Résumé
Background: Glucose-6-phosphate dehydrogenase deficiency is an X linked recessive disorder expressed mostly in males. It is the most common enzyme deficiency worldwide, causes a spectrum of disease including neonatal hyperbilirubinemia, acute hemolysis, and chronic hemolysis
The aim of the study was to determine prevalence, risk factors of G6FD deficiency and its symptoms among general population of Dammam, Eastern Province of Saudi Arabia
Methods: A cross-sectional study was conducted during the period from 1 March 2016 to 30 July 2017. Data was collected from 182 individuals. Systematic random sampling technique was followed. Data was collected by using predesigned online questionnaire
Results: The overall prevalence of favism was 17%, of them, 67.7% were females and 32.3% were males. 15.2% of cases and 26.9% of the total sample had family history of the disease. Among the studied cases, 48.4% complained of pallor, 45.2% headache, 45.2% drowsiness, 12.9% nausea, 32.3% back pain, 64.5% tiredness, 25.8% abdominal pain, 38.7% discoloration of urine, 29% foot pain, 16.1% low grade fever and 19.4% complained of jaundice. Regarding risk factors of favism; 32.3% reported excess beans intake, 12.9% antibiotic intake and only 9.7% reported bacterial or viral infection
Conclusions: Glucose-6-Phosphate Dehydrogenase deficiency is a common disorder as it affects 17% of the study population of Dammam, Eastern Province of Saudi Arabia. It was more common in females than males. Health education sessions and further epidemiological studies are required because early detection and prevention is the key strategy for successful management and control of this genetic disease
Résumé
Background: Obesity often coexists with hypertension [HTN] and a linear relationship between blood pressure [BP] values and weight was observed
Objective: The aim of this study was to determine the prevalence rate of prehypertension and hypertension and to estimate the coexistence of prehypertension and hypertension and obesity in young adults in Arar, Saudi Arabia
Materials and Methods: This was a cross sectional study. The study subjects were selected from health young adults attending 5 randomly selected primary health care centers in Arar city, the capital of the Northern Province of KSA. Participants were given a predesigned and pretested questionnaire to collect the relevant data
Results: Among the studied participants, Fifty [52.1%] of females and 58.8% of males were pre-hypertensive and 1.5% from males were hypertensive. 37.9% of the studied participants were obese and same percentage were overweight. 18.2% of obese were hypertensive or pre-hypertensive and 40.9% of overweight were hypertensive or pre-hypertensive. While 3% of the underweight were hypertensive or pre-hypertensive and 3% were not [P<0.05]
Conclusion: In young adults in Arar, KSA. 37.9% of the studied participants were obese and same percentage were overweight. About half of females and more than half of males were pre-hypertensive and small percentage of males were hypertensive. Obesity was associated with pre-hypertension and hypertension. So education sessions should be carried out to educate the public specially adolescents and young adult population