Desenvolvimento de competências para evacuação aeromédica em emergências e desastres: protocolo de revisão de escopo / Skill development for aeromedical evacuation in emergencies and disasters: a scoping review protocol

OBJETIVO: mapear a produção técnico-científica sobre as competências necessárias para o desenvolvimento de evacuações aeromédicas em situações de emergências e desastres envolvendo agentes químicos, biológicos, radiológicos e nucleares. MÉTODO: protocolo de revisão de escopo. A elaboração deste protocolo foi baseada nas recomendações do Instituto Joanna Briggs, atendendo às recomendações do Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Este protocolo orientará o processo de identificação de fontes de informação, extração de dados e análise de resultados, a partir da necessidade de dar suporte à análise das ações de capacitação de equipes de saúde frente às demandas clínicas e gerenciais a serem criteriosamente observadas em tais situações.

OBJECTIVE: to map the technical-scientific production on the skills necessary for aeromedical evacuation in emergency and disaster situations involving chemical, biological, radiological, and nuclear agents. METHOD: scoping review protocol. The elaboration of this protocol was based on the Joanna Briggs Institute's recommendations, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). This protocol will guide the identification of the sources of information, data extraction, and the analysis of the results based on the need to support the analysis of training actions for health teams facing clinical and managerial demands that must be carefully considered in such situations.

Evaluation of ionizing radiation as a risk factor for the incidence of breast cancer: long-term analysis after the cesium-137 accident in Goiânia, Brazil. An ecological study

ABSTRACT BACKGROUND: The largest radiological accident to occur in any urban area happened in Goiânia, Brazil, in 1987. OBJECTIVE: To evaluate the association between breast cancer incidence and ionizing radiation levels. DESIGN AND SETTING: Ecological study among residents of the city of Goiânia, Brazil. METHODS: The central region of Goiânia, with seven major sources of contamination from cesium-137, was defined as the study area. The addresses of women diagnosed with breast cancer were identified between 2001 and 2010. The data were geographically referenced and, using census data, the annual averages of crude incidence rates were estimated. The existence of clusters of new cases was ascertained by means of the Moran index. Correlations of radiometric measurements with the incidence were assessed using unconditional linear regression. RESULTS: A total of 4,105 new cases were identified, of which 2,233 were in the study area, and of these, 1,286 (57.59%) were georeferenced. The gross rates of total and referenced cases were 102.91 and 71.86/100,000 women, respectively. These were close to the average for Brazilian state capitals, which is 79.37/100,000 women. The cluster analysis showed slight correlations in three small sets of census tracts, but these were far from the sources of contamination. The scatter plot of points and the R2 value close to zero indicated that there was no association between the variables. CONCLUSION: This study reinforces the hypothesis that the ionizing radiation levels to which women living in Goiânia are now exposed to are not associated with the onset of new cases of breast cancer.

A mineração de urânio em questão: análise da comunicação pública das Indústrias Nucleares do Brasil (INB) em Caetité, Bahia / Questioning uranium mining: an analysis of the public communication stated by Indústrias Nucleares do Brasil (INB) in Caetité, Bahia / La minería de uranio en cuestión: un análisis de la comunicación pública transmitida por la INB (Indústrias Nucleares do Brasil) en Caetité, Bahia

O objetivo deste artigo é discutir, através de análise de conteúdo, as estratégias de comunicação pública adotadas pelas Indústrias Nucleares do Brasil no 'Espaço INB', um centro de informações localizado na cidade baiana de Caetité, onde a empresa realiza a mineração e o beneficiamento de urânio. Desde que foram iniciadas, essas atividades levantaram inúmeras suspeitas de danos ambientais e problemas de saúde pública. Diante disso, buscamos compreender como a INB se posiciona diante dessas suspeitas e se relaciona com as populações atingidas por suas atividades. De acordo com nosso argumento, ao adotar uma postura que denominamos tecnoentusiasta e tecnocrática, a empresa dificulta um debate público aberto e descentralizado sobre as controvérsias em torno da mineração de urânio

