity was 1.0. B-scan echograpy and fundus examination showed the disappearance of the choroidal effusion. CONCLUSIONS: Gas tamponade with cyclocryotherapy may be useful in cases of cyclodialysis cleft that failed to respond to medical therapy.

Diagnosis and treatment of hyperfiltering blebs / Diagnóstico e tratamento de bolsas fistulantes hiperfuncionantes

PURPOSE: To report on a new treatment for hyperfiltering bleb as well as its diagnostic criteria. METHODS: Twenty eyes with hypotony due to hyperfiltering bleb caused by trabeculectomy with mitomicin C were treated with bleb resection. The diagnosis of hyperfiltering bleb followed these criteria: intraocular pressure lower than six mmHg (Goldmann tonometer); no inflammation in the anterior segment; presence of an elevated and/or diffuse and avascular bleb with or without microcysts; negative Seidel test; no ciliochoroidal detachment found with ultrasound biomicroscopy. We registered the following data pre and post operatively: type of glaucoma, visual acuity, bleb aspect and fundoscopic findings. A successful resolution of hypotony was achieved when intraocular pressure ranged from six to 14 mmHg with or without antiglaucomatous medication. RESULTS: At a minimum follow-up of 19 months ocular hypotony had been reversed in all eyes. At the last exam, intraocular pressure varied from eight to 14 mmHg in 18 (90 percent) eyes; 12 (66.7 percent) eyes had no medication and six (33.3 percent) used antiglaucomatous medication. In two (10 percent) eyes, another trabeculectomy was necessary to control intraocular pressure. Hypotonic maculopathy developed preoperatively in seven eyes and was reversed after bleb resection. Visual acuity improved in 15 (75 percent) eyes but did not change in five (25 percent). CONCLUSION: Bleb resection is a safe and adequate treatment for ocular hypotony due to hyperfiltering bleb. It also restores vision in a considerable number of patients. The diagnosis of hyperfiltering bleb must follow rigorous criteria.

OBJETIVO: Relatar os resultados de uma nova técnica para o tratamento de bolsa hiperfuncionante, assim como seus critérios diagnósticos. MÉTODOS: Vinte olhos (20 pacientes) com hipotonia ocular causada por bolsa hiperfuncionante após trabeculectomia com mitomicina C foram tratados com ressecção da bolsa. O diagnóstico de bolsa hiperfuncionante obedeceu aos seguintes critérios: pressão intraocular inferior a seis mmHg (tonometria de Goldmann); ausência de inflamação do segmento anterior ocular; presença de bolsa fistulante elevada e/ou difusa e avascular com ou sem microcistos; teste de Seidel negativo; ausência de descolamento ciliocoroidiano ao exame de UBM. Foram registrados no pré e pós-operatório: o tipo de glaucoma, a acuidade visual, o aspecto da bolsa e os achados oftalmoscópicos. A resolução da hipotonia foi alcançada quando a pressão intraocular variou de seis a 14 mmHg sem ou sob medicação tópica antiglaucomatosa. RESULTADOS: No seguimento mínimo de 19 meses, a hipotonia ocular foi revertida nos 20 olhos. No último exame, a pressão intraocular variou de oito a 14 mmHg em 18 (90 por cento) olhos; 12 (66,7 por cento) olhos sem medicação e seis (33,3 por cento) olhos sob medicação tópica. Em dois (20 por cento) olhos foi necessário nova trabeculetomia para controle da pressão intraocular. Maculopatia hipotônica foi diagnosticada no pré-operatório em sete olhos e foi revertida em todos eles após a ressecção da bolsa. A acuidade visual melhorou em 15 (75 por cento) olhos e não se alterou em cinco (25 por cento). CONCLUSÃO: A ressecção da bolsa é eficaz no tratamento da hipotonia ocular consequente a sua hiperfunção. Esse procedimento também recupera a visão num considerável número de pacientes. O diagnóstico de bolsa hiperfuncionante deve obedecer a critérios rigorosos.

Sarcoma intraocular felino associado à phthisis bulbi / Feline intraocular sarcoma associated with phthisis bulbi

Two cases of feline intraocular sarcoma were reported in stray cats that presented blindness and hypotonia of the affected eye for years before the tumor development. Phthisis bulbi, a final stage of a severe inflammation of the eye, is frequently unmonitored because eyes are blind, small, opaque, and not painful. Yet, this report shows that monitoring and early enucleation of eyes of cats with phthisis bulbi are important and should be considered as a treatment option, because feline intraocular sarcoma is an aggressive tumor that significantly decreases live expectancy.

