Sexual Nursing Care For The Postpartum Period And Its Impact On Sexual Dysfunction And Life Satisfaction Among Egyptian Women

@#Many couples experience postpartum period of decreasing sexual satisfaction. Postpartum sexual dysfunction is a very common and relevant clinical problem, with significant adverse effects on women's health. The aim of this study was to evaluate the impact of sexual nursing care for the postpartum period on sexual dysfunction and life satisfaction among Egyptian women. A quasi-experimental design was used to study 219 women selected using a purposive sample. The study was conducted in out-patients maternity clinic at Zagazig university hospitals, Sharkia Governorate, Egypt, between the periods from February 2019 to February 2020. Data was collected using three tools. The first: Structured interview questionnaire that consist from three parts, part one: socio demographic characteristics , part two obstetric history and part three sexual history, the second: Female Sexual dysfunction index (FSDI), and the third: Satisfaction with Life Scale (SWLS).Four session about sexual education was done. The Results showed an improvement in sexuality and life satisfaction after application of sexual nursing care for the postpartum period including kegel’s exercise, positioning and distractions techniques post intervention compared to pre intervention. The study concluded that sexual nursing intervention for postpartum period improve sexual functioning and create enjoyable intercourse and there was high positive correlation between sexuality and life satisfaction after implementation of the sexual nursing care intervention. The study recommended to provide counselling /training program about sexual nursing care intervention during postpartum period for nurses working in different health care settings.

potential protective and therapeutic effects of aloe vera juice on malathion induced hepatotoxicity in rabbits

the potential protective and therapeutic effects of Aloe vera juice against malathion induced hepatotoxicity were evaluated in this study. one hundred twelve young male rabbits were used ; they were allocated into two sets of experiments included rabbits treated for short [7 days] and long [21 days] periods. Animals of the first set [short period of treatment] were divided into eight groups; each consisted of four treated groups and four control groups [each treated group had its own control]. The animals of the first group were orally dosed with Aloe vera juice [0.84 ml/kg b. wt]. Rabbits of the second group were orally dosed with malathion [5 mg/kg b. wt.]. The third group animals were dosed orally with malathion concomitant with Aloe vera juice [this group served as the protective group]. Animals of the fourth group were dosed orally with malathion; for 7 days followed by Aloe vera juice for the same period [this group served as the therapeutic group]. The design of the second set [long period of treatment] was exactly similar to that of the short period experiments [divided into eight groups; four treated and four control groups] except the duration of treatment which extended to 21 days. Animals of the control groups of Aloe vera treated rabbits were dosed with distilled water, and those of malathion treated animals were dosed with the solvent of the insecticide. All the animals were sacrificed, blood samples were collected and the serum was used to determine the levels of hepatic enzyme markers: lactate dehydrogenase [LDH], aspartate aminotransferase [ASAT], alanine aminotransferase [ALAT] and alkaline phosphatase [ALP] as well as the total bilirubin. the results revealed that treatment of rabbits with malathion caused marked increase in the serum activity of LDH, ASAT, ALAT and ALP in treated rabbits. Administration of Aloe vera juice [in the protective and therapeutic groups] was found to be effective in lowering the elevated activities of these enzymes to approximate near normal levels for both the short and long periods of treatment, especially in the activity of LDH, ASAT and ALP. The present results suggested that Aloe vera juice has ameliorative effects against hepatotoxicity produced by malathion in the treated rabbits

potential protective and therapeutic effects of aloe vera juice against malathion induced haematological changes in rabbits

