Inflammatory Myofibroblastic Tumor on Intercostal Nerve Presenting as Paraneoplastic Pemphigus with Fatal Pulmonary Involvement

Inflammatory myofibroblastic tumors (IMTs) are benign neoplasms that can occur at different anatomic sites with nonspecific clinical symptoms. A 48-yr-old woman presented with a 2-month history of a relapsed oral ulcer, progressive dyspnea, and a thoracic pain induced by breathing. A tumorous mass was noticed in the right costodiaphragmatic recess on chest computed tomography and magnetic resonance imaging, and the patient underwent a right costotransversectomy with excision of the tumor, which originated from the 12th intercostal nerve. Histology and immunohistochemistry showed that the tumor was an IMT of the intercostal nerve. The patient's postoperative course was not favorable; dyspnea persisted after surgery, and a progressive pulmonary compromise developed. The cause of the respiratory failure was found to be bronchiolitis obliterans, which in this case proved to be a fatal complication of paraneoplastic pemphigus associated with an IMT. This case of IMT of the spinal nerve in the paravertebral region is unique in terms of its location and presentation in combination with paraneoplastic pemphigus, which is rare. A brief review of the heterogeneous theories concerning the pathogenesis, clinicopathological features, and differential diagnosis of this disease entity is presented.

Cauda equina paraganglioma presenting with intracranial hypertension: case report and review of the literature.

An unusual case of intradural paragangliomas in the cauda equina region in a 29-year-old male is presented. The patient presented with signs and symptoms of raised intracranial pressure. The symptoms resolved after tumor resection.

Sciatica due to malignant nerve sheath tumour of sciatic nerve in the thigh.

Malignant peripheral nerve sheath tumour (MPNST) is a rare malignant neoplasm arising from the supportive non-neural component of the peripheral nerves. An unusual case of pain and weakness of the foot and calf muscles due to a giant MPNST of the sciatic nerve in the posterior compartment of the thigh is presented. The patient was already investigated as a case of sciatica due to a lumbar disc disease with a negative magnetic resonance imaging and then unsuccessfully operated elsewhere twice, with a misdiagnosis of tarsal tunnel syndrome. Neurosurgical referral prompted a diagnostic magnetic resonance study of the thigh, revealing the lesion, which was completely excised microsurgically with total relief in the pain and partial improvement in the weakness and sensations in the sole of the foot.

Tumor autonomico gastrointestinal asociado a enfermedad de von Recklinghausen / Gastrointestinal autonomic tumor associated with von Recklinghausen's disease

El tumor autonómico gastrointestinal es un tipo raro de tumor estromal gasrointestinal que parece originarse del plexo autónomo mioentérico. Ocasionalmente estos tumores han estado asociados a enfermedad de von Recklinghausen (EVR). Presentamos el caso de una mujer de 63 años con EVR con dos tumores ileales que evidenciaron las características de los tumores autonómicos gastrointestinales y una revisión de la literatura sobre esta peculiar combinación.

Paraganglioma of the cauda equina region--a report of two cases with review of literature.

Among all extra-adrenal locations, paragangliomas are least commonly found within the spinal canal. so far over 60 cases of paragrangliomas in the Cauda equinal region have been reported. In this report we describe the salient clinical and histopathological features of paraganglioma of the cauda equinal region in two patients.

Meningeoma invasivo de cauda equina associado a hidrocefalia e a edema de papila: relato de caso / Hydrocephalus and intracranial hypertension due to invasive meningeoma of the cauda equina: case report

Os autores apresentam um caso de meningeoma invasivo da cauda equina associada a hidrocefalia e a hipertensäo intracraniana com edema de papila. Como trata-se de associaçäo pouco frequente, discutimos a fisiopatologia baseando-nos em uma revisçäo das teorias propostas na literatura disponível

Radiculopatia neoplásica lombossacral / Neoplasic lumbosacral radiculopathy

Comentário crítico da rotina radiodiagnóstica nas radiculopatias lombossacrais no que concerne ao uso da tomografia computadorizada (CT). Säo relatadas as observaçöes clínicas de três pacientes nos quais neoplasias acometeram uma única raiz lombossacral, simulando uma hérnia de disco lombar do ponto de vista clínico, com ênfase nos aspectos neurorradiológicos. Recomenda-se o estudo, sistemático do sacro e da zona do cone medular em todo caso de radiculopatia lombossacral

Macrodactylism Associated with Neurofibroma of the Median Nerve: A Case Report

A case of macrodactyly associated with neurofiborma of the median nerve, a congenital anomaly of the hand, affecting only one(left middle) finger is reported with a review of the literature. Macrodactyly which is also termed local gigantism, megalodactylism, megalodactylia, or macrodactylism in other literature, is a rare congenital malformation characterized by overgrowth of one or more fingers of hand. Macrodactyly associated with neurofibroma of the median nerve is especially rare. For this reason the following case is presented together with a review of the literature.