Insulinoma canino: relato de caso / Canine insulinoma: case reports

O insulinoma é um tumor das células ß do pâncreas, que têm a função de produzir e secretar insulina e, geralmente são malignos em cães. O presente trabalho descreve o diagnóstico e o manejo terapêutico de três casos de insulinoma. Os sinais clínicos dos animais relatados variaram de acordo com a severidade e a duração da hipoglicemia. O diagnóstico presuntivo se deu através dos sinais clínicos e da dosagem de insulina sérica no momento de mais intensa hipoglicemia e, o diagnóstico definitivo foi obtido por meio de exame histopatológico nos três casos relatados. O tratamento realizado variou de acordo com a intensidade dos sinais clínicos.(AU)

Insulinoma is a tumor of the ß cells of the pancreas, which have the function to produce and secrete insulin and are usually malignant in dogs. This paper describes the diagnosis and therapeutic management of three cases of insulinoma. The clinical signs reported animals varied according to the severity and duration of hypoglycemia. The presumptive diagnosis was based on clinical signs and serum insulin dosage at the time of hypoglycemia and more intense, the definitive diagnosis was made by histopathological examination in three of the reported cases. The treatment was varied according to the severity of clinical signs.(AU)

Diagnosis and management of hypoglycaemia due to pancreatic insulin-secreting neoplasia in a German shepherd dog

A 7-year-old castrated male German shepherd dog was presented with a 10-day history of intermittent lethargy, weakness and episodic seizures. Laboratory findings after admission revealed hypoglycaemia and hyperinsulinaemia. Provisional diagnosis of insulinoma was made based on the presence of concurrent hypoglycaemia and elevated insulin level. In exploratory laparotomy a small nodular mass was detected on the pancreas. Other abdominal organs were normal in gross inspection. The mass was removed surgically. Histopathology of the excised pancreatic nodule confirmed the diagnosis of insulinoma. The dog became seizure free following the surgical operation