Transplante autólogo de músculo ocular extrínseco para tratamento cirúrgico de estrabismos sensoriais grandes / Autologous graft of extraocular muscle to treat large angle sensory strabismus

RESUMO Apresenta-se uma série de 13 casos de pacientes com estrabismo sensorial de grande ângulo submetidos à técnica cirúrgica de autotransplante da musculatura ocular extrínseca. Foi realizada a técnica de recuo-ressecção dos músculos retos horizontais, e o retalho retirado do músculo ressecado foi suturado ao músculo enfraquecido como expansor autólogo. Foram avaliadas seis exotropias e sete esotropias, com desvios médios de 75 (70-90) dioptrias prismáticas (DP). Houve melhora significativa dos desvios no pós-operatório, sendo a média pós-operatória de 10,07 dioptrias prismáticas (ortotropia a 35DP). Somente um dos casos evoluiu com inversão do desvio após procedimento cirúrgico.

ABSTRACT We report 13 cases of large angle sensory strabismus treated with autologous graft of extraocular muscle. Recession-resection procedure of the horizontal rectus muscles was performed, and the flap from the resected muscle was sutured to the weakened muscle as an autologous expander. Six cases of exotropia and seven of esotropia, with mean prism diopter deviation of 75 (range of 70-90). There was significant improvement in the postoperative deviation, and mean prism diopter of 10.07 (range of no deviation to 35). Only one patient progressed with inverted misalignment after the surgical procedure.

Recession-Resection Surgery Augmented with Botulinum Toxin A Chemodenervation for Paralytic Horizontal Strabismus

In this case series study, we assessed the effects of recession-resection surgery augmented with botulinum toxin A chemodenervation for patients with chronic paralytic horizontal strabismus. In addition, we compared these effects with those of full tendon transposition (FTT) augmented with posterior intermuscular suture (PIMS). Ten patients who underwent strabismus surgery due to paralytic horizontal strabismus were retrospectively reviewed. They received a recession-resection surgery augmented with botulinum toxin A chemodenervation (type I surgery) or a FTT augmented with PIMS (type II surgery). The preoperative angle of deviation (AOD) and postoperative improvement in AOD were compared according to the type of procedure. The preoperative AOD was 60.00 +/- 28.50 prism diopters (PD) for type I surgery and 68.00 +/- 27.06 PD for type II (p = 0.421). Improvement in AOD was 53.20 +/- 25.01 PD for type I surgery and 44.20 +/- 18.74 PD for type II (p = 0.548). Recession-resection surgery augmented with botulinum toxin A chemodenervation is a concise and effective procedure for treating paralytic horizontal strabismus.

Autologous grafting of extraocular muscles: experimental study in rabbits

OBJETIVO: Avaliar a viabilidade do uso de segmentos de músculos oculares extrínsecos como expansores de tendões musculares. MÉTODOS: Vinte e nove coelhos tiveram seu músculo reto superior esquerdo ressecado e o fragmento de cada um foi transplantado para o reto superior contralateral (grupo-teste). Então, o reto superior esquerdo foi reinserido na esclera (grupo-controle). Os animais foram então examinados em diversos períodos pós-operatórios, até os seus sacrifícios, para que se avaliasse o desenrolar dessa técnica cirúrgica. RESULTADOS: A hiperemia foi maior entre os testes. A secreção e a atrofia muscular foram mínimas nos dois grupos. Houve maior presença de fibrose no grupo-teste, mas não tão expressiva a ponto de inviabilizar os efeitos da cirurgia. Esses músculos também se romperam mais facilmente do que os do grupo-controle, porém, a força de rompimento foi sempre bem maior do que aquela presente numa contração muscular normal. CONCLUSÕES: A técnica de transplante autólogo homotópico de músculos oculares extrínsecos provou ser confiável e eficaz, para o alongamento muscular.

Anterior Transposition of Inferior Oblique Muscle for Treatment of Unilateral Superior Oblique Muscle Palsy with Inferior Oblique Muscle Overaction

Although many weakening procedures for the inferior oblique muscle have been advocated, there is some controversy as to the most beneficial procedure for weakening overacting inferior oblique muscles. This study was undertaken to determine if unilateral anterior transposition of the inferior oblique muscle alone could be a safe and effective procedure for treating unilateral superior oblique palsy from the perspective of hypertropia, inferior oblique overaction, and abnormal head posture. The records of 33 patients, who underwent anterior transposition of the inferior oblique muscle for unilateral superior oblique palsy at our institution between Jan 1995 and Dec 2002, were retrospectively reviewed. The average preoperative inferior oblique overaction was 2.3 +/-0.64, and the hypertropia in the primary position was 12.3 +/-7.69 prism diopter (PD). Twenty-six patients showed head tilt to the opposite direction preoperatively. After the anterior transposition of the inferior oblique, inferior oblique overaction was diminished in 32 patients (97%). Twenty-six out of 33 patients (79%) had no hypertropia in the primary position at last postoperative assessment. Of the 26 patients with head tilt before surgery, 21 patients (81%) achieved full correction after surgery. Satisfactory results were obtained in most of the patients in our study with the exception of three patients who required additional surgery. No patient demonstrated postoperative hypotropia in the primary position. None of the patients noticed elevation deficiency or lower lid elevation. The anterior transposition of the inferior oblique was found to be safe and effective for treating superior oblique palsy with secondary overaction of the inferior oblique muscle.

Prevençäo de aderências músculo-esclerais: um estudo experimental / Prevention of muscle-scleral adhesion: an experimental study

Os autores estudaram, em cirurgia de estrabismo, a funçäo antiadesiva de três materiais sintéticos (Golfoam, Silicone e Cianoacrilato). O modelo experimental utilizado foi o transplante autólogo homotópico de músculo extra-ocular em coelhos. O Gelfoam foi o material que apresentou os melhores resultados