Relatam-se dois casos de sarcoma ocular em gatos que apresentavam cegueira e hipotonia nos olhos afetados por anos antes do crescimento neoplásico. Phthisis bulbi, que é o estágio final de um processo inflamatório ocular intenso, geralmente não é monitorado por tratar-se de um olho cego, pequeno e não doloroso. O relato demonstra que o monitoramento e a enucleação precoce de olhos em phthisis bulbi são importantes e devem ser considerados como opções de tratamento, porque o sarcoma intra-ocular é agressivo e pode diminuir significativamente a expectativa de vida.

The Recurrent Submacular Hemorrhage after Removal of Sub-Internal Limiting Membrane Hemorrhage with Retinal Arterial Macroaneurysm

PURPOSE: To report a case of a recurrent macular hemorrhage that developed after surgical removal of the internal limiting membrane (ILM) for subintimal hemorrhage due to retinal macroaneurysm. CASE SUMMARY: A 75-year-old female was admitted to the hospital complaining of decreased vision in the left eye which had started 3 weeks previously. The best corrected visual acuity (BCVA) of the right and left eye was 0.7 and 0.03, respectively. The intraocular pressure (IOP) of the right and left eye was 10 mm Hg and 12 mm Hg, respectively. On the fundus examination, macular preretinal and subretinal hemorrhage was observed and a diagnosis of retinal arterial macroaneurym of the inferonasal major artery was made. Vitrectomy was performed. After indocyanine green dye staining, the sub-ILM hemorrhage was treated with removal of the ILM. At postoperative day 3, the annular chorioretinal folds were observed due to the hypotony (4 mm Hg). However, the absence of leakage was confirmed through the sclerotomy site. At postoperative day 8, recurrent submacular hemorrhage occurred and the hemorrhage was observed to have spread after intravitreal C3F8 gas injection and when the patient was placed in the prone position. At postoperative 4 months, the hemorrhage that had invaded the macular area was completely resolved. The BCVA was 0.3, respectively. CONCLUSIONS: When removing a sub-ILM hemorrhage due to retinal macroaneurysm, recurrent hemorrhage can occur especially in a patient with ocular hypotony, as in the present case report. Physicians should be aware of this possibility and the proper treatment the condition requires.

Influence of Application Methods on Results of Contact Transscleral Nd:YAG Laser Cyclophotocoagulation

PURPOSE: To examine the influence of irradiation methods on the long-term results of contact transscleral Nd:YAG laser cyclophotocoagulation and to evaluate the factors that affect changes in intraocular pressure (IOP) and occurrence of ocular hypotony after cyclophotocoagulation. METHODS: In this retrospective study, 36 refractory glaucomatous eyes of 36 patients were observed for at least one year after a cyclophotocoagulation procedure. Contact transscleral Nd:YAG laser cyclophotocoagulation was performed with 7 to 10 Watts of power, a duration of 0.7 seconds, with one or two rows, and ranges of either greater or less than 180 degrees. The change in IOP, the success rate of the procedure, and the occurrence rate of hypotony were analyzed with regard to the methods of cyclophotocoagulation. RESULTS: In this series of patients with refractory glaucoma, the final IOP and success rate were not significantly influenced by the laser application method or by the total energy used. The eyes with ocular hypotony showed significantly decreased IOP one year after cyclophotocoagulation when compared with eyes without ocular hypotony. The IOP percent reduction in the patients with ocular hypotony tended to decrease more rapidly than did that of the patients without hypotony, beginning three months after the operation. CONCLUSIONS: The application methods of cyclophotocoagulation appear to have no significant influence on success rate, IOP or ocular hypotony rate. The percent reduction in IOP was higher in the hypotony group, including during the early postoperative periods.

Uso de membrana amniótica en el tratamiento de pterigion recidivante, en pacientes intervenidos quirúrgicamente en el Centro Nacional de Oftalmología julio 2007-noviembre 2008 / Use of amniotic membrane in treating recurrent pterygium in patients who underwent surgery at the National Center of Ophthalmology July 2007-November 2008

