Résumé
To establish a successful live-related kidney transplantation programme in Libya and to bring down healthcare costs in management of patients with end-stage renal disease. The transplant programme was launched on 17th August, 2004 and 135 patients have been transplanted since then till 17th August, 2007. The donors and recipients were screened thoroughly prior to transplant. Recent surgical techniques were employed during transplant procedure. Close monitoring of both donors and recipients was undertaken in post-transplant period. Our immunosuppressive protocol was cyclosporine based. Both donors and recipients were followed up in the transplant out-patient clinic. Among 135 accepted pairs, donors and recipients were genetically-related in 133 cases [98.5%] and emotionally related in two cases. Mean donor age was 37 +/- 9.5 [range 18-56 years]. Recipient age was significantly lower with 37 +/- 13.6 years [range 7-67 years]. In all recipients, 95[70.4%] were males and 40[29.6%] were females while in donors, 102[75.6%] were males and 33[24.4%] females. The most common donor-recipient relationship was brother-to-brother. The HLA-matching was either identical or one haplotype match. There was no early or late surgical mortality in donors. Delayed graft function was seen in 3[2.2%], acute rejection in 6[4.4%] and post-transplant infections were seen in 8 patients[5.9%]. Urinary tract infection was seen in 6 patients[4.4%] and pneumonia in 3 patients [2.2%]. Post-surgical complications included ureteric kink in 2[1.5%] and anastomotic urine leak in 4[3.0%]. Graft survival in 36 months was seen in 130 patients [96.3%] while patient survival in the same period was 126 patients [93.3%]. The National Organ Transplant Programme in Libya has been a very successful programme with its results better than most middle-eastern programmes and comparable to international levels