[Toxic epidermal necrosis syndrome after taking Phenytoin; a case report]

Introduction: the toxic epidermal necrosis syndrome is defined as severe skin and mucosal reactions which usually appears by some drugs such as phenytoin. Case Presentation: a 35-year-old man who consumed phenytoin hospitalized due to diffuse mucocutaneous lesions and bullous lesions. After diagnosing its etiology, therapeutic actions were done similar to severe burns which led to improvement of wounds and discharging from the hospital.

Conclusion: finding the etiology of every disease is crucial step in its treatment. When the disease is caused by drug, it is necessary to discontinue immediately consumption of this and start treatment.

[Hepatobiliary dysfunction in patients with inflammatory bowel disease]

A high percent of patients with inflammatory bowel diseases [IBD] experience non intestinal symptoms. Many studies demonstrated that hepatobiliary disorders are the most common. Corresponding disorders consist of primary sclerosing cholangitis, non alcoholic steatohepatitis [NASH], biliary stones, pericholangitis, autoimmune hepatitis, liver amyloidosis, liver abscess, liver granuloma, hepatocellular carcinoma and primary biliary cirrhosis. However most studies concentrate on identifying primary sclerosing cholangitis, the most dreadful complication of IBD, other disorders like NASH and biliary stones are common and because of the similarity of symptoms to the primary disease may be ignored. In this article we review these disorders