This article aims to use the content analysis to discuss the public communication stated by the 'Espaço INB', an information center managed by Indústrias Nucleares do Brasil located in the city of Caetité ­ BA, where the company mines and processes uranium. Since INB started its activities in Caetité, several suspicions of environmental damage and public health problems emerged. Thus, we analyze how INB responds to these suspicions and relates to the populations affected by its activities. We argue that INB adopts an attitude that we call techno-enthusiastic and technocratic, hindering an open public and decentralized debate about the controversies surrounding uranium mining.

El objetivo de este artículo es discutir, a través del análisis de contenido, la comunicación pública transmitida por el 'Espaço INB', un centro de información administrado por Indústrias Nucleares do Brasil ubicado en la ciudad de Caetité/Bahia, donde la empresa hace la mínería y el procesamiento del uranio. Desde que comenzaron, estas actividades han generado numerosas sospechas de daños ambientales y problemas de salud pública. Por eso, analizamos como el INB contesta estas sospechas y se relaciona con las poblaciones afectadas por sus actividades. Argumentamos que el INB adopta una actitud que llamamos tecno-entusiasta y tecnocrática, lo que dificulta un debate público abierto y descentralizado sobre las controversias respecto a la minería de uranio.

Systemic Arterial Hypertension in Patients Exposed to Cesium-137 in Goiânia-GO: Prevalence Study / Hipertensão Arterial Sistêmica em Pacientes Expostos ao Césio-137 em Goiânia-GO: Estudo de Prevalência

Abstract Background: Systemic Arterial Hypertension (SAH) in the Brazilian population, in populations not exposed to Césio-137, presents a prevalence of 28% nationwide. However, in the group of radioactivity victims, these values are unknown. Objective: To analyze the prevalence of hypertension in patients exposed to Cesium-137 in Goiânia, enrolled in the Sistema de Monitoramento dos Radioacidentados (SISRAD) (Radioactivtity Victims Monitoring System) of the Centro de Assistência aos Radioacidentados (C.A.R.A) (Assistence Center for Radioactivity Victims). Methods: This is a descriptive, observational cross-sectional epidemiological study carried out in Goiânia-Goiás, from August 2013 to October 2014, with a group of patients enrolled in the Sistema de Monitoramento dos Radioacidentados (SISRAD) of the Centro de Assistência a Radioacidentados (C.A.R.A.). A total of 102 radioactive patients were divided into two groups: group 1 with 40 and group 2 with 62 participants. A field survey was conducted with a closed and semi-structured questionnaire in which the following contexts were addressed: sociodemographic profile, life habits and personal background. A database was created using the Google Forms application from the Google Web technologies company. The duly collected and stored data were imported and analyzed in the statistical software SPSS, version 21. Results: The prevalence of SAH reached a total of 25% (12 individuals) of the 48 interviewees, 50% of women (24) and 50% of men (24), of which 22.9% (11) of the radioactivity victims revealed to be smokers. Conclusion: The prevalence of SAH in the radioactivity victims population is similar to that of the population in general.

