RÉSUMÉ
Teeth erupting at birth are referred to as natal teeth. It is a common and benign finding in the neonatal period. However, they may be associated with genetic syndromes like Ellis Van Creveld syndrome and Hallermann-Streiff syndrome. We report here a case of natal teeth in an infant with congenital hypothyroidism.
Sujet(s)
Hypothyroïdie congénitale/complications , Hypothyroïdie congénitale/diagnostic , Hypothyroïdie congénitale/thérapie , Épiphyses (os) , Humains , Nourrisson , Nouveau-né , Mâle , Mandibule , Dents natales , Dépistage néonatal , TibiaSujet(s)
Taille , Enfant d'âge préscolaire , Créatinine/sang , Diagnostic différentiel , Diagnostic précoce , Troubles de la croissance/diagnostic , Troubles de la croissance/étiologie , Humains , Hypertension artérielle/étiologie , Défaillance rénale chronique/complications , Défaillance rénale chronique/thérapie , Tests de la fonction rénale , Pâleur/diagnostic , Pâleur/étiologie , Dialyse rénale/méthodes , Insuffisance respiratoire/diagnostic , Insuffisance respiratoire/étiologie , Appréciation des risquesRÉSUMÉ
Objective. To identify risk factors associated with Persistent diarrhea (PD) and deaths due to PD. Methods. This prospective case control study included 60 children with PD (cases) and 60 children (controls) with acute diarrhoea (AD). Detailed history, examination and appropriate investigations were done for all children. Crude Odds ratio was calculated for each risk factor by univariate analysis and adjusted odds ratio was calculated by multivariate logistic regression. Results. Prior antibiotic use, steroid use, anemia, vitamin A deficiency, malnutrition, LRI, UTI, oral candidiasis, and hyponatremia, were statistically significant risk factors by univariate analysis. Prior antibiotic use, vitamin A deficiency, malnutrition and LRI were independently associated with PD by multivariate logistic regression analysis. The risk factors for mortality were stool frequency more than 10 times per day, severe malnutrition, oral candidiasis, hypoalbuminemia and HIV positivity. Conclusions. The presence of these risk factors should alert the clinician to take appropriate measures, to decrease the mortality.
Sujet(s)
Anémie/complications , Antibactériens/usage thérapeutique , Études cas-témoins , Enfant , Enfant d'âge préscolaire , Maladie chronique , Diarrhée/traitement médicamenteux , Diarrhée/étiologie , Diarrhée/mortalité , Femelle , Humains , Hyponatrémie , Nourrisson , Modèles logistiques , Mâle , Malnutrition/étiologie , Analyse multifactorielle , Odds ratio , Études prospectives , Infections de l'appareil respiratoire , Facteurs de risque , Carence en vitamine A/complicationsRÉSUMÉ
Hyperinsulinemic hypoglycemia is the most common cause of persistent hypoglycemia in infancy. While most of the cases are sporadic more than 100 mutations have been reported in the familial type. The authors report a case of familial hyperinsulinemic hypoglycemia with homozygous T294M mutation of the KCNJ11 gene, which responded to diazoxide therapy.
Sujet(s)
Antihypertenseurs/usage thérapeutique , Hyperinsulinisme congénital/traitement médicamenteux , Hyperinsulinisme congénital/génétique , Diazoxide/usage thérapeutique , Femelle , Homozygote , Humains , Inde , Nouveau-né , Mutation , Canaux potassiques rectifiants entrants/génétiqueRÉSUMÉ
OBJECTIVE: To study if different forms of clinical presentation of tuberculosis in children are associated with a different type of tuberculin reaction. METHODS: This cross sectional study, describing Tuberculin skin testing (TST) responses in 268 children (134 cases and 134 controls) less than 12 yr of age was carried out over a period of 18 months at JIPMER, a tertiary care referral hospital in Pondicherry, India. The qualitative and quantitative TST responses in various clinical forms of Tuberculosis were analysed. RESULTS: Koch's and Listeria variants were more common in children with TB Lymphadenitis and Pulmonary TB respectively. 10% of the study children with TB meningitis were tuberculin negative. CONCLUSION: Qualitative TST responses are non-homogeneous among the various clinical types of childhood tuberculosis. They are not a correlate of protective immunity with little or no prognostic significance.
Sujet(s)
Vaccin BCG , Enfant , Enfant d'âge préscolaire , Humains , Nourrisson , Test tuberculinique , Tuberculose/diagnosticRÉSUMÉ
We report acute onset quadriplegia in a ten year old boy associated with basal ganglia lesions due to biotin deficiency. Prolonged raw egg consumption was identified as predisposing factor for biotin deficiency. Treatment with biotin resulted in remarkable recovery.
Sujet(s)
Affections des ganglions de la base/diagnostic , Biotine/déficit , Enfant , Oeufs/effets indésirables , Humains , Imagerie par résonance magnétique , Mâle , Tétraplégie/traitement médicamenteux , Carence en vitamines B/diagnosticRÉSUMÉ
The study was conducted to identify the problems related to feeding of children post tsunami in four villages in Pondicherry. Data were collected from 100 randomly chosen families who had an infant or a young child below 3 years of age during Tsunami. Informants were the mothers. In the population studied, 30% mothers did not exclusively breast feed for 6 months; 58% bottle fed their children and 51% fed their infants with commercial formula. The occurrence of diarrhea was three times higher among children who were fed with free breast milk substitutes (BMS) than in those who were not fed with the same. Those populations, wherein a pre-existing tradition of artificial feeding is present, infants are at further risk during a crisis situation like Tsunami. Breast feeding practices need strengthening even in routine conditions to tackle a disaster rather than intervention after the disaster.