The potential protective and therapeutic effects of Aloe vera juice against malathion induced haematological changes in young rabbits [Oryctolagus cuniculus] were evaluated in this study. Rabbits were allocated into two sets of experiments short [7 days] and long [21 days] periods. Animals of each set were divided into eight groups; four treated groups and each treated group had its own control. The animals of the first group were orally dosed with Aloe vera juice [0.84 ml/kg b. wt.]. Rabbits of the second group were orally dosed with malathion [5 mg/kg b. wt.]. In the third group [the protective group] animals were dosed orally with malathion concomitant with Aloe vera juice. Animals of the fourth group [the therapeutic group] were dosed orally with malathion; for 7 days followed by Aloe vera juice for the same period. All the animals were sacrificed, blood samples were collected and used to determine the levels of hematological indices: red blood cells [RBCs], white blood cells [WBCs], haemoglobin [Hb], haematocrit [Hct], mean corpuscular volume [MCV], mean corpuscular haemoglobin [MCH] and mean corpuscular haemoglobin concentration [MCHC]. Rabbits treated with Aloe vera juice [group 1] showed insignificant change in WBCs count, MCH and MCHC after treatment for both periods. On the other hand, other parameters exhibited significant [RBCs count] and highly significant [Hb and Hct values] change in rabbits treated for the short period. The rabbits of the second group [treated with malathion] exhibited a marked increase in WBCs count, MCV and MCH values, while, the values of RBCs, Haemoglobin and Hct were decreased. The protective group [Group3] showed that the values of all the tested haematological parameters [except MCHC, in both periods of treatment, and WBCs count in the short period of treatment] recorded a significant change in rabbits treated for short [7 days] or long [21 days] periods. A marked recovery in RBCs count and MCH value was observed in rabbits treated for 21 days. Regarding to group 4 [the therapeutic group], it was found that in both terms the rabbits exhibited insignificant changes in the values of all the tested haematological parameters compared to their corresponding controls, except three parameters in which they recorded significant [WBCs count, MCHC] and highly significant [Hct] increase compared to their control values after the long period only. These observations indicated the ability of Aloe vera juice to improve the deleterious effects caused by malathion administration

Asthma is inversely associated with Helicobacter pylori status

The increase in asthma rates has been linked epidemiologically to the rapid disappearance of Helicobacter pylori, a bacterial pathogen that persistently colonizes the human stomach. Recent evidence indicates that, H. pylori may have protective effects on allergic diseases. The aim of this study was to explore the relationship between asthma and H. pylori infection in a population with high prevalence of H. pyloriinfection. One hundred and seventeen asthma cases were eligible for the study in addition to 86 non asthma cases as control. Pre and post - bronchodilator spirometry, assay of Total serum immunoglobulin E [IgE] by enzyme immunoassay technique [ELISA] and [14]C Urea Breath Test [UBT] were done. Out of 41 asthmatic cases with positive H. pylori were 22 patients had mild asthma, 14 had moderate asthma, and 5 only had severe asthma with statistically significant difference between them. The mean serum level of Total IgE was significantly higher [190.04 +/- 111.9] in patients group than control group [94.13 +/- 46.49] with p-value 0.000, while the mean UBT was significantly lower [325.85 +/- 261.35] in patients group than control group [1068.67 +/- 680.7] with p-value 0.000. AS regard pulmonary function tests [FEV1 and FVC], there was statistically significant difference between positive H. pylori asthmatic and negative H. pylori asthmatic. We demonstrate an inverse association between H. pylori and asthma in a population with a high prevalence of H. pylori

Effect of submersion injury on water safety practice after the event in children, Saudi Arabia

To bring to light issues surrounding water safety practices and the impact of such incidents on these practices in our community. We conducted a prospective observational study at King Abdul-Aziz Medical City, Riyadh, Kingdom of Saudi Arabia of all children <12 years of age presenting with submersion injury in the period between January 1999 through December 2004 noting the demographics and the pattern of water safety practices prior to and after event. A total of 29 patients were included. The majority of incidents took place in swimming pools. Water safety practices were lacking in most cases as evidenced by the fact that 87% of the victims were not properly supervised at the time of the event. None of swimming pools met the required safety regulations. Cardiopulmonary resuscitation knowledge was virtually nonexistent. The event did not have a positive impact on the water safety practices of the affected families. Submersion injury is also prevalent in land locked areas. Water safety practices are deficient in our community. Submersion injury was not enough to have a consistent positive impact on water safety practices of the affected families. Much can be carried out to improve water safety and save lives

Clinical usefulness of cystatin C concentration as a marker of early renal dysfunction in patients with cirrhosis of the liver

As preventive and renoprotective interventions are available, early identification of nephropathy is crucial, and there is a growing demand for a clinically convenient and reliable marker of renal function. Diagnosis of impaired renal function is of particular importance in patients with cirrhosis of the liver. Moderately reduced renal function may be missed by the conventional parameters. Cystatin C is an endogenous marker of glomerular filtration rate independent of muscle mass. Therefore, the aim of this study was to investigate the value of serum cystatin C concentration for the detection of moderately impaired renal function in patients with different stages of cirrhosis in comparison with the conventional methods. Eighty seven patients with cirrhosis were included in this study; All cases in this work had been examined clinically and they are scored according to Child-Pugh score. Calculation of creatinine clearance [CrCl] by determining its concentration in timed urine collections and simultaneously in blood were done for all the patients. All blood samples were obtained on the day of urine collection for CBC, LFTs, pro-thrombin time, serum electrolyte, creatinine, urea, creatinine clearance and Cystatin C concentrations. The patients then divided into two groups depending upon the results creatinine clearance: [groupl] normal creatinine clearance group [creatinine clearance >/= 70 ml/min; n=50] and [group2] reduced creatinine clearance group [creatinine clearance 40n69 ml/min; n=37]. There was no significant difference in urea concentration between the two groups [30.7] group 2 versus [28.3] mg/100 ml, group 1. While serum Cystatin C concentrations [mean [SD]: 1.32 [0.51] v 1.03 [0.34] mg/1 [p=0.008] and creatinine concentrations 1.03 [0.52] v 0.86 [0.22] mg/100 ml [p=0.03] were higher in group 2 than in group 1. To confirm the diagnostic advantage of Cystatin C over creatinine and urea. Receiver-operator characteristics [ROC] shows at equal specificity, the sensitivity of cystatin C was increased almost throughout the ROC plot. At cut off concentrations of 1.0 mg [Cystatin C], 0.8 mg/100 ml [creatinine] and 27 mg/100 ml [urea],cystatin C exhibited significantly higher sensitivity than creatinine and urea [70%, 45.2%, and 43.9%; respectively p<0.05], Specificity and efficiency were not significantly different between parameters. The sensitivity of Cystatin C [88.5%] tended to be higher than that of creatinine [62.0%] and urea [55.3%] at equal specificity of [60%] in Child-Pugh class C patients. The results demonstrated that the diagnostic accuracy of plasma Cystatin C was better than plasma creatinine in identifying liver cirrhotic patients with reduced glomerular filtration rate. particularly with Child-Pugh class C patients, for early diagnosis of renal dysfunction

Evaluation of the clinical usefulness of blood cultures in hospitalised patients with community acquired pneumonia

Pneumonia that develop outside the hospital is considered CAP. Bacteremia is a serious clinical condition and can lead to death. To give the best chance for effective treatment and survival, a BC is done as soon as an infection is suspected. The aim of this work is to evaluate blood culture in patients with community acquired pneumonia and to correlate it with clinical response to medical treatment. This study was conducted on 50 patients; 36 males and 14 females. Sputum and blood samples are collected, transported and processed immediately in the laboratory by a technician under the supervision of a bacteriologist where blood and sputum culture were done. This study revealed that Strept. pneumoniae and H. infleunzae represented 38% of positive cultures, while Staph aureus and E.coli represented 30%. In conclusion, there was a little clinical usefulness of both sputum and BCs in the management of CAP and the empirical therapy is important as it gave 96% success without any antibiotic modification after the results of blood and sputum cultures have been available

Granulocyte macrophage colony stimulating factor: role in induction of monocyte CD14 receptor and adhesion molecules expression in chronic liver diseases

