Uterine rupture and labor induction with prostaglandins.

Uterine rupture in patients with labor induction with prostaglandin E2 application though uncommon is a very serious complication and preventable in obstetrics. We reported three cases of spontaneous uterine rupture following induction of labor with intracervical PGE2 gel administration in a dosage of 3-6 mg and two in whom labor was augmented with oxytocin infusion. To avoid such a complication, intracervical PGE2 gel administration should be started with a smaller dose and should augmentation with oxytocin be required careful evaluation and monitoring by a specialist is desirable.

Abruptio placentae y ruptura uterina en una paciente tratada con difenilhidantoina en el embarazo / Abruptio placentae and uterine rupture in a patient treated with diphenylhydantoin in pregnancy

Presentamos el caso de una paciente de 29 años, III gestas, I para, I aborto, controlada durante su tercer embarazo por crisis parciales complejas secundariamente generalizada, recibiendo tratamiento con difenilhidantoína sódica, 300 mg/día hasta la semana 37 y 400 mg/día luego, quien en la semana 38 del embarazo presentó abruptio placentae y ruptura espontánea del útero. Se revisa la literatura sobre el tema