Resumo Fundamentos: A Hipertensão Arterial Sistêmica (HAS) na população brasileira, em populações não expostas ao Césio-137, apresenta prevalência de 28% em âmbito nacional. Porém, no grupo de radioacidentados, esses valores são desconhecidos. Objetivo: Analisar a prevalência da HAS em pacientes expostos ao Césio-137 ocorrido em Goiânia, cadastrados no Sistema de Monitoramento dos Radioacidentados (SISRAD) do Centro de Assistência aos Radioacidentados (C.A.R.A). Métodos: Estudo epidemiológico do tipo descritivo, observacional de caráter transversal realizado em Goiânia-Goiás, no período de agosto de 2013 a outubro de 2014, com grupo de pacientes cadastrados no Sistema de Monitoramento dos Radioacidentados (SISRAD) do Centro de Assistência aos Radioacidentados (C.A.R.A). Participaram da pesquisa 48 radioacidentados de um total de 102 que foram subdivididos em dois grupos: grupo 1 com 40 e o grupo 2 com 62 participantes. Realizou-se uma pesquisa de campo com questionário fechado e semi-estruturado em que foram abordados os seguintes contextos: perfil sociodemográfico, hábitos de vida e antecedentes pessoais. Criou-se um banco de dados utilizando-se o aplicativo Google Forms, da empresa de tecnologias na Web Google. Os dados devidamente coletados e armazenados foram importados e analisados no software estatístico SPSS, versão 21. Resultados: Dos 48 entrevistados a prevalência de HAS atingiu um total 25% deles (12 indivíduos), sendo 50% de mulheres (24) e 50% de homens (24), dentre estes, 22,9% (11) dos radioacidentados revelaram ser tabagistas. Conclusão: A prevalência de HAS na população de radioacidentados se manifesta de forma semelhante ao da população em geral.

Radiation exposure and thyroid cancer: a review

ABSTRACT The association between radiation exposure and the occurrence of thyroid cancer has been well documented, and the two main risk factors for the development of a thyroid cancer are the radiation dose delivered to the thyroid gland and the age at exposure. The risk increases after exposure to a mean dose of more than 0.05-0.1 Gy (50-100mGy). The risk is more important during childhood and decreases with increased age at exposure, being low in adults. After exposure, the minimum latency period before the appearance of thyroid cancers is 5 to 10 years. Papillary carcinoma (PTC) is the most frequent form of thyroid carcinoma diagnosed after radiation exposure, with a higher prevalence of the solid subtype in young children with a short latency period and of the classical subtype in cases with a longer latency period after exposure. Molecular alterations, including intra-chromosomal rearrangements, are frequently found. Among them, RET/PTC rearrangements are the most frequent. Current research is directed on the mechanism of genetic alterations induced by radiation and on a molecular signature that can identify the origin of thyroid carcinoma after a known or suspected exposure to radiation.

The radiation protection role of heparin-SOD conjugate in irradiated mice

ABSTRACT Heparin-SOD conjugate (Hep-SOD) was prepared by modifying Cu,Zn-SOD with heparin. An acute radiation-induced mouse injury model was constructed to study the radiation protection effects of Hep-SOD conjugate. Fifty-six mice were randomly divided into seven groups: (I) normal control group; (II) irradiated control group; (III) positive control group (amifostine group, 300 mg/kg); (IV) SOD group (35000 U/kg); (V) high dosage of Hep-SOD group (70000 U/kg); (VI) medium dosage of Hep-SOD group (35000 U/kg); (VII) low dosage of Hep-SOD group (17500 U/kg). Drugs were intraperitoneally injected into each mouse 1 h before radiation except for the normal control group. All the irradiated groups were irradiated with 6 Gy. Organ indices, haematopoietic function indices, peripheral blood cells, liver function test, oxidative stress state and pathological observation were detected to study the effects of Hep-SOD on irradiated mice. Results showed that bone marrow suppression of irradiated mice could be reduced when treated by Hep-SOD before radiation. Oxidative stress detection and pathological observation of the liver and intestine showed that the damage caused by radiation was relieved when mice were treated with Hep-SOD before radiation. This study shows a new direction to prevent organisms from the damage caused by radiation.

Boletim Epidemiológico resumido 2017: radioacidente Césio 137 - 30 anos / Summary Epidemiological Bulletin 2017: Cesium 137 radio accident - 30 years

O Boletim Epidemiológico resumido constitui um instrumento de informação objetivo, com dados sobre a mortalidade e a incidência cumulativa de transtornos de saúde sofridos pelos radioacidentados dos grupos I e II e seus filhos, desde o acidente radiológico, ocorrido em 27 de setembro de 1987, até 31 de julho de 2017, perfazendo quase 30 anos. Para o grupo III, as informações são relativas ao período de cinco anos, de agosto de 2012 a julho de 2017. Também há uma descrição dos atendimentos prestados pela Superintendência Leide das Neves (SULEIDE) e pelo Centro de Assistência aos Radioacidentados (CARA), por especialidade, desde 2008.

