RESUMEN
Congenital medulloblastoma is a rare brain tumor that appears in less than 1% of pediatric patients. Congenital medulloblastoma has a poor prognosis and should be suspected in patients with clinical manifestations of hyporeactivity, slow suction reflexes, and the presence of hydrocephalus. Herein we present the case of a 12-day-old female newborn who developed non-communicative hydrocephalus, hyporeactivity, and hyporeflexia. Magnetic resonance imaging of her brain showed a heterogeneous and cystic mass on the posterior cranial fossa. A suboccipital craniotomy was performed. The histopathologic analysis reported a congenital medulloblastoma. She remained in hospital until her death at 112 days old. This is one of the first case reports with clinical-radiological and pathological documentation. Awareness of this diagnosis can allow prenatal intervention, rendering a better prognosis. This case report exemplifies the importance of good prenatal follow-up.
Asunto(s)
Humanos , Femenino , Embarazo , Recién Nacido , Neoplasias Cerebelosas/congénito , Meduloblastoma/congénito , Diagnóstico Prenatal , Resultado FatalRESUMEN
We report here on a neonate with congenital cerebellar mixed germ cell tumor, and this initially presented as cerebellar hemorrhage. Postnatal cranial ultrasonography revealed an echogenic cerebellar mass that exhibited the signal characteristics of hemorrhage rather than tumor on MR images. The short-term follow-up images also suggested a resolving cerebellar hemorrhage. One month later, the neonate developed vomiting. A second set of MR images demonstrated an enlarged mass that exhibited changed signal intensity at the same site, which suggested a neoplasm. Histological examination after the surgical resection revealed a mixed germ cell tumor.
Asunto(s)
Femenino , Humanos , Recién Nacido , Enfermedades Cerebelosas/etiología , Neoplasias Cerebelosas/congénito , Hemorragia Cerebral/etiología , Imagen por Resonancia Magnética , Neoplasias de Células Germinales y Embrionarias/congénitoRESUMEN
Lipomas intracranianos säo raros, geralmente sendo achado de autópsia. Situam-se na linha média, mais frequentemente de localizaçäo central. Podem ocorrer desde a infância até a vida adulta. Muitos dos "lipomas", na verdade säo associados a lesöes hamartomatosas ou, mesmo, a neoplasias como os meduloblastomas do cerebelo. Relatamos e discutimos um caso de lipoma de cerebelo, achado de autópsia de um recém-nascido prematuro.