Primary multifocal anaplastic large cell lymphoma with eyelid involvement: a case report / Linfoma anaplásico de grandes células primário multifocal com envolvimento de pálpebra: relato de caso

ABSTRACT Ocular adnexal involvement in CD30+ lymphoproliferative disorders is rare. We report the case of a 73-year-old woman with a relapsing primary cutaneous anaplastic large cell lymphoma on her eyelid. A systemic extension study excluded extracutaneous involvement. Systemic chemotherapy resulted in an optimal response, with complete regression of the cutaneous lesions. There has been no recurrence during the 2 years of follow-up.

RESUMO O acometimento ocular adicional nos distúrbios linfoproliferativos CD30+ é raro. Relatamos o caso de uma mulher de 73 anos com linfoma de grandes células anaplásicas primárias recidivantes em sua pálpebra. A avaliação sistêmica excluiu envolvimento extracutâneo. A quimioterapia sistémica resultou em uma resposta ótima, com regressão completa das lesões cutáneas. Não houve recidiva durante 2 anos de acompanhamento.

Atypical presentation of fibroepithelial polyp: a report of two cases / Apresentação atípica de pólipo fibroepitelial: um relato de dois casos

ABSTRACT Fibroepithelial polyps are benign non-epithelial tumors arising from mesodermal tissue and are commonly found on the skin. They can develop on the eyelid and surrounding area and rarely appear at other sites. While most cutaneous cases are diagnosed incidentally, the lesions may be symptomatic based on their location. The etiology of fibroepithelial polyps is not fully understood but may involve trauma, chronic irritation, allergic factors, and developmental or congenital causes. Although fibroepithelial polyps are benign lesions, they can be malignant in extremely rare cases. Herein we discuss 2 cases of fibroepithelial polyp with an atypical presentation and their treatment.

RESUMO Pólipos fibroepiteliais são tumores benignos não-epiteliais que surgem do tecido mesodérmico e são comumente encontrados na pele. Eles podem se desenvolver na pálpebra e na área adjacente, e raramente aparecem em outros locais. Embora a maioria dos casos cutâneos seja diagnosticada incidentalmente, as lesões podem ser sintomáticas com base em sua localização. A etiologia dos pólipos fibroepiteliais não é completamente compreendida, mas pode envolver trauma, irritação crônica, fatores alérgicos e causas de desenvolvimento ou congênitas. Apesar dos pólipos fibroepiteliais serem lesões benignas, podem ser malignos em casos extremamente raros. Aqui discutimos 2 casos de pólipo fibroepitelial com uma apresentação atípica e seu tratamento.

Lentigo maligno na face: um desafio na conduta / Lentigo maligna on the face: a challenging conduct

Resumo O lentigo maligno é um melanoma in situ, de crescimento radial e lento, que acomete áreas fotoexpostas principalmente em idosos. Quando acomete a pálpebra, devido à proximidade a um órgão nobre, a conduta é controversa, porém a cirurgia é o método mais usado, com margens que variam de acordo com a referência utilizada. Terapias conservadoras são descritas, como o imiquimode 5% e a radioterapia. O presente relato tem como objetivo demonstrar a escassez de estudos sobre a margem cirúrgica e citar opções de tratamentos não cirúrgicos para o lentigo maligno da face.

Abstract Lentigo maligna is a melanoma in situ, of slow radial growth, which affects sun-exposed areas, especially in the elderly. When it affects the eyelid, due to the proximity to a noble organ, the conduct is controversial, but surgery is the method most commonly used, with with margins varying according to the reference used. Conservative treatments are described, such as imiquimod 5% and radiotherapy. This report aims to demonstrate the lack of studies on the surgical margin, and to name nonsurgical treatment options for lentigo maligna of the face.

Diagnosis of aggressive subtypes of eyelid basal cell carcinoma by 2-mm punch biopsy: prospective and comparative study / Diagnóstico dos subtipos agressivos de carcinoma basocelular palpebral pela biópsia por trépano de 2mm: estudo prospectivo e comparativo