The summary Epidemiological Bulletin is an objective information tool, with data on mortality and the cumulative incidence of health disorders suffered by radio accident victims in groups I and II and their children, since the radiological accident, which occurred on September 27, 1987, until July 31, 2017, making it almost 30 years old. For group III, the information is related to the five-year period, from August 2012 to July 2017. There is also a description of the services provided by the Leide das Neves Superintendence (SULEIDE) and by the Assistance Center for Radio Injuries (CARA), by specialty, since 2008.

Characteristics of Emergency Medical Service Provider Responded Chemical, Biological, Radiological, and Nuclear Incidents: Pilot Analysis of National Emergency Medical Service Rescue Records

PURPOSE: The aim of this study was to evaluate the characteristics of Emergency Medical Service (EMS) provider responded chemical, biological, radiological, and nuclear (CBRN) incidents in Korea. METHODS: Nationwide EMS rescue records from Jan 2012 to Dec 2014 were analyzed. All EMS rescue records were integrated according to the unique accident ID. Cases related to animal rescue, hive removal, and suicide-related were excluded. CBRN-associated keywords were extracted by literature review and pilot survey. In-depth review of cases containing CBRN-associated keywords in the activity summary were conducted by trained emergency medical technicians, and predefined information was abstracted. Descriptive analyses were performed to characterize the EMS provider responded CBRN incidents. RESULTS: A total of 1,571,293 cases were included, and 1,335,205 cases had a unique accident ID; 515,417 cases were excluded because of their association with animal rescue, hive removal, and suicide attempts; 19,663 cases contained CBRN-associated keywords in the activity summary, and in-depth review identified 1,862 cases as CBRN incidents. Among them 1,856 cases were chemical incidents, and 6 cases were radiological incidents; 144 cases were resulted to victims. In chemical incidents, ammonia, hydrogen chloride, sulfuric acid, hydrogen fluoride, and nitric acid were the top 5 toxic substances. In chemical incidents with victims, the proportion of explosion/implosion, and suffocation in sealed space was more prevalent than chemical incidents without victims. Median scene time of all CBRN incidents was 41 minutes (interquartile range 18.0-57.0). CONCLUSION: We evaluated the characteristics of CBRN incidents responded by EMS in Korea.

Is the Linear No-Threshold Dose-Response Paradigm Still Necessary for the Assessment of Health Effects of Low Dose Radiation?

Inevitable human exposure to ionizing radiation from man-made sources has been increased with the proceeding of human civilization and consequently public concerns focus on the possible risk to human health. Moreover, Fukushima nuclear power plant accidents after the 2011 East-Japan earthquake and tsunami has brought the great fear and anxiety for the exposure of radiation at low levels, even much lower levels similar to natural background. Health effects of low dose radiation less than 100 mSv have been debated whether they are beneficial or detrimental because sample sizes were not large enough to allow epidemiological detection of excess effects and there was lack of consistency among the available experimental data. We have reviewed an extensive literature on the low dose radiation effects in both radiation biology and epidemiology, and highlighted some of the controversies therein. This article could provide a reasonable view of utilizing radiation for human life and responding to the public questions about radiation risk. In addition, it suggests the necessity of integrated studies of radiobiology and epidemiology at the national level in order to collect more systematic and profound information about health effects of low dose radiation.