Se realizó un estudio descriptivo, longitudinal, prospectivo en el Centro Nacional de Oftalmología, durante el período Julio 2007 a Noviembre 2008 con el objetivo de determinar la eficacia de la membrana amniótica en el tratamiento quirúrgico del pterigión recidivante. El Universo lo constituyeron todos los pacientes que asistieron a consulta por pterigión recidivante en el período Julio 2007 – Noviembre 2008 en el Centro Nacional de Oftalmología. La Muestra estuvo conformada por 43 pacientes que tenían historia de pterigión recidivante de 1 año o mas de evolución en el mismo período. Entre los resultados más importantes se destacan que la mayoría de los pacientes tenían entre 36 y 55 años, femeninos, de procedencia urbana, 1 cirugía de pterigión previa y de 1 a 3 años de haber sido operados. El corte evaluativo se realizó cuando todos los pacientes tenían al menos 3 meses de intervención. 4 pacientes presentaron recidiva (9.3%), teniendo estos las características de ser masculinos, del grupo etáreo de 36 a 55 años y 1 cirugía previa. Se concluyó que el uso de membrana amniótica como tratamiento de pterigión recidivante es un método seguro y eficaz en un 90.7%. Se recomendó la implementación del uso de membrana amniótica en pacientes con pterigión recidivante, a fin de reducir el porcentaje de recidivas...

Effect of Excision of Avascular Bleb and Advancement of Adjacent Conjunctiva for Treatment of Hypotony

PURPOSE: To evaluate the efficacy of excision of avascular bleb and advancement of adjacent conjunctiva (EBAC) for treatment of hypotony after trabeculectomy with mitomycin C (MMC). METHODS: Fifteen patients (17 eyes) who received EBAC for correction of hypotony between September 1996 and October 2008 were reviewed retrospectively. The main outcomes were intraocular pressure (IOP) and postoperative complications. RESULTS: Hypotony (IOP <6 mmHg) of eight eyes (47.1%, seven patients) was caused by bleb perforation. Of these, two eyes (two patients) had a history of trauma. Hypotony appeared at 33.9+/-30.8 months, and EBAC was performed at 48.2+/-35.3 months after trabeculectomy with MMC. The mean follow-up period was 38.3+/-29.8 months. The qualified success rate of EBAC was 100% at 51 months after EBAC, and the complete success rate of EBAC was 76.5% at six months and 70.6% at 51 months, as determined by Kaplan-Meier analysis. Post-EBAC complications included blepharoptosis in four eyes (23.5%) and bleb perforation in one (5.9%). The blepharoptosis resolved within one month after EBAC in two patients. However, in the other patients, mild blepharoptosis remained at 17 and 22 months postoperatively. CONCLUSIONS: EBAC was found to be an effective method for treatment of hypotony after trabeculectomy with MMC, and postoperative blepharoptosis was a major complication.

Perfluoro-N-octane as Postoperative Vitreous Substitutes in Retinal Detachment: A Case Report

PURPOSE: To report a case of retinal detachment with a giant retinal tear, which was treated with perfluorocarbon liquid as an intraocular substitute. CASE SUMMARY: A 37-year-old woman with a dislocated lens and a giant retinal tear underwent vitrectomy and lensectomy and was instructed to maintain a supine position after the operation. Perfluorocarbon liquid (Perfluoro-N-octane, C8F18) was used as a substitute in the vitreous cavity for 17 days. After 17 days, the perfluorocarbon liquid was removed and intraocular lens scleral fixation was performed. After removal of the perfluorocarbon liquid, the corneal endothelium was stable without other complications (including corneal edema, elevated intraocular pressure, ocular hypotony, macular pucker), and the best corrected visual acuity after intraocular lens scleral fixation was 0.4. CONCLUSIONS: Perfluorocarbon liquid is a useful surgical material in patients with a dislocated lens and retinal detachment with a giant retinal tear who have difficulty maintaining a prone position.

Macular Hole as a Risk Factor of Choroidal Detachment in Rhegmatogenous Retinal Detachment

PURPOSE: Choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD) is a rare, but serious condition, which makes the prognosis worse. Previously reported risk factors for CD in RRD patients include high myopia, aphakia, pseudophakia, and advanced age. However, macular hole has not been discussed as an important factor in increasing the risk of CD in RRD patients. The purpose of this study was to evaluate macular hole as a risk factor for CD in eyes evidencing RRD. METHODS: The medical records of 480 patients with primary RRD were reviewed. We compared the CD incidence among the RRD patients in accordance with the presence or absence of macular holes. The relationship between gender, age, presence of systemic disease, refractive errors, lens status, intraocular pressure and the development of CD were also analyzed. RESULTS: The incidence (4/21 eyes, 19.0%) of CD in the RRD with macular hole was significantly higher than that (7/459 eyes, 1.5%) observed in the RRD without macular hole (p=0.010). The preoperative intraocular pressure (mean+/-SD; 2.5+/-1.3 mmHg) in the RRD with CD and macular hole was significantly lower than that (7.4+/-4.4 mmHg) observed in the cases of RRD with CD without macular hole (p=0.035). The eyes complicated by CD evidenced a higher prevalence of diabetes mellitus (p=0.024) than was observed in the eyes without CD. CONCLUSIONS: The retinal detachment combined with macular hole creates a predisposition toward the development of profound hypotony and CD.

