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1.
Biol. Res ; 47: 1-9, 2014. graf, tab
Artículo en Inglés | LILACS | ID: lil-710935

RESUMEN

BACKGROUND: Current study has been designed to evaluate the chemical composition of essential and fixed oils from stem and leaves of Perovskia abrotanoides and antioxidant and antimicrobial activities of these oils. RESULTS: GC-MS analysis of essential oil identified 19 compounds with (E)-9-dodecenal being the major component in stem and hexadecanoic acid in leaves. In contrast, GC-MS analysis of fixed oil showed 40 constituents with α-amyrin the major component in stem and α-copaene in leaves. The antioxidant activity showed the highest value of 76.7% in essential oil from leaves in comparison with fixed oil from stem (45.9%) through inhibition of peroxidation in linoleic acid system. The antimicrobial assay tested on different microorganisms (e.g. E. coli, S. aureus, B. cereus, Nitrospira, S. epidermis, A. niger, A. flavus and C. albicans) showed the higher inhibition zone at essential oil from leaves (15.2 mm on B. cereus) as compared to fixed oil from stem (8.34 mm onS. aureus) and leaves (11.2 mm on S. aureus). CONCLUSIONS: The present study revealed the fact that essential oil analyzed from Perovskia abrotanoides stem and leaves could be a promising source of natural products with potential antioxidant and antimicrobial activities, as compared to fixed oil.


Asunto(s)
Antiinfecciosos/química , Antioxidantes/química , Lamiaceae/química , Hojas de la Planta/química , Aceites de Plantas/farmacología , Tallos de la Planta/química , Alcanos/análisis , Alcanos/farmacología , Antiinfecciosos/farmacología , Antioxidantes/farmacología , Aspergillus/efectos de los fármacos , Bacillus cereus/efectos de los fármacos , Candida albicans/efectos de los fármacos , Pruebas Antimicrobianas de Difusión por Disco , Escherichia coli/efectos de los fármacos , Cromatografía de Gases y Espectrometría de Masas , Peroxidación de Lípido/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Éteres Metílicos/análisis , Éteres Metílicos/farmacología , Aceites Volátiles/química , Ácido Oleanólico/análisis , Ácido Oleanólico/análogos & derivados , Ácido Oleanólico/farmacología , Ácido Palmítico/análisis , Ácido Palmítico/farmacología , Triterpenos Pentacíclicos/análisis , Triterpenos Pentacíclicos/farmacología , Aceites de Plantas/química , Sustancias Reductoras/análisis , Sesquiterpenos/análisis , Sesquiterpenos/farmacología , Staphylococcus/efectos de los fármacos , Ácidos Esteáricos/análisis , Ácidos Esteáricos/farmacología
2.
Acta amaz ; 40(4): 711-718, dez. 2010. ilus, tab
Artículo en Inglés | LILACS, VETINDEX | ID: lil-570419

RESUMEN

Three coumarins, 5-methoxypsoralene, xanthyletin, and (-)-marmesin, have been isolated from the ethanolic extract of the stem of the Amazonian plant Brosimum potabile. The structures were determined on the basis of NMR analyses and by comparison with spectroscopic data in the literature. The analysis of the hexane fractions by GC-MS in EIMS mode suggested the presence of (1-methylpentyl)-benzene; α,α-dimethyl-4-(1-methylethyl)-benzenemethanol; 1-methyl-3,5-bis(1-methylethyl)-benzene; urs-12-ene; chola-5,22-dien-3ß-ol; cholesta-4,6-dien-3ß-ol; sitosteryl 9(Z)-octadecenoate; cholesta-5,22-dien-3ß-ol; cholesta-4,6,22-trien-3-one; and cholesta-4,22-dien-3-one. NMR data of other hexane fractions indicated the presence of 3ß-acetoxy-lup-12,20(29)-diene; 3ß-acetoxy-olean-12-ene; 3ß-acetoxy-urs-12-ene; and adian-5-ene. All these compounds are first described in B. potabile.


Três cumarinas, 5-metoxipsoraleno, xantiletina e (-)-marmesina, foram isoladas no extrato etanólico do cerne da planta amazônica Brosimum potabile. Suas estruturas foram determinadas a partir das análises por RMN e por comparação com dados espectroscópicos da literatura. As análises das frações hexânicas por CG/EM sugeriram a presença de (1-metilpentil)-benzeno; α,α-dimetil-4-(1-metiletil)-benzenometanol; 1-metil-3,5-bis(1-metiletil)-benzeno; urs-12-eno; cola-5,22-dien-3ß-ol; colesta-4,6-dien-3ß-ol; (9Z)-octadecenoato de sitosterila; colesta-5,22-dien-3ß-ol; colesta-4,6,22-trien-3-ona e colesta-4,22-dien-3-ona. Dados de RMN de outras frações hexânicas indicaram a presença de 3ß-acetóxi-lup-12,20(29)-dieno; 3ß-acetóxi-olean-12-eno; 3ß-acetóxi-urs-12-eno e adian-5-eno. Todos esses compostos foram identificados pela primeira vez em B. potabile.


Asunto(s)
Cumarinas/análisis , Moraceae/química , Triterpenos Pentacíclicos/análisis
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