Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Añadir filtros








Intervalo de año
1.
Indian J Exp Biol ; 1998 Apr; 36(4): 361-6
Artículo en Inglés | IMSEAR | ID: sea-56726

RESUMEN

Systemic administration of opioid peptides, methionine-enkephalin and beta-endorphin, chronically, lowered gonadotropin levels in plasma and had an inhibitory effect mainly on the testicular enzymes hyaluronidase, acid phosphatase and on incorporation of 3[H] thymidine in the tissue. When rats were similarly treated with opioid peptide antagonist naloxone and N-acetyl beta-endorphin antiserum, induced an opposite effect. This is either the direct effect of opioid peptides/antagonist on the gonads or it may be via the circulating levels of gonadotropin.


Asunto(s)
Animales , Relación Dosis-Respuesta a Droga , Masculino , Naloxona/administración & dosificación , Péptidos Opioides/administración & dosificación , Ratas , Ratas Wistar , Testículo/efectos de los fármacos , betaendorfina/administración & dosificación
2.
Braz. j. med. biol. res ; 20(6): 731-40, 1987. ilus, tab
Artículo en Inglés | LILACS | ID: lil-77425

RESUMEN

1. The effects of undernutrition during suckling and of post-training ß-endorphin administration on avoidance task were invstigated in adult rats. 2. young rats were undernourished from delivery until weaning (21 days) by feeding their mothers a diet conatining 8% protein (w/w). Mothers of well-nourished rats were fed a 20% protein diet. After weaning, both groups of rats were fed a 20% protein diet until 90-120 days if age, when they were subjected to behavioral sessions. 3. Acquistion was measured in training sessions and retention in test sessions 24 h after training. Beta-endorphin or salina (control) was injected ip immdiately after training. Rats were subjected to shuttle and step-down inhibitory avoidance sessions using footshock of 0.2 or 0.8 mA intensity. 4. Undernutrition during suckling caused hyperreactivity to 0.2 mA footshocks. Beta-endorphin caused amnesia to shuttle avoidance task only in normal rats trained with 0.8 mA. Foor-shocks. In the step-down inhibitory avoidance task, ß-endorphin was amnesic only for normal rats and only for 0.2-mA footshocks. Beta-endorphin was not amnesic in undernourished rats


Asunto(s)
Ratas , Animales , Masculino , Femenino , betaendorfina/administración & dosificación , Desnutrición Proteico-Calórica/complicaciones , Reacción de Fuga/fisiología , Retención en Psicología , betaendorfina/metabolismo , Electrochoque , Hipotálamo/metabolismo , Memoria/efectos de los fármacos , Ratas Endogámicas , Reacción de Fuga
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA