Report of rare palatal expression of Nevus of Ota with amendment of Tanino's classification.

Nevus of Ota, a benign melanocytic pigmentary disorder with rare malignant transformation potential, affects 0.014-0.034% of the Asian and Black population and has a strong predilection for females. It occurs in the area innervated by the first and second division of the trigeminal nerve. Oral manifestation is rarely noted with only 14 cases reported till date. This report documents a case of Nevus of Ota with the infrequently noted oral involvement, in an Indian lady. Since oral manifestation is not acknowledged in Tanino's classification, the authors propose a modification to the same.

Nevus of Ota: clinical-ophthalmological findings / Nevo de Ota: achados clínicos e oftalmológicos

OBJECTIVE: To analyze the clinical and ophthalmological findings of patients with nevus of Ota. METHODS: Retrospective analysis of patients' charts with nevus of Ota. We registered the demographic data, location of the nevus and date of appearance, family history of similar spots, biomicroscopic, gonioscopic, tonometric, ophthalmoscopic and perimetric findings. RESULTS: We included 14 patients, six (43.0 percent) men and eight (57.0 percent) women, with a mean age of 21.7±17.5 years. Ten (71 percent) were mulatto, three (21.4 percent) white and one (7.1 percent) black. Twelve (85.7 percent) patients presented the spots at birth and two in puberty. Nine patients presented conjunctival and episcleral pigmentation in the right eye and five in the left eye. According to Tanino's classification, five (35.7 percent) nevi were class 1, eight (57.1 percent) class 2 and one (7.1 percent) class 3. Heterochromia iridis was found in eight (57.1 percent) patients. Anisocoria was present in three (21.4 percent) patients. Five (35.7 percent) patients presented a suspected glaucomatous cup disc ratio (≥0.7); six (42.9 percent) presented a cup disc ratio ≤ 0.5 and three (21.4 percent), no cup disc. We found two curious and remarkable findings: a nevus of Ota on the palate of one patient and other on the optic disc associated with a pigmentary mottling of the fundus in another patient. The pigmentary mottling of the fundus was also seen in four more eyes. CONCLUSIONS: The nevus of Ota was frequently present at birth, in mulattos, and classified as Tanino's class 1 and 2. Heterochromia iridis was a common finding. Anisocoria was present in a small percentage of eyes. No patient developed glaucoma or malignancy.

OBJETIVO: Analisar os achados clínico-oftalmológicos de portadores de nevo de Ota. MÉTODOS: Análise retrospectiva dos prontuários de pacientes com nevo de Ota. Foram registrados dados demográficos, localização do nevo e época do seu aparecimento, história familiar de manchas similares, olho acometido, achados ectoscópicos (classificação de Tanino), biomicroscópicos, fundoscópicos e campimétricos. RESULTADOS: Foram incluídos 14 pacientes, seis (47,0 por cento) homens e oito (53,0 por cento) mulheres com média de idade de 21,7±17,5 anos. Dez (71 por cento) pacientes eram feodérmicos, três (21,4 por cento) leucodérmicos e um (7,1 por cento) melanodérmico. Doze (85,7 por cento) pacientes apresentaram manchas ao nascimento e dois relataram seu surgimento após o nascimento. Três pacientes relataram manchas compatíveis com nevo de Ota em consanguíneos. A melanose conjuntivo-episcleral foi reconhecida no olho direito em cinco pacientes e em nove no olho esquerdo. Pela classificação de Tanino, cinco (35,7 por cento) dos nevos eram da classe 1, oito (57,1 por cento) da classe 2 e um (7,1 por cento) da classe 3. Presença de heterocromia da íris em oito (57,2 por cento) pacientes. Anisocoria ocorreu em três pacientes. Disco óptico suspeito de glaucoma (relação escavação/disco ≥ 0,7) foi observado em cinco pacientes (35.7 por cento); seis apresentaram escavação fisiológica e três não apresentavam escavação. Dois achados curiosos e raros: um nevo de Ota no palato de um paciente e outro no disco óptico de outro paciente associado com pigmentação difusa no polo posterior retiniano. Essa pigmentação foi também vista em mais quatro olhos. CONCLUSÃO: O nevo de Ota foi mais comumente presente ao nascimento, em feodérmicos e nas classes 1 e 2 de Tanino. Heterocromia iriana achado comum. Anisocoria foi diagnosticada num percentual pequeno de pacientes. Nenhum paciente desenvolveu glaucoma nem tumor maligno.

Nevus of Ota: a series of 15 cases.

BACKGROUND: The nevus of Ota is a dermal nevus characterized by bluish pigmentation in the distribution of the first and the second division of the trigeminal nerve. AIM: Our aim was to study the cutaneous and extracutaneous manifestations of the nevus of Ota. METHODS: A total of 15 cases were included in our study. A detailed history, clinical examination along with direct ophthalmoscopy and otoscopy were done for all the cases. RESULTS: Most of the patients (60%) had lesions at birth and the majority (86.7 %) were females. Five (33.3%) patients belonged to Tanino class II. Combined dermal and ocular involvement was observed in 60% of the cases. CONCLUSION: Tanino class II was the most common type observed in our studies. A few rarer associations such as nevus of Ito and hemangioma were also noted in our patients.

Bilateral nevus of Ota

Nevus of Ota is a dermal melanocytosis seen in the distribution of ophthalmic, maxillary and mandibular divisions of the trigeminal nerve. Most of the cases reported are in females with a typical unilateral distribution. We describe a case of bilateral nevus of Ota in a male

Asociación de síndromes de Sturge-Weber-Dimitri y Klippel-Trénaunay con nevo de Ota bilateral: una variante de la facomatosis pigmentovascular / An association of Stuge-Weber-Dimitri and Klippel-Trenaunay syndromes with bilateral Ota's naevus: a variant of pigmentovascular phakomatosis

Presentamos un caso de asociación de los síndromes de Sturge-Weber-Dimitri y Klippel-Trénaunay con nevo de Ota bilateral. Además de destacar la infrecuencia de dicha asociación y encuadrarla dentro de las facomatosis pigmentovasculares, se pondera la ubicación nosológica de los nevus flammeus como malformación vascular y se hace una revisión de la clasificación de nevo de Ota

Nevo de Ota bilateral / Bilateral Nevus of Ota

Se estudia un paciente de sexo femenino, de 29 años de edad, con nevo de Ota bilateral, sin complicaciones al examen oftalmológico y leve hipoacusia de conducción derecha. Radiografía, tomografía y electroencefalograma normal. Se pasa revista a la clasificación y se lo considera de tipo difuso con pigmento en dermis papilar y reticular. En el cuadro N§1 se puntualizan las diferencias clínicas con el melasma, nevo zigomático y el nevo de Ota-"like". Se enfatiza en la necesidad de educar al paciente para su examen periódico y controlar la aparición de complicaciones, recordando que puede sufrir una transformación maligna, principalmente en piel, coroides, iris, órbita y cerebro