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New Egyptian Journal of Medicine [The]. 2009; 41 (1): 26-34
en Inglés | IMEMR | ID: emr-113095

RESUMEN

In the present study, lactating infants' rat were given a dose of Carbamazepine [tegretol] [10mg/kg]. Mothers rat were divided into three groups: the first control group, the second was supplied with the drug while the third was provided with the drug and a mixture of Nigella and honey. Histological investigations showed serious damages of liver, kidney, testis, spleen, ovary of infants of mothers treated with the drug. For liver, it could be recognized the disordered of structural architecture and inter- and intracellular fatty filtration. Also a reduction in the cortex size of the kidney with damaging of all its components, and appearance of oedema and vacuoles in the lymphatic tissues of spleen were recorded. On the other hand infants of treated mothers with the drug and the mixture showed a great improvement in histological structure of their organs with nearly normal structure and a decreasing in the critical effect of the drug


Asunto(s)
Femenino , Animales de Laboratorio , Ratas , Lactancia , Animales Lactantes , Estructuras Animales/patología , Histología , Sustancias Protectoras , Nigella sativa/estadística & datos numéricos , Miel/estadística & datos numéricos , Resultado del Tratamiento
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