ABSTRACT Objective : to compare the accuracy of preoperative 2-mm punch biopsy at one site and at two sites in the diagnosis of aggressive subtypes of eyelid basal cell carcinoma (BCC). Methods : we randomly assigned patients to Group 1 (biopsy at one site) and Group 2 (biopsy at two sites). We compared the biopsy results to the gold standard (pathology of the surgical specimen). We calculated the sensitivity, specificity, positive predictive value, negative predictive value, accuracy and Kappa coefficient to determine the level of agreement in both groups. Results : we analyzed 105 lesions (Group 1: n = 44; Group 2: n = 61). The agreement was 54.5% in Group 1 and 73.8% in Group 2 (p = 0.041). There was no significant difference between the groups regarding the distribution of quantitative and qualitative variables (gender, age, disease duration, tumor larger diameter, area and commitment of margins). Biopsy at two sites was two times more likely to agree with the gold standard than the biopsy of a single site. Conclusions : the accuracy and the performance indicators were better for 2-mm punch biopsy in two sites than in one site for the diagnosis of aggressive subtypes of eyelid BCC.

RESUMO Objetivo: comparar a acurácia da biópsia pré-operatória por trépano de 2mm em um sítio e em dois sítios no diagnóstico dos subtipos agressivos de carcinoma basocelular (CBC) palpebral. Métodos: os pacientes foram distribuídos aleatoriamente em Grupo 1 (biópsia em um sítio) e Grupo 2 (biópsia em dois sítios). Os resultados das biópsias foram comparados com o padrão-ouro (exame anatomopatológico da peça cirúrgica). A sensibilidade, especificidade, valor preditivo positivo, valor preditivo negativo, precisão e coeficiente Kappa foram calculados para determinar o nível de concordância nos dois grupos. Resultados: foram analisadas 105 lesões (Grupo 1: n = 44; Grupo 2: n = 61). A concordância foi de 54,5% no Grupo 1 e 73,8% no Grupo 2 (p-valor = 0,041). Não houve diferença significativa entre os grupos quanto à distribuição das variáveis quantitativas e qualitativas (sexo, idade, duração da doença, maior diâmetro do tumor, área e comprometimento de margens). A biópsia em dois sítios mostrou duas vezes mais chance de concordar com o padrão-ouro do que a biópsia de um sítio. Conclusões: a acurácia e os indicadores de desempenho foram melhores para a biópsia por trépano de 2 mm em dois sítios do que em um sítio para o diagnóstico dos subtipos agressivos de CBC palpebral.

Aplicación de técnicas reconstructivas en el manejo de los pacientes con tumores malignos del párpado inferior / Use of reconstructive techniques in management of patients with lower eyelid malignant tumors

Objetivos: caracterizar la aplicación de las técnicas reconstructivas utilizadas en el manejo de los pacientes con tumores malignos de párpado inferior según edad, sexo, color de la piel, tipo de neoplasia, localización de la neoplasia, ojo afectado, clasificación quirúrgica y complicaciones posquirúrgicas. Métodos: estudio descriptivo y longitudinal en el Instituto de Oncología y Radiobiología de La Habana, entre septiembre de 2013 y agosto de 2014, de pacientes que presentaron tumores malignos del párpado inferior. Se constituyó una muestra de 38 pacientes. Resultados: el sexo más afectado fue el masculino (73,6 por ciento); las edades más frecuente de presentación fueron entre 60 a 69 años (42,3 por ciento), en pacientes de piel blanca (86,8 por ciento). El carcinoma basocelular fue el de mayor incidencia histológica (68,5 por ciento); el ojo derecho fue el más vulnerado (65,8 por cietno), en la localización del tercio medio del párpado inferior; el mayor grupo se clasificó como T2N0M0 (39,5 por ciento). La complicación aguda más frecuente fue el hematoma del sitio operatorio (10,5 por ciento) y dentro de las tardías el lagoftalmo (7,8 por ciento). La técnica quirúrgica más empleada fue el colgajo rotado de mejilla (34,2 por ciento). Conclusiones: los resultados logrados en la reconstrucción integral del párpado inferior fueron satisfactorios en todos los casos, estructural y funcionalmente, con una mejoría de la apariencia física y de la calidad de vida de los pacientes(AU)

