Résumé
One hundred thirty-four lung cancer cases who were histologically proven in life and who had chest x-rays at time of initial diagnosis were entered into this retrospective study covering the period from January 1, 1979 to April 30, 1985The major histologic subtype of lung cancer in this study were similar to those cited by foreign literatures, namely epidermoid cell cancer (37). Adenocarcinoma (25), small cell cancer (20) and large cell cancer (5). By frequency and odds ratio, squamous cell and adenocarcinoma histologies presented with a peripheral radiographic location two times more than with a central location. On the other hand, small cell cancer histology was three times more associated with central radiogaphic presentation. Large cell cancer histology showed to be either centrally or peripherally located without preference. (author)
Résumé
The efficacy and tolerability of the combined scheme of administering high dose medroxyprogesterone acetate in advanced breast cancer is evaluated.
Sujets)
Administration par voie orale , Sujet âgé , Antinéoplasiques/administration et posologie , Tumeurs du sein/traitement médicamenteux , Femelle , Humains , Injections musculaires , Médroxyprogestérone/administration et posologie , Acétate de médroxyprogestérone , Adulte d'âge moyenRésumé
Twenty-two patients with advanced or recurrent cancer of the cervix treated with cis-platinum, adriamycin and cyclophosphamide were evaluated. Nine of 22 (41% achieved objective response (2 CR + 7PR), 9/22 (41%) stable disease, 4/22 (18%) progressive disease. The mean duration of response was 24.6 weeks, with a range of 18-28 weeks. Patients with poorly differentiated histologic grade and without previous treatment had better response rates. Responders had longer survival (mean 63.5 + weeks) than nonresponders (mean 30.5 weeks). Commonly encountered toxicities were alopecia, nausea and vomiting, and leucopenia, which were all tolerable.