Reconstructive dosimetry for cutaneous radiation syndrome

According to the International Atomic Energy Agency (IAEA), a relatively significant number of radiological accidents have occurred in recent years mainly because of the practices referred to as potentially high-risk activities, such as radiotherapy, large irradiators and industrial radiography, especially in gammagraphy assays. In some instances, severe injuries have occurred in exposed persons due to high radiation doses. In industrial radiography, 80 cases involving a total of 120 radiation workers, 110 members of the public including 12 deaths have been recorded up to 2014. Radiological accidents in industrial practices in Brazil have mainly resulted in development of cutaneous radiation syndrome (CRS) in hands and fingers. Brazilian data include 5 serious cases related to industrial gammagraphy, affecting 7 radiation workers and 19 members of the public; however, none of them were fatal. Some methods of reconstructive dosimetry have been used to estimate the radiation dose to assist in prescribing medical treatment. The type and development of cutaneous manifestations in the exposed areas of a person is the first achievable gross dose estimation. This review article presents the state-of-the-art reconstructive dosimetry methods enabling estimation of local radiation doses and provides guidelines for medical handling of the exposed individuals. The review also presents the Chilean and Brazilian radiological accident cases to highlight the importance of reconstructive dosimetry.

Emergency Medical Services in Disasters / 한양의대학술지

Disasters, or mass casualty incidents, occurring in modern history differ from those occurring in even the recent past. In previous times, disasters were mostly the result of natural causes such as earthquakes or floods. Currently, multiple casualty incidents are often the result of human actions such as vehicular accidents involving many vehicles with multiple operators, passengers and collateral victims, terror attacks and acts of war, radiation accidents, toxic chemical releases, and pandemic infectious agent exposures. Especially, events involving accidental and intentional exposures of chemical, biological, radiological/nuclear materials, often abbreviated as CBR or CBRN events present unique challenges to the healthcare system in caring for the victims. In these mass casualty incidents, a fully comprehensive, coordinated team response involving many different components of the community healthcare system need to be mobilized to effectively meet the modern challenge of CBRN events. Necessary components of a modern emergency response include training for prompt triage, decontamination, detoxification, emergency medical treatment, as well as providing appropriate transport to the proper medical treatment facility. Meeting these challenges requires maintaining ongoing communications between agencies charged with meeting the disaster to allow acquisition of information and location for the patients, transfer the information to both the Central Medical Emergency Response Center and the designated hospital. While sharing this information was problematic in the past, modern wireless communications and information technologies provide convenient means for the rapid sharing of important patient data and current situational details. Finally, improving modern disaster response requires the development of a disaster response plan, ongoing training in implementing the plan including disaster scenario simulation, and budgeting to acquire the necessary equipment involved for the emergency response personnel to meet the presenting crisis.

Indicadores citogenéticos para la identificación de exposición a radiación ionizante en humanos / Cytogenetic indicators for the identification of ionizing radiation exposure in humans

La biodosimetría citogenética se aplica en la evaluación médica de las personas involucradas en situaciones radiológicas anormales, con el fin de evaluar las dosis recibidas, el peligro inminente para la salud y aplicar los tratamientos médicos más adecuados. Además, contribuye al esclarecimiento de sucesos cuando existen dudas respecto a los resultados de la dosimetría física por dosímetros defectuosos, no calibrados o ausentes. Es el método más preciso de dosimetría biológica, ya que existe una relación matemática que permite calcular la dosis, establecer el grado de homogenidad de la exposición y, en caso de exposiciones no homogéneas, establecer la fracción del cuerpo irradiada y la dosis que recibió esa fracción mediante la cuantificación del número y tipos de aberraciones cromos¢micas y de micronúcleos y su distribución en los linfocitos de la sangre periférica. Para este análisis se establecen las relaciones dosis-efecto y un sistema automatizado para el cálculo de las dosis de radiación recibidas. Actualmente se está desarrollando un proyecto conjunto Universidad de Costa Rica-Hospital San Juan de Dios, con el objetivo de explorar los efectos cromosómicos de la radiación, en pacientes expuestos por razones el objetivo de explorar los efectos cromosómicos de la radiación, en pacientes expuestos por razones terapéuticas y atendidos en este hospital. De igual modo, se hará la curva de calibración dosis-respuesta in vitro para rayos gama y se validar  mediante la intercomparación con el Laboratorio de Dosimetría Citogenética de Centro para la Protección e Higiene de las Radiaciones de Cuba...