Objectives: to characterize the use of reconstructive techniques to manage patients with malignant lower eyelid tumor as per age, sex, race, type and location of neoplasia, affected eye, surgical classification and postsurgery complications. Methods: descriptive and longitudinal study carried out in the National Oncology and Radiobiology Institute in Havana city from September 2013 through August 2014. The study sample was made up of 38 patients who suffered malignant lower eyelid tumors. Results: males (73,6 percent); 60 to 69 years old patients (42,3 percent) and Caucasians (86,8 percent) were the most affected people. Basal cell carcinoma showed the most histological incidence (68,5 percent); the right eye was the most vulnerable (65,8 percent) and tumor location in the middle third of the eyelid (31,5 percent) prevailed. Most part of the patients was included in the T2 N0M0 staging group; (39,5 percent). The main severe complication was hematoma in the surgical site (10,5 percent) whereas lagophtalmo (7,8 percent) was predominant in the postoperative complications. Rotate cheek flap technique was the most used for the reconstruction of the eyelid (34,2 percent). Conclusions: the results of the comprehensive reconstruction of the lower eyelid were operationally and structurally satisfactory in all cases, with better physical appearance and higher quality of life in all patients(AU)

Primary cutaneous adenoid cystic carcinoma of the eyelid and literature review / Carcinoma adenóide cístico cutâneo primário de pálpebra e revisão da literatura

ABSTRACTPrimary cutaneous adenoid cystic carcinoma (PCACC) is a rare malignant epithelial tumor most commonly observed in the scalp and skin of the chest and originating from the palpebral portion of the lacrimal gland in the orbit. Here we describe the diagnosis and treatment of a rare case of PCACC in an eye of a 52-year-old male. The patient presented with a mass lesion of the right lower eyelid. During incisional biopsy, lack of encapsulation and a secretion pattern different to that of chalazion was observed, which differentiated the lesion from chalazion. Pathological analysis revealed the diagnosis of PCACC. This case highlights the importance of careful inspection for macroscopic differentiation of PCACC from chalazion after initial surgery and pathological evaluation of all surgically removed mass lesions for accurate diagnosis and treatment.

RESUMOO carcinoma adenóide cístico cutâneo primário (PCACC) é um tumor maligno epitelial raro, mais comumente observado no couro cabeludo e na pele do peito sendo originário da porção palpebral da glândula lacrimal na órbita. Apresentamos o diagnóstico e tratamento de um caso raro de carcinoma adenóide cístico cutâneo primário do olho em um paciente do sexo masculino de 52 anos de idade, com uma lesão maciça da pálpebra inferior direita. A observação da falta de encapsulamento e um padrão de secreção diferente do calázio durante biópsia incisional permitiu a diferenciação da lesão de um calázio. A avaliação dos resultados do exame patológico resultou no diagnóstico de carcinoma adenóide cístico cutâneo primário. A análise do caso indica a importância de uma inspeção cuidadosa para a diferenciação macroscópica da carcinoma adenóide cístico cutâneo primário do calázio após a cirurgia inicial e avaliação patológica de todas as lesões de massa removidas cirurgicamente para o diagnóstico e tratamento corretos.

Modified Tripier flap in reconstruction of the lower eyelid

We describe the use of modified Tripier flap for reconstruction of a surgical defect in the lower eyelid region, after excision of nodular basal cell carcinoma.

Acurácia do exame clínico no diagnóstico de lesões palpebrais / Accuracy of clinical examination in the diagnosis of eyelid lesions

Objetivo: Analisar a acurácia do exame clínico no diagnóstico de lesões palpebrais. Métodos: A partir da observação de trinta e cinco fotos de tumores palpebrais benignos e malignos que foram apresentadas a médicos oftalmologistas, para cada foto foram feitas 3 perguntas: 1) lesão maligna ou não? 2) se considerado maligno, o provável tipo histológico; e 3) tumor agressivo ou não? Os médicos foram agrupados em 9 grupos, de acordo com a formação profissional (tempo de formação e especialização ou não em Oculoplástica). As respostas foram comparadas com o resultado do exame histopatológico da peça retirada cirurgicamente. Resultados: No total, cento e seis médicos oftalmologistas participaram do estudo. A experiência do profissional influenciou no diagnóstico de malignidade do tumor, já que o grupo 1 (residentes de primeiro ano) apresentou a menor acurácia (64,5%), com menor concordância estimada (Kappa = 0,13), e o grupo 5 (formados há 5 anos e especializados em Oculoplástica) a maior acurácia (77,3%), com melhor concordância (Kappa = 0,45), além de apresentar as melhores medidas para os demais itens avaliados. Para diagnóstico do tipo histológico, a acurácia foi menor no grupo 1 que obteve o pior desempenho, com 51,1% de acurácia, enquanto o melhor foi o grupo 6 (formados há mais de 5 anos e especializados em Oculoplástica, 77,2%). Já para o critério de agressividade do tumor os resultados foram mais próximos entre as diferentes categorias. Os oftalmologistas formados há mais tempo e sem especialização em Oculoplástica também demonstraram baixa acurácia diagnóstica no diagnóstico de malignidade e na determinação do tipo histológico do tumor. Conclusão: A baixa acurácia no diagnóstico clínico de tumores palpebrais nos grupos acima referidos reforça a necessidade de melhorar o conhecimento em oncologia palpebral nesses grupos. .

