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Acta Pharmaceutica Sinica ; (12): 1258-1261, 2009.
Artículo en Inglés | WPRIM | ID: wpr-344098

RESUMEN

Two erythrodiol triterpene fatty esters, 3beta-dodecanoyl erythrodiol (1) and 3beta-tetradecanoyl erythrodiol (2), were isolated from Scorzonera mongolica. Their structures were elucidated on the basis of IR, MS and extensive 2D NMR spectroscopic analysis. Compound 1 was identified to be a new compound and 2 was confirmed to be a new natural compound. Their antitumor effects in vitro were evaluated with MTT and SRB assays, but compounds 1 and 2 only showed moderate cytotoxicities on A-549 cell line.


Asunto(s)
Animales , Humanos , Ratones , Antineoplásicos Fitogénicos , Química , Farmacología , Carcinoma Hepatocelular , Patología , Línea Celular Tumoral , Medicamentos Herbarios Chinos , Química , Farmacología , Leucemia P388 , Patología , Neoplasias Hepáticas , Patología , Neoplasias Pulmonares , Patología , Espectroscopía de Resonancia Magnética , Estructura Molecular , Plantas Medicinales , Química , Scorzonera , Química , Triterpenos , Química , Farmacología
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