1.
China Journal of Chinese Materia Medica
;
(24): 1083-1086, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-351840
RESUMEN
<p><b>OBJECTIVE</b>To investigate the effects of Siwu Tang on HFCL proliferation and protein expression of bone marrow stromal cells and to discuss molecular mechanism of enriching blood functions of Siwu Tang.</p><p><b>METHOD</b>MTT, flow cytometry and proteomics were used respectively to measure the effect of Siwu Tang on HFCL proliferation, cell cycle and proteinexpression.</p><p><b>RESULT</b>Siwu Tang can promote HFCL proliferation, increase proliferative index, up-regulate 12 kinds of proteins and down-regulate 5 kinds of proteins of HFCL.</p><p><b>CONCLUSION</b>Through promoting HFCL proliferation and acting on multipleprotein targets, the blood enriching function of Siwu Tang was exerted indirectly.</p>