Objective: To analyze the accuracy of the clinical examination in the diagnosis of eyelid lesions. Methods: From the observation of thirtyfive photos of benign and malignant eyelid tumors were presented to ophthalmologists, for each picture, it was asked 3 questions: 1) the lesion is malignant or not; 2) if considered malignant, the probably histological type; and 3) the tumor is aggressive or not. The phisicians were divided into 9 groups, according to academic degree (time since graduation and Oculoplastics specialty or not). Answers were compared with the results of the histopathologic study of the surgically resected tumor. Results: In total, one hundred and six ophthalmologists were interviewed. The professional experience influenced the diagnosis of malignancy of the tumor, as the Group 1 (first year residents) had the lowest accuracy (64.5%), with lower estimated agreement (kappa = 0.13), and Group 5 (graduated 5 years ago and with expertise in Oculoplastics) the highest accuracy (77.3%), with better agreement (Kappa = 0.45), and presented the best parameters for other analyzed items. For the histological type diagnosis, accuracy was lower: group 1 had the worst performance, with 51.1% accuracy, while the best was for group 6 (graduated over 5 years and with expertise in Oculoplastics, 77.2% ). As for the criterion of tumor aggressiveness, the results were closer among the different categories. Ophthalmologists trained longer and without expertise in Oculoplastics also showed a low diagnostic accuracy for malignancy and to determine the histological type of tumor. Conclusions: The low accuracy of clinical diagnosis of eyelid tumors in the groups above reinforces the need to improve ophthalmic oncology knowledge in these groups. .

Schwannoma em pálpebra superior esquerda em criança de 10 anos / Schwannoma of the left superior eyelid in a 10-year-old child

Schwannoma é um tumor neurogênico benigno raro, originário das células de Schwann da bainha de mielina dos nervos periféricos. Sua localização nos tecidos oculares não é comum, sendo a órbita o local afetado com maior frequência e o acometimento das pálpebras é muito raro. Há poucos relatos descritos na literatura sobre Schwannoma palpebral, apenas dois em crianças. Este é, em nosso conhecimento, o primeiro caso relatado no Brasil.

Schwannoma is a rare benign neurogenic tumor. It arises from Schwann cells located at the myelin sheath of peripheral nerves. Its incidence is frequently associated with the orbit. Ocular tissues in general and eyelids in particular are rarely affected. Very few reports can be found in the literature describing eyelid schwannomas. Amongst these, we have found only two describing it affecting children. To our knowledge, this is the first case report about eyelid schwanomma in Brazil - and it involves a child.

Cuerno cutáneo y carcinoma sebáceo: diagnóstico diferencial a propósito de un caso / Cutaneous horn and sebaceous carcinoma: differential diagnosis of a case report

El cuerno cutáneo es un concepto semiológico. Se define como una lesión tumoral hiperqueratósica de aspecto cónico y tamaño variable, que puede tener como base una lesión de origen benigno, premaligno o maligno. El tratamiento consiste en la resección completa de la lesión, seguido de un estudio histopatológico para precisar el diagnóstico. El carcinoma sebáceo, neoplasia maligna derivada del epitelioanexial de las glándulas sebáceas, se ha descrito como una etiología poco frecuente de cuerno cutáneo. Su diagnóstico es difícil, ya que carece de elementos clínicos característicos y su histología puede ser similar al carcinoma espinocelular o basocelular, pero importante ya que constituye una neoplasia agresiva, con riesgo de recurrencia local y metástasis. A continuación, presentamos el caso de un hombre de 68 años con diagnóstico clínico de cuerno cutáneo palpebral y diagnóstico histopatológico de carcinoma sebáceo.