Prolonged expression of senescence markers in mice exposed to gamma-irradiation

Although ionizing radiation is known to induce cellular senescence in vitro and in vivo, its long-term in vivo effects are not well defined. In this study, we examined the prolonged expression of senescence markers in mice irradiated with single or fractionated doses. C57BL/6 female mice were exposed to 5 Gy of gamma-rays in single or 5, 10, 25 fractions. At 2, 4, and 6 months after irradiation, senescence markers including mitochondrial DNA (mtDNA) common deletion, p21, and senescence-associated beta-galactosidase (SA beta-gal) were monitored in the lung, liver, and kidney. Increases of mtDNA deletion were detected in the lung, liver, and kidney of irradiated groups. p21 expression and SA beta-gal staining were also increased in the irradiated groups compared to the non-irradiated control group. Increases of senescence markers persisted up to 6 months after irradiation. Additionally, the extent of mtDNA deletion and the numbers of SA beta-gal positive cells were greater as the number of radiation fractions increased. In conclusion, our results showed that ionizing radiation, especially that delivered in fractions, can cause the persistent upregulation of senescence marker expression in vivo. This should be considered when dealing with chronic normal tissue injuries caused by radiation therapy or radiation accidents.

Pulmonary disorder and present nuclear denotation: a brief summary

There are many health effects caused by leaked radiation from damaged reactors of a nuclear power plant. However, the effect on pulmonary system is not reported much. Focusing on the present nuclear denotation crisis in Japan, it is wise to review on the specific issue of pulmonary disorder and nuclear denotation. Several disorders of interest, including malignancy and non-malignancy disorders, are mentioned in the literature

Radioactivity and radiation hazard assessment of Cauvery River, Tamilnadu, India

Natural radiation is constantly present in the environment and is emitted from a variety of natural and artificial sources. It affects human body and environment. The activity concentrations of [238]U, [232]Th and [40]K have been determined by Gamma ray spectrometer with an HPGe detector in sediments of Cauvery River, Tamilnadu, India. The absorbed dose rate, radium equivalent concentration, external [Hex] and internal [Hin] hazardous indices are calculated from criteria formula and compared with the international recommended limits. The radioactive heat production rate and activity concentration index are also calculated. The observed dose rate measurements from ERDM [Environmental Radiation Dosi Meter] at 1m above the ground level at each site of the both rivers are measured and correlated with calculated absorbed dose rate. From the various parameters and correlation between them, the Cauvery River does not pose a radiological hazard except the site no. 21, 22, 23, 30, 31 and 35

Measuring gamma -ray dose of terrestrial samples using beta - gamma spectrometry

The existence of some radionuclides in soil and some building materials produce a beta - gamma radiation field, which in some regions the exposure of these radionuclides to human is high. The air-absorbed dose, indoor and outdoor annual effective dose of soil and some building material samples [ceramic, granite, gypsum, etc.]. The samples were collected from 35 different regions in the northwest of Iran were calculated. Specific activity of natural radionuclides [226]Ra, [232]Th and [40]K were measured by using a beta - gamma spectrometer consisted of NaI[Tl] and organic scintillators. The analysis of measured spectra was based on maximum likelihood estimation. The calculated data were compared with world's mean values. It is found that the specific activity of 40K ranges from 573.8 to 1392 Bqkg[-1], for [232]Th ranges from 6 to 54.6 Bqkg[-1] and for [226]Ra ranges from and 5.1 to 36.2 Bqkg-1. In some regions, the concentrations of natural radionuclides [[40]K, [232]Th, [226]Ra] were higher than standard level. Experimental results related to specific activity, indoor and outdoor annual effective doses of [226]Ra, [232]Th and [40]K revealed that radionuclide concentration in soil and some building material samples of some regions of northwest of Iran are of some radiological importance

