Helicobacter pylori in nasal polyposis

Nasal polyposis is an inflammatory condition of unknown etiology. Recently concern regarding GER or Helicobacter pylori as a possible pathologic cause of nasal polyps has been increasing. The present study was planned to investigate the presence of Helicobacter Pylori in nasal polyps by PCR, rapid Urease test and serology. Case control study. ENT ward of Shiraz, Khalilli Hospital, Iran, April 2006 to March 2008. 37 patients with nasal polyps who had undergone nasal endoscopic sinus surgery and 38 control subjects who had undergone septoplasty and turbinectomy. Biopsy specimens of nasal polyps and inferior turbinates were assessed by PCR and Rapid Urease test. Blood sample of both study and control subjects were evaluated for anti H.pylori Ig G by ELISA. HP status was regarded as positive, if 2 tests were positive. Seropositivity was more common in the patients with nasal polyps [72.97%] than in the control patients [31.57%] [P-value= 0.000] RUT was positive in 9 [24.3%] of 37 patients with nasal polyps, but was not positive in control group [P-value= 0.001]. Only 3 of [8.1%] of 37 patients with nasal polyps were positive for both RUT and ELISA [P-value=0.115]. PCR was negative in all patients and controls. Polypoid tissue can be colonized by some other agents containing a urease enzyme other than Helicobacter Pylori. So, result of RUT can be false positive, and addition test may be performed. In the our study by using PCR, we were not able to confirm presence of Helicobacter pylori in the nasal polyps. However, further epidemiologic studies using different and specific diagnostic tests with control of documented GER is recommended

Biofilme em rinossinusite crônica com polipose nasossinusal: estudo piloto / Biofilm in chronic sinusitis with nasal polyps: pilot study

Apatogenia da rinossinusite crônica não está completamente estabelecida e existem algumas explicações para essa doença, como a osteíte, os superantígenos, a hipersensibilidade mediada por fungos e, mais recentemente, o biofilme. Não existem publicações na língua portuguesa sobre biofilmes na rinossinusite crônica. Objetivo: Reproduzir um método para evidenciar a presença de biofilmes em pacientes com rinossinusite crônica com polipose nasossinusal. Material e método: Amostras de bula etmoidal de nove pacientes com rinossinusite crônica com polipose nasossinusal sem resposta ao tratamento clínico submetidos à cirurgia foram analisadas com microscopia eletrônica de varredura para evidenciar o biofilme. Desenho do estudo: Estudo de coorte contemporânea com corte transversal. Resultados: Observamos o biofilme em 55,56 por cento (5/9) dos pacientes, através da visualização da estrutura tridimensional, de estruturas esféricas envolvidas por uma matriz amorfa e dos canais de água. Conclusão: Reproduzimos um método de visualização de biofilme bacteriano através da microscopia eletrônica de varredura e evidenciamos a sua presença nos pacientes com rinossinusite crônica com polipose nasossinusal.

Chronic rhinosinusitis pathogenesis is not completely established and there are some explanations for this disease, such as osteitis, superantigens, fungal-mediated hypersensitivity and, more recently, biofilms. There are no reports in Portuguese about biofilms in chronic rhinosinusitis. AIM: To reproduce a method for visualization of biofilms in patients with chronic rhinosinusitis and nasal polyps. Patients and methods: Samples of ethmoid bulla of nine patients with chronic rhinosinusitis with nasal polyps without response to clinical treatment who underwent surgery were analyzed with scanning electron microscopy to evidence bacterial biofilms. Study design: A contemporary cross-sectional cohort study Results: In 55.56 percent (5/9) of the patients we observed biofilms by seeing three-dimensional structures, spherical structures surrounded by an amorphous matrix and water-channels. Conclusion: We reproduced a method for visualization of bacterial biofilms by scanning electron microscopy and evidenced its presence in chronic rhinosinusitis with nasal polyps.

Severe epistaxis from rhinosporidiosis: a case report.

Rhinosporidiosis is quite rare in Thailand, but the actual incidence may be higher than the numbers reflect. This is thought to be due to misdiagnosis by physicians who are unfamiliar with this disease entity or physicians who found a case but did not describe its presence. The authors report a case in a 17 year old male with the lesion involving both nasal cavities, nasopharynx and left maxillary sinus presenting with severe epistaxis, which was treated by complete surgical removal with electric cauterization of its base. We warn physicians who face this problem to be aware of this disease entity.

Reporte del primer caso de rinosporidiosis en la provincia Ciego de Avila, Cuba / First case report of rhinosporidiosis at Ciego de Avila, Cuba

Se presenta el primer caso de rinosporidiosis diagnosticado en la provincia Ciego de Avila, Cuba, analizándose las características clinico epidemiológicas del caso. Paciente de 13 años de edad, de sexo masculino, proveniente de un área rural que presentaba localización nasal de las lesiones. Se revisa la literatura al respecto

Rinosporidiose nasal: relato de um caso / Nasal rhinosporidosis: a case report

Os autores relatam um caso de rinosporidiose nasal em uma criança negra de 12 anos, do sexo masculino, residente na regiäo norte do estado do Espírito Santo. Havia a formaçäo de um pólipo na narina direita com obstruçäo e sangramento. O diagnóstico clínico foi confirmado pelo exame micológico direto com clareamento e pela análise histopatológica, que acusaram a presença de esporângios sugestivos de Rhinosporidium seeberi

Rinosporidiosis en Costa Rica: revisión del tema e informe dell primer caso en nuestro país / Rhinosporidiosis in Costa Rica: review of the literature and report of the first Costa Rica care

Se hace una revisión de la rinosporidiosis. Además, se informa el primer caso en Costa Rica, diagnosticado en un paciente de 19 años de edad, vecino del cantón de Turrialba, a quien se le encontró un pólipo nasal con Rhinosporidium seeberi. Seis meses después del diagnóstico inicial, el paciente presentó recidiva