Mirazid alone or combined with paromomycin in treating Cryptosporidiosis parvum in immunocompetent hospitalized patients

Sixty cryptosporidiosis patients from Mansoura University Hospitals, 36 males and 24 females, with age from few months to ten years [mean age 6.1] were divided into three cross-matched groups of 20 patients each. All patients received the glutamine-based oral rehydration solution with 111 mmol/1 glutamine, 20 mg zinc acetate once a day and vitamin A supplementation [200,000 IU] once a day for 2 weeks. For cryptosporidiosis treatment, Gl received Mirazid [10mg /kg for 2 weeks], G2 received Paromomycin [500 mg qid for 2 weeks], and G3 received a combination of Mirazid [10mg/kg] and Paromomycin [500 mg] for two weeks. The result was assessed according to the scales: 0= no improvement, 1= symptoms began improvement [reduction of diarrhea frequency and stool volume, less abdominal pain, less nausea and vomiting], 2= diarrhea eradication, 3= weight gain, 4= oocyst counts reduction, 5= reduction in diarrhea and oocyst counts, 6= eradication of diarrhea and oocysts. G3 showed significantly higher difference than Gl and G2 in the 1[st] week [p=.036, 0.025 respectively], no significant difference in 2[nd] week, a significantly higher difference than in Gl [0.003], and G2 [0.006] in 3[rd] week, and a significantly higher difference than Gl [0.014], and G2 [0.01] in 4[th] week, but without significant differences in oocyst shedding in the 3 groups

Zoonotic hydatidosis in donkeys: post mortum examination in the Zoo, Giza, Egypt

A total of 17 out of 160 donkeys slaughtered had hepatic hydatidosis as proved macroscopically and microscopically. The epidemiology of zoonotic echinococcosis/hydatidosis was reviewed and discussed

Helminthes of synanthropic rodents [rodentia: muridae] from Dakahlia and Menoufia, Egypt

A cross-sectional survey was conducted to monitor and compare the prevalence of helminthes in rodents from Dakahlia and Menoufia governorates. The domestic rodents [271] were Rattus norvegicus, Rattus rattus frugivorous, Rattus r. alexandrinus, and Mus musculus. The overall prevalence of helminthes was 52.8%. In Dakahlia, 72/145 rats [49.6%] were infected. The highest prevalence of infection was in R. r. frugivorous 43 [60.4%], then R. r. alexandrinus 44 [47.7%], R. norvegicus 38 [44.7%], and the lowest was M. musculus 20 [40%]. In Menoufia, 71/126 rats [56.3%] were infected. The highest prevalence of infection was in R, r. frugivorous 36 [77.7%], then M. musculus 27 [48.1%], R. norvegicus 23 [47.8%], and the lowest was in R. r. alexandrinus 40 [47.5%]. A total of 24 species of helminthes [11 trem-atodes, 4 cestodes and 10 nematodes] were identified among the 271 rodents. The commonest trematode was Mesostephanus aegypticus followed by Stictodora tridactyla. The commonest cestode was Hym-enolepis diminuta followed by Taenia taeniaformis. The commonest nematode was Capillaria hepatica followed by Trichurus muris. Given the zoonotic potential of rodents' parasites and since several residential, commercial, and agricultural sites exist in the examined geographic areas, the potential health risk should not be ignored

Nematode and water pollution in Eastern part of Nile Delta

The examination of some represented water sites revealed the presence of larvae and eggs of the nematodes infecting man and animals. Eggs in a descending order of abundance were Trichostrongylus, Toxocara canis, T. Vitulorum and Ascaris sp., then Trichocephalus and Ancylostoma sp. Larvae in a descending order were Strongyloides, Trichostrongylus and Ancylostoma sp. Contaminated or polluted water plays an important role as nematode-borne source