The cutaneous horn is a semiological concept. It is defined as an hyperkeratotic tumor of conical appearance and variable size, which may be based on benign, premalignant or malignant lesion. The treatment is the complete resection followed by an histopathology study to clarify the diagnosis. Sebaceous carcinoma, malignant neoplasm derived from adnexal epithelium of sebaceous glands, has been described as a rare etiology of cutaneous horn. Diagnosis is difficult because it doesn’t have characteristic clinical features and histology may be similar to squamous or basal cell carcinoma, but it is important because is an aggressive neoplasm with risk of local recurrence and metastasis. We present a case of a 68-year-old man, with a clinical diagnosis of eyelid cutaneous horn and histopathological diagnosis of sebaceous carcinoma.

A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast

We report a case of Muir-Torre syndrome (MTS) with a very rare combination of cancers, involving bilateral eyelid cancers and breast cancer. A 71-year-old female with a history of breast cancer from 18 years prior presented with bilateral eyelid tumors. One of her siblings had lung cancer, and another had pancreatic cancer. She underwent excisional biopsy of the eyelid tumors and histopathology revealed sebaceous carcinoma of the right eyelid and basal cell carcinoma of the left. She was diagnosed with MTS: a skin cancer associated with visceral malignancy. Immunohistochemical tests for mutS homolog 2 showed a lack of expression in both eyelid carcinomas.

Eyelid masses: a 10-year survey from a tertiary eye hospital in Tehran

The purpose of this study was to evaluate the demographics and clinical features of eyelid masses in a tertiary eye hospital over a 10-year period. A retrospective chart review was performed for patients admitted with eyelid tumors from 2000 to 2010. Data were collected and analyzed on the demographic features, location of the tumor, types of treatment, and pathologic findings. A total number of 182 patients were evaluated of which, 82 cases were benign and 100 cases were malignant neoplasms. The most common benign tumors included melanocytic nevi [35%], papilloma [19.5%], and cysts [11%]. The most frequent malignant tumors included basal cell carcinoma [BCC] [83%], squamous cell carcinoma [8%] and sebaceous gland carcinoma [6%]. The most common site for malignancy was the lower lid followed by the upper lid. BCC recurred in 16 cases that were most frequent in the lower lid. Melanocytic nevus, papilloma and cysts are the most common benign lesions and BCC is the most common malignant lesion in the eyelids. Recurrence is a feature of BCC especially in the lower lid

Colgajos en la reconstrucción facial en dos pacientes con carcinoma basocelular / Flaps in the facial reconstruction in two patients with basal cell carcinoma

En la cara se encuentran estructuras con una función perfectamente delimitada, además de un componente estético muy importante. Intentamos mostrar la utilidad de colgajos de piel en la reconstrucción facial en dos pacientes con carcinoma basocelular. Se realizó un estudio descriptivo retrospectivo de dos casos en que se practicó resección de lesiones: nasal, en mejilla. En pacientes que acudieron al Centro Clínico Valentina Canabal, entre enero y diciembre 2009. Los dos pacientes tenían diagnóstico de carcinoma basocelular, los procedimientos utilizados fueron: colgajo pediculado y Z plastia, la evolución de los casos fue satisfactoria, sin secuelas funcionales y resultados estéticos excelentes, el tiempo quirúrgico promedio fue de 80 min. y la hospitalización duró un máximo de dos días. En nuestra experiencia se demuestra la gran utilidad de los colgajos en las reconstrucciones faciales con resultados tanto estéticos como funcionales favorables.

In the face the structures are well defined function, and have very important aesthetic component. We try to show the usefulness of skin flaps in facial reconstruction in two patients with diagnostic of basal cell carcinoma. We conducted a retrospective study of two cases in which resection of lesions nasal, and in the cheek. In patients who attended in the Center Clinical Valentina Canabal, between January and December 2009. Both patients had a diagnosis of skin basal cell carcinoma, the procedures used were pedicles flap and Z-plastic, the patient outcome was satisfactory, without complications, functional disability and excellent cosmetic results, the average surgical time was 80 minutes hospitalization lasted a maximum of two days. In our experience we demonstrates the usefulness of the flaps in the facial reconstruction, with favorable results and aesthetic and functional satisfactory to the patients.

Melanose da margem palpebral com suspeita de malignidade: relato de caso / Melanosis in eyelid margin with malignancy suspect: case report

Apresenta-se relato de caso de paciente parda, com 47 anos de idade, havendo lesão pigmentada na margem palpebral inferior do olho direito, de aspecto irregular e heterogêneo, suspeitando-se clinicamente de lesão maligna. A paciente foi tratada com base no resultado da citologia de impressão e diagnosticada pelo exame histológico. Demonstra-se a importância da citologia para o planejamento da ressecção de lesões suspeitas como um método seguro e efetivo para assim se evitar cirurgias em áreas extensas da superfície ocular e de anexos.