Ionizing Radiation-induced Diseases in Korea

Radiation risk has become well known through epidemiological studies of clinically or occupationally exposed populations, animal experiments, and in vitro studies; however, the study of radiation related or induced disease has been limited in Korea. This study is to find the level of occupational radiation exposure for various kinds of accidents, compensated occupational diseases, related studies, and estimations on future occupational disease risks. Research data of related institutions were additionally investigated. About 67% of 62,553 radiation workers had no exposure or less than 1.2 mSv per year. The 5 reported cases on radiation accident patients in Korea occurred during nondestructive testing. According to the recent rapid increase in the number of workers exposed to radiation, a higher social recognition of cancer, and an increasing cancer mortality rate, it is expected that occupational disease compensation will rapidly increase as well. Therefore, it is important to develop scientific and objective decision methods, such as probability of causation and screening dose in the establishment of an exposure and health surveillance system.

Production of a datolite-based heavy concrete for shielding nuclear reactors and megavoltage radiotherapy rooms

Biological shielding of nuclear reactors has always been a great concern and decreasing the complexity and expense of these installations is of great interest. In this study, we used datolite and galena [DaGa] minerals for production of a high performance heavy concrete. Datolite and galena minerals which can be found in many parts of Iran were used in the concrete mix design. To measure the gamma radiation attenuation of the DaGa concrete samples, they were exposed to both narrow and wide beams of gamma rays emitted from a cobalt-60 radiotherapy unit. An Am-Be neutron source was used for assessing the shielding properties of the samples against neutrons. To test the compression strengths, both types of concrete mixes [DaGa and ordinary concrete] were investigated. The concrete samples had a density of 4420-4650 kg/m[3] compared to that of ordinary concrete [2300-2500 kg/m[3]] or barite high density concrete [up to 3500 kg/m[3]]. The measured half value layer thickness of the DaGa concrete samples for cobalt-60 gamma rays was much less than that of ordinary concrete [2.56 cm compared to 6.0 cm]. Furthermore, the galena concrete samples had a significantly higher compressive strength as well as 20% more neutron absorption. The DaGa concrete samples showed good shielding/ engineering properties in comparison with other reported samples made, using high-density materials other than depleted uranium. It is also more economic than the high-density concretes. DaGa concrete may be a suitable option for shielding nuclear reactors and megavoltage radiotherapy rooms

Effects of early liothyronine consumption after radioiodine therapy on accumulated dose and exposure rate in patients with thyroid carcinoma

Patients administered with a therapeutic dose of 131I for thyroid cancer treatment are potential sources of unacceptably high radiation exposure to other individuals, particularly the patient's immediate family members. The aim of this study is to investigate effects of early liothyronine consumption after radio-iodine therapy on accumulated dose and exposure rate in patients with thyroid carcinoma. This study was also undertaken to provide specific guidelines as to when 131I treated thyroid cancer patients may be safe to resume close contact with their family members. Forty patients treated postoperatively by 131I for the first time were studied. These patients were divided into two groups of twenty [group 1 with liothyronine and group 2 without liothyronine]. The administered dose was 100 mCi for all patients. Thermoluminescent dosimeter chips were placed on the neck of the patients to measure thyroid dose. Liothyronine was administered 24 h after iodine therapy. Accumulated dose was measured at 12, 24, 36 and 48 h after iodine therapy. Exposure rate was also measured at 0.5, 1 and 1.5 meters from the patient's body axis with Geiger-Muller detectors at discharge time and one week later. The findings indicated that liothyronine reduces accumulated dose of thyroid and stimulates rapid washout from the body after 48 h. The patient exposure rate was significantly higher in group 2 during or one week following discharge from the hospital. This study shows that liothyronine consumption decreases the exposure rate of patients at discharge time to the levels lower than that recommended by regulatory organizations