RESUMEN
The effect of HD-03 a herbal preparation was studied on galactosamine (400 mg/kg b.wt., i.p.) induced hepatotoxicity in rats. Animals were pre-treated for 14 days with HD-03 and compared against untreated group for SGPT, SGOT, serum bilirubin and liver glycogen. Histopathology of liver lobes was considered to evaluate the extent of hepatic injury induced by galactosamine. These were reversed by HD-03 pre-treatment. HD-03 provided convincing evidence of hepatoprotection against galactosamine induced hapatotoxicity.
Asunto(s)
Magnoliopsida/uso terapéutico , Animales , Conductos Biliares/patología , Femenino , Galactosamina , Enfermedad Hepática Inducida por Sustancias y Drogas/metabolismo , Hígado/patología , Pruebas de Función Hepática , Masculino , Necrosis , Fitoterapia , Extractos Vegetales/uso terapéutico , Ratas , Ratas WistarRESUMEN
Se determinó la actividad de 29 especies de angiospermas frente a Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus, Candida albicans, Aspergillus niger, Fusarium oxisporum y Mucor sp. Las especies Cavendishia bracterata, Piper aduncum, Aragoa abietina y Piper bogotensis presentaron la mayor actividad antibacteriana y Chromolaena odorata mostró actividad antifúngica y antibacterina