A case of a patient with an irregular pigmented lesion of the lower eyelid margin simulating malignant tumor, which was treated based on the results of impression cytology and diagnosed by histopathological study is presented. The importance of cytological technique is emphasized as an effective and safe method that avoids unnecessary and extensive procedures.

Schwannoma of the eyelid: Apropos of two cases.

Schwannoma, also referred to as neurilemmoma, is a benign tumor of peripheral nerve arising from Schwann cells that form the neural sheath. Schwannoma of ophthalmic interest is rare although it has been reported in relation with the orbit, and less frequently with the uveal tract and conjunctiva. Isolated eyelid schwannoma is extremely uncommon. Up until now, only eight cases have been reported in literature. Herein, we report two cases of eyelid schwannoma.

Nódulos calcificados subepidérmicos palpebrales / Subepidermal calcified nodules palpebral

La calcinosis cutis comprende cuatro formas de presentación: calcinosis cutis metastásica, calcinosis distrófica, calcinosis idiopática y nódulos calcificados subepidérmicos. La calcinosis cutis metastásica se desarrolla como resultado de hipercalcemia o hiperfosfatemia. En la calcinosis cutis distrófica, el calcio se deposita sobre un tejido previamente dañado. La calcinosis cutis idiopática es similar a la calcificación distrófica, pero se presenta sin evidencia de enfermedad subyacente. Los nódulos calcificados subepidérmicos, también conocidos como cálculos cutáneos se observan como lesiones pequeñas, elevadas y únicas. Se ven en niños o adultos jóvenes. El aspecto puede ser verrugoso o en casos tiene apariencia suave. La localización más común es en la cara. Se presentan cinco casos con diagnóstico de nódulos calcificados subepidérmicos, localizados en el párpado, diagnosticados en la Sección de Patología Ocular del Instituto Anatomopatológico "Dr. J. A. O’Daly"

Cutis calcinosis has four clinical presentations: metastatic calcinosis cutis, dystrophic calcinosis, idiopathic calcinosis and sub epidermal calcified nodules. Metastatic cutis calcinosis occurs as a result of hypercalcaemia or hyperphosphatemia. In dystrophic calcinosis cutis, calcium is deposited over a previously damaged tissue. Similar to dystrophic calcinosis, idiopathic calcinosis cutis is presented without any subjacent illness. Sub epidermal calcified nodules, also known as a cutaneous calculus are tiny, unique and elevated lesions. It is appear in children or young adults. The clinical aspect may be since soft lesions to verrugous appearance. The most common site to be seen is on the face. We present five eyelid sub epidermal calcified nodules diagnosed in Ocular Pathology Section at The Instituto Anatomopatologico "Dr. Jose A. O’Daly"

Primary mucinous carcinoma of eyelid: a rare clinical entity.

Primary cutaneous mucinous carcinoma of the eyelid, a rare pathologic entity, is an adenocarcinoma of the eccrine glands. Though it has low metastatic potential, it does have a significant recurrence rate. We present the occurrence, clinical and histological features, and management of this tumor in a 62-year-old male who presented with a recurrent, firm, nodular left lower lid lesion. He underwent excision with a 5 mm margin and the defect was repaired with a Mustarde's cheek rotation flap. A full oncological screening, including whole-body Positron Emission Tomography scan, excluded the presence of primary mucinous carcinoma elsewhere and any metastatic spread. This case underscores the importance of considering this tumor in recalcitrant eyelid lesions and highlights the pathology of this tumor.

Fibro-histiocitoma maligno da pálpebra: relato de caso / Malignant fibrous histiocytoma of the eyelid: case report

Os fibro-histiocitomas representam 1 por cento das massas orbitárias e podem ser histologicamente classificados em benignos, localmente agressivos e malignos - os últimos representando aproximadamente 11 por cento do total. Nesse estudo, os autores descrevem um caso raro de fibro-histiocitoma maligno de pálpebra, ressaltando as características clínicas e histopatológicas desta neoplasia.

Fibrous histiocytomas represent 1 percent of all orbital masses and may be classified into benign, locally aggressive and malignant - these representing nearly 11 percent of the total. In this study, the authors describe an unusual case of malignant fibrous histiocytoma of the eyelid, discussing clinical and histological features of this neoplasm.