RESUMEN
ABSTRACT CONTEXT: Various skin manifestations have been reported in coronavirus disease. It may be difficult to determine the etiology of these lesions in view of the increased frequency of handwashing during the pandemic, along with occurrences of irritant contact dermatitis and allergic contact dermatitis due to disinfectant use; usage of herbal medicine and supplements to strengthen the immune system; and urticarial or maculopapular drug eruptions due to COVID-19 treatment. The variety of associated skin manifestations seen with COVID-19 makes it challenging to identify virus-specific skin manifestations. Petechiae, purpura, acrocyanosis and necrotic and non-necrotic purpura, which can be considered as manifestations of vascular involvement on the skin, have been reported. CASE REPORT: Here, we report a case of eruptive cherry angiomas, which was thought to have developed due to COVID-19, with a papulovesicular rash on distal extremities that progressed over time to reticular purpura. CONCLUSION: The case presented had a papulovesicular rash at the onset, which evolved to retiform purpura, and eruptive cherry angiomas were observed. It should be kept in mind that dermatological signs may vary in patients with COVID-19.
Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Púrpura/virología , Piel/virología , Enfermedades Cutáneas Virales/virología , Exantema/virología , COVID-19/complicaciones , COVID-19/virología , Hemangioma/virología , Piel/efectos de los fármacos , Piel/patología , Resultado del Tratamiento , Enfermedades Cutáneas Virales/diagnóstico , Enfermedades Cutáneas Virales/terapia , Prueba de COVID-19 , SARS-CoV-2 , COVID-19/tratamiento farmacológico , COVID-19/terapiaRESUMEN
Papular-purpuric gloves and socks syndrome is a rare, highly contagious dermatosis caused by parvovirus B19, which may result in the abrupt cessation of red blood cell production in patients with preexisting hematological diseases. It affects predominantly children and young adults and has an unusual presentation.
A síndrome "gloves and socks" pápulo-purpúrica é uma dermatose incomum, altamente contagiosa, causada pelo parvovírus B19, que pode provocar interrupção aguda da produção de glóbulos vermelhos em pacientes com doenças hematológicas preexistentes. Acomete, principalmente, crianças e jovens, e tem uma apresentaçao nao-usual.
Asunto(s)
Humanos , Femenino , Adulto , Púrpura/virología , Parvovirus B19 Humano , Enfermedades Cutáneas Virales/virología , Infecciones por Parvoviridae/complicaciones , Dermatosis del Pie/virología , Dermatosis de la Mano/virología , Púrpura/diagnóstico , SíndromeRESUMEN
Two atypical cases of parvovirus B19 infection occurred consecutively within a family. A 14 year-old patient presented an extended papular-purpuric "gloves and socks" syndrome and two weeks later his mother developed a predominantly unilateral purpuric rash in the limbs with severe malaise. Specific IgM antibodies in the boy and polymerase chain reaction (PCR) and serology in the mother, confirmed parvovirus B19 infection. We emphasize the variable presentation of B19 infection within a family. The importance ofetiologic studies in the presence of atypical exanthemas and the utility of PCR in the diagnosis ofB19 are undesrscored.
Asunto(s)
Adolescente , Adulto , Femenino , Humanos , Masculino , Eritema Infeccioso/diagnóstico , Exantema/diagnóstico , Dermatosis del Pie/virología , Dermatosis de la Mano/virología , Púrpura/diagnóstico , Eritema Infeccioso/virología , Exantema/virología , Familia , Dermatosis del Pie/patología , Dermatosis de la Mano/patología , /genética , Reacción en Cadena de la Polimerasa , Púrpura/virología , SíndromeRESUMEN
Papular-purpuric "gloves and socks" syndrome (PPGSS) is a novel, rare, self-limiting dermatosis caused by human parvovirus B19. It consists of pruritic edema and erythema of the hands and feet in a gloves-and-socks distribution, and it is associated with oral lesions and fever. We present a case of PPGSS in a 22-year-old Brazilian woman. Clinical and laboratory evaluation, including serological tests, PCR and gene sequencing, confirmed the presence of human parvovirus B19.
Asunto(s)
Adulto , Femenino , Humanos , Eritema Infeccioso/virología , Dermatosis del Pie/virología , Dermatosis de la Mano/virología , /aislamiento & purificación , Púrpura/virología , ADN Viral , Ensayo de Inmunoadsorción Enzimática , Eritema Infeccioso/diagnóstico , Dermatosis del Pie/diagnóstico , Dermatosis de la Mano/diagnóstico , Filogenia , Reacción en Cadena de la Polimerasa , /genética , Púrpura/diagnóstico , SíndromeRESUMEN
We present a case of papular-purpuric "gloves and socks" syndrome (PPGSS) in an adult male with acute parvovirus B19 infection. The patient displayed the classical features of fever, oral lesions, and purpura on hands and feet, but the purpuric lesions on the feet evolved to superficial skin necrosis, a feature not previously described in this syndrome. We believe this is the first reported case of PPGSS occurring in Brazil