RESUMEN
Abstract Cutaneous collagenous vasculopathy is a rare acquired idiopathic microangiopathy characterized by progressive development of diffuse asymptomatic telangiectasias and histologically by accumulation of collagen type IV around the affected vessels. It is diagnosed by its clinical history, confirmed by light microscopy with collagen-specific immunostaining. We report a case of a patient with extensive acquired telangiectasias on the left arm, clinically resembling unilateral nevoid telangiectasia. Dilated blood vessels with thickened walls were observed in the dermis. Immunohistochemistry with collagen IV antibodies revealed marked collagen deposition around the vessels, confirming the diagnosis. Transmission electron microscopy observed duplicate and triplicate vascular basal membrane associated with deposition of amorphous material around the membranes.
Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , Telangiectasia/diagnóstico por imagen , Enfermedades Cutáneas Vasculares/diagnóstico por imagen , Enfermedades del Colágeno/diagnóstico por imagen , Brazo , Telangiectasia/patología , Enfermedades Cutáneas Vasculares/patología , Enfermedades del Colágeno/patología , Colágeno Tipo IV/metabolismo , Microscopía Electrónica de Transmisión , MicroscopíaRESUMEN
Abstract: Juvenile xanthogranuloma is the most common form of non-Langerhans cell histiocytosis. It manifests clinically as a red-yellow papule, usually showing spontaneous remission. The diagnosis is based on clinical and histological findings. We report the use of dermoscopy ("setting sun" pattern) as an adjuvant tool in the diagnosis of juvenile xanthogranuloma in a female patient presenting with a 2-month history of a pre-auricular papule.