Detecção de maculopatia hipotônica subclínica pelo OCT III após cirurgia filtrante / Detection of subclinical hypotony maculopathy with OCT III after filtration surgery

OBJETIVO: Detectar possíveis sinais de maculopatia hipotônica subclínica por meio da OCT III em pacientes submetidos à cirurgia filtrante. MÉTODOS: Pacientes que realizaram procedimento cirúrgico filtrante com pressão intra-ocular menor que 9 mmHg submeteram-se ao exame OCT III. RESULTADOS: Sete (87,50 por cento) pacientes apresentaram diagnóstico prévio de glaucoma crônico simples e 1 (12,50 por cento) de glaucoma agudo de ângulo fechado. Apenas duas pacientes (25,00 por cento) apresentaram maculopatia hipotônica detectada pela OCT III. CONCLUSÃO: A OCT III parece ser um bom método diagnóstico de maculopatia hipotônica subclínica em pacientes submetidos à cirurgia filtrante convencional.

PURPOSE: To detect nondiagnostic hypotony maculopathy by OCT III after filtration surgery. METHODS: After surgery, patients with intraocular pressure less than 9 mmHg were submitted to OCT III examination. RESULTS: Seven (87.50 percent) patients with previous diagnosis of open angle glaucoma and one (12.50 percent) of them with acute angle closure glaucoma. Two patients (25.00 percent) presented hypotony maculopathy on OCT III examination. CONCLUSION: OCT III examination seems to be a good diagnostic method to detect subclinical hypotony maculopathy after filtration surgery.

Results of post-trabeculectomy bleb revision using conjunctiva

To evaluate and compare the results of different surgical methods for post-trabeculectomy bleb revision at Labbafinejad Medical Center, Tehran-Iran, from 1999 to 2003. This study was conducted on all patients who underwent post-trabeculectomy bleb revision due to hypotony [intraocular pressure [IOP] less than 6 mmHg] or bleb leakage. Surgical methods were: conjunctival advancement, rotational conjunctival flap and free conjunctival graft. Bleb revision was performed in the cases of bleb leakage if the bleb hole was greater than 1 mm or leakage could not be controlled within 1 to 2 weeks of conservative treatment. Bleb revision was performed in eyes with hypotony in cases with cataract development or progression or hypotony maculopathy or iridocorneal adhesion. Surgical success was defined as IOP between 6-21 mmHg with a maximum of 2 topical antiglaucoma medications and discontinuation of leakage. Twenty-seven eyes of 27 patients [17 male, 10 female] with mean age of 37.8 +/- 15.2 years [9-37 years] were studied. Indication for surgery was bleb leakage in 22 cases [81.5%] and hypotonous maculopathy in 5 cases [18.5%]. Mean IOP was 4.4 +/- 1.04 mmHg preoperatively and 13.00 +/- 1.29 mmHg postoperatively. [P< 0.001] Mean visual acuity was 0.9 LogMAR [20/160] before surgery and reached 0.6 LogMAR [20/80] after bleb revision. [P<0.002] Mean cup/disc ratio was 0.7 preoperatively which remained unchanged postoperatively. Conjunctival advancement was performed in 18 cases [success rate = 72.2%], rotational conjunctival flap in 6 cases [success rate= 66.7%] and free conjunctival graft in 3 cases [success rate= 66.7%]. [P=0.73] Bleb revision was repeated in 2 cases due to continuous leakage. Mitomycin-C [MMC] and 5-fluorouracil had been used during primary trabeculectomy in 62% and 7.6% of cases, respectively. In 19.6% of cases surgery was done without using antimetabolites and usage of antimetabolites was unknown in 11%. The average time between primary trabeculectomy and bleb leakage or hypotonia was 17 months in cases with prior use of MMC and 52 months in the cases with no antimetabolite usage. [P<0.05] Post-trabeculectomy bleb revision using conjunctiva seems to be a successful method for control of leakage and prevention of complications of hypotony