Successful prophyloxix of clostridium perfringens endophthalmitis

Our report describes a 30 year-old man, who sustained a penetrating injury with an intraocular foreign body. The patient underwent pars plana vitrectomy and removal of the intraocular foreign body. A vitreous biopsy culture grew Clostridium perfringens, The postoperative course was complicated by a fibrinous reaction in the anterior chamber that was controlled by frequent streoid eye drops. Two months after the procedure, visual acuity was 20/60 with no evidence of infection. The excellent outcome in this case supports prompt vitrectomy intervention and the removal of acute retained intraocular foreign bodies in the prophylactic treatment of C. perfringens endophthalmitis

Endophthalmitis caused by anaerobic bacteria.

A retrospective analysis of 22 patients who underwent pars plana vitrectomy for endophthalmitis and had culture-proven anaerobic bacteria, was done. Elimination of infection with attached retina and recovery of ambulatory vision > or = 2/60 were considered as anatomic success and functional success, respectively. Mean follow-up period was 12.7 months (range, 2 to 48 months). Anatomic success was attained in 14 (63.6%) eyes and functional success in 12 (54.6%) eyes. A poor preoperative visual acuity was found to be associated with poor functional outcome (p < 0.046). In endophthalmitis, a routine anaerobic culture of intraocular specimen is recommended.