This study included 36 chronic liver disease [CLD] patients who suffered from viral hepatitis and / or schistosomiasis and 12 age and sex matched healthy individuals who represent the control group. The study aimed at clarifying the role of rhGM-CSF on the release of sICAM-1 and sCD14 from PBMNC. According to the severity of liver disease, patients were classified to Child A, B and C groups. All patients and controls were subjected to thorough history taking and clinical examination, a full routine laboratory investigation including hemogram, liver function tests and hepatitis markers. PB mononuclear cell culture was performed to all the study groups with and without the addition of rhGM-CSF to the culture media. Afterwards, slCAM-1 and sCDl4 were measured in culture supernatant fluid using ELISA technique, Levels of sICAM-1 in culture supernatants with and without addition of rhGM-CSF showed significant progressive increase with advancement of CLD which may reflect the increase ofsICAM-1 in sera of CLD patients with progression of the disease. As well, the addition of rhGM-CSF to PBMNC culture resulted in a significant reduction of sICAM-1 level in culture supernatants in control and patients groups in comparison to its level without the addition of rhGM-CSF. There was a significant progressive increase in sCD14 level with the advancement of the disease. The increase in sCD14 level with and without addition of rhGM-CSF was significant in all patients groups in comparison to the control group. As well, the addition of rhGM-CSF to culture media led to significant reduction of sCD14 concentration in supernatants in control group and in each of the patients groups in comparison to their levels without the addition of rhGM-CSF. It can be concluded that rhGM-CSF might be considered as one of the potential future tools against defective monocyte functions in CLDs. Using rhGM-CSF to improve monocyte functions will be associated with reduction of sICAM-1 and sCD14 levels which might be implicated or contribute to liver pathology

IgG isotypes in Schistosomiasis patients before and after praziquantel

This work evaluated circulating anti-SWAP IgG1 and IgG4 in patients with active S. Mansoni infection before and after PZQ and its correlation to clinical, laboratory and sonographic data. The main complaints were abdominal discomfort, pain, tensmus and bleeding per rectum, which decreased progressively after PZQ. The results indicated that anti-SWAP IgG1 and IgG4 were significantly higher in patients than controls. The results also showed a progressive significant decrease in the level of circulating anti-SWAP IgG1 after treatment, a decrease of IgG4 three months after treatment and a decrease in the egg count after therapy. But, no significant difference in IgG1 or IgG4 was noticed between male and female patients before and after treatment. There was no significant difference in IgG1 or IgG4 in patients having GIT manifestation and organomegalic patients and/or asymptomatic patients. Also, there was no significant difference in IgG1 or IgG4 between patients with grade 0, grade I and grade II periportal fibrosis. The sensitivity of ELISA IgG1 was 73.3% and specificity was 80%, while of ELISA IgG4 was 80%. Enlarged liver and/or spleen, periportal fibrosis and dilated PV detected by ultrasonography were more among patients than controls. There was no significant difference in hematological parameters and liver function tests between patients and control groups. The study showed that ELISA is sensitive and specific for IgG1 and IgG4. Anti- SWAP IgG1 and IgG4 are useful means in diagnosis and cure and consider as parameters for evaluating cure. Follow up of anti-schistosomal IgG1 and IgG4 is useful for assessment of treatment

Effect of different factors including gamma radiation on the growth and aflatroxin producing of Aspergillus flavus in sesame seeds.

Sesame seeds were inoculated with spore suspension of aflatoxigenic isolate of A. flavus. The effect of different moisture content levels on total A. flavus count was studied. The chemical quality attributes of inoculated sesame seeds containing different moisture contents were also investigated. The effect of moisture content, incubation temperature, incubation period, inoculum level and radiation on the aflatoxin production by A. flavus on sesame seeds was investigated. Sesame seeds were inoculated with aflatoxigenic A. Flavus, then irradiated with different irradiation doses. It was found that irradiation decreased aflatoxin production in seeds, this decrease was proportional with irradiation dose. Aflatoxin production was completely prevented by an irradiation dose of 2.5 kGy in inoculated sesame seeds, even under the most proper conditions for the growth of this fungus

Comparison of Tumor markers, alpha feto protein and carcinoembryonic antigen [C.E.A] with Alkaline phosphatase in patients with gastrointestinal tumors

Seven CEA, alpha-fetoprotein and alkaline phosphatase have been assayed in 32 patients with gastrointestinal cancers. CEA proved to be the valuable marker in determining the prognosis of colon, stomach and pancreatic cancers. In each case, alkaline phosphatase and alpha- fetoprotein were non diagnostic of 25 colon cancer patients, 12 had surgical treatment, CEA showed a fall to normal values in 10 cases [8 had radiotherapy]

Hepatic fibrosis in hamsters experimentally infected with S mansoni

Adult males Schistosoma mansoni were detected in the liver of experimentally infected hamsters induced a lesser intense granulomatous reaction than that induced by immune complex formation