[Effect of radiation leakage of microwave oven on rat's serum testosterone]

Since discovery of high frequency waves and their application in different industries, their adverse biological effects have been of great attention. Increased male fertility problems have suggested the possible role of microwaves in producing this disorder. Testes are active body tissues, which can be affected by these waves. Age of the patients at the time of the exposure can have important influence on the effect of these waves. Therefore, the aim of this study was to evaluate the effect of radiation leakage of microwave oven on rat serum testosterone at pre and post pubertal stages. In this study we used 18 mature [two months old] and 18 immature [one months old] rats. Mature and immature rats each were divided into control and experimental groups. Experimental groups were exposed to 2450 MHZ microwaves produced by a microwave oven, three times a day, each time for 30 minutes and control groups were kept in the laboratory under identical conditions in view of temperature and light. At the end of experiment blood was collected via heart puncture and serum testosterone was measured by RIA method. Collected data were analyzed by means of t-test. The result of this study showed that the level of serum testosterone in experimental group was less than that of control group in immature rats [P>0.05]. But in the mature rats, the serum testosterone level of experimental group was less than that of control group significantly [P<0.05]. Exposure to microwaves leakage of microwave oven resulted in decreased testosterone production by testes in mature rats which may be due to the direct effect of microwave on leydig cells or its indirect effect on pituitary and hypothalamus

Imaging findings of radiation enteritis

In this report the authors describe the imaging features of subacute and chronic radiation enteritis in two patients. Although surgery remains the definitive treatment of complicated chronic radiation enteritis, the potential role of interventional techniques that can be used for management of poor surgical candidates is discussed

Scanning electron microscopic study of visible light curing effects on the oral mucous membrane

The present investigation was undertaken on rats to demonstrate the structural changes that took place after the exposure of the gingiva to a dental visible light curing unit. Sixteen rats were irradiated and four were considered as controls. The mandibular right first molar was exposed to radiation for 40 seconds. The animals were classified into four groups [4 experimental and 1 control] and were sacrificed immediately, 2 days, 4 days and 2 weeks after exposure. Specimens were processed for ultrastructural and light microscopic investigations. The results indicate that emission from dental light curing units can affect the oral mucous membrane and may reduce its functional abilities

Ultrastructural changes in the irradiated liver of rats after different radiation schedules

Forty female albino rats were divided into 4 groups, 10 rats each. The first group was used as control. The second group received whole body irradiation as a single dose of 9 Gy. The third group was given 9 Gy as a single dose of the liver [right hypochondrium]. The fourth group received a fractionated liver dose of 9 Gy divided into 3 equal fractions with an interfraction time interval of 2 weeks [right hypochondrium]. The animals of the second group were sacrificed 2 weeks after irradiation. One half of the rats in the third and fourth groups were sacrificed after 2 weeks and the other half 3 months after irradiation. Using light [LM] and electron microscopy [EM], various grades of degenerative changes could be seen. It was concluded that hepatocytes may express, under certain circumstances and using EM, signs of early damages. It is not clear, however, that the morphological changes observed by EM reflect a change in clonogenic activity

Evaluation of cyclic adenosine monophosphate [cAMP] and nuclear estrogen receptor [ERn] in mammary tumors of female rats after irradiation and hormonal therapy

This study was designed to investigate the effect of hormonal treatment and irradiation on the level of cAMP and ERn in DMBA induced mammary gland carcinoma tissue of female rats. The results showed that tamoxifen has a better advantage in treatment of DMBA-induced mammary gland tumour of female rats than DES. The anti-regression of ERn level cAMP level in verapamil group explores the role of cAMP and calcium ion on the mechanism of ERn. The results with different single doses of gamma radiation revealed the positive relation between the cAMP values and the amount of single radiation dose but this relation is absent with ERn value

Reflexiones sobre la etiología de la leucemia / Raminisence about leukemia etiology

Se ha detectado un agrupamiento de 52 casos de leucemia y 22 de linfoma no-Hodgkin en niños, calculado en 10 veces lo esperado, en el área de la planta nuclear de Sellafield en Inglaterra; se lo ha relacionado con la exposición sostenida a radiaciones de los padres de estos niños antes de la concepción. Estas observaciones me recordaron experimentos que hicimos en la década del '60 con 32p en ratones BALB/c. Con dosis superiores a 40 *Ci inoculadas a madres durante la preñez, la cría resultó ser estéril, por daño de las espermatogonias en los machos y luteinización del ovario en las hembras. Además, el 45% de los animales desarrollaron leucemia con una latencia de 18 meses. En experimentos posteriores se indujo leucemia con diversos procedimientos, incluyendo la inoculación intraesplénica de leucemia/linfoma humanos, la inmunización con Sarcoma 180, rayos X, etc. Todos los animales leucémicos expresaban el virus de Gross, detectado por anticuerpos anti-G. Experimentos más recientes con estimulación antigénica crónica sugieren la siguiente secuencia: alorreactividad, autoinmunidad, leucemia. La explicación del mecanismo involucrado permanece controvertida. Inicialmente se habló de la activación del virus de Gross, luego del oncogenes eran celulares y no virales, se los incriminó de diferentes maneras. Recientemente, con el descubrimiento de los anti-oncogenes o genes supresores de tumor, se habla de una cascada de eventos génicos, tanto efectores como supresores

Valoración del riesgo ocupacional por exposición a campos electromagnéticos en trabajadores que aplican el tratamiento con diatermia / Assessment of occupational risk due to exposure to electromagnetic fields in workers applying the diathermy treatment

Se midieron los valores de intensidad de los campos eléctricos y magnético, generados durante la aplicación diatermia a pacientes en las áreas de fisioterapia de 7 hospitales. Se hicieron observaciones y se realizó una revisión bibliográfica. A partir de esa información se hizo una valoración del riesgo ocupacional en esos puestos de trabajo. Son brindadas recomendaciones para disminuir el riesgo

Electrocardiographic changes following radiation therapy for breast carcinoma

ECG changes were detected in 2 out of 40 [5%] selected females with carcinoma of the breast and receiving postoperative radiation therapy. None of the 20 patients with carcinoma of the right breast developed ECG changes following irradiation, while 2 patients out of 20 [10%] with carcinoma of the left breast showed inverted T-wave; in leads I, a VL and V2-V6 in one case and in V2-V3 in the other case, following postoperative irradiation. The site of the primary tumor, distribution of radiation fields, type of surgery and type of radiation energy [Co60 or DXR] were found to affect the volume and radiation dose reaching the heart

Influence of vitamin C administered after radiation

Postradiation administration of vitamin C was evaluated for its possible effects on reducing or reversing the effects of radiation. Stomach, duodenum, testes and bone marrow of male guinea pigs were examined for the effects of radiation e.g. degeneration, necrosis and cellularity. There was no significant difference in the effects of radiation between animals that received vitamin C and those that did not. The study, therefore, showed that vitamin C when given after exposure has no influence on the effects of radiation

Bone marrow dose from radiation treatment of cancer bladder

In this study the active marrow dose is calculated and measured for patients treated from cancer. Bladder represents the highest incidence among the other cancers in Egypt [21%] and where the pelvic region contains about 40% of the total active bone marrow in human body of age 40 years. Thermoluminescent dosimeters were used to measure the active marrow dose from two different techniques usually used in treating cancer bladder