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Rev. méd. Chile ; 130(9): 977-984, sept. 2002. tab
Artículo en Español | LILACS | ID: lil-323230

RESUMEN

Background: Short stature is the main feature of patients with Turner's syndrome. There is limited information regarding the spontaneous growth of these patients in Chile. Aim: To develop a specific growth chart for Chilean patients with Turner's syndrome. Material and methods: We retrospectively analyzed 668 height measurements from 85 Chilean girls, born after 1968, with 45XO karyotype (minimum 15 percent), and without an Y chromosome fragment. Patients with hormonal therapy, such as growth hormone or estrogen, except thyroid hormone replacement, were excluded. Results: The karyotypes were 60 percent 45XO, 25 percent 45XO, 46XX, and 15 percent other complex mosaics. The birth length was 46.8 ñ 2.1 cm. The final height of our patients was 138,20 ñ 7,0 cm. Conclusions: The final height achieved by our patients, is similar to Argentinian and Japanese patients, but is below the mean stature reported for Scandinavian and Northamerican patients who achieve a mean adult height of approximately 147 and 142 cm respectively. The birth length is also lower than that reported in those studies


Asunto(s)
Humanos , Adolescente , Femenino , Lactante , Preescolar , Trastornos del Crecimiento , Síndrome de Turner/fisiopatología , Síndrome de Turner/complicaciones , Síndrome de Turner/etnología
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