Erratum: Associations between Dietary Allium Vegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study / 한국유방암학회지

This article was initially published on the Journal of Breast Cancer with a misspelled author name and affiliation of the seventh author.

Associations between Dietary Allium Vegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study / 한국유방암학회지

PURPOSE: The protective effect of Allium vegetables against carcinogenesis has been reported in experimental studies particularly focusing on the gut. Therefore, we conducted a hospital-based matched case-control study to explore the association between dietary Allium consumption and risk of breast cancer among Iranian women in northwest Iran. METHODS: A validated, quantitative, food frequency questionnaire was completed in 285 women (aged 25–65 years old) newly diagnosed with histopathologically confirmed breast cancer (grade II, III or clinical stage II, III) in Tabriz, northwest Iran, and the completed questionnaires were included in an age- and regional-matched hospital based-control study. The odds ratios (ORs) and 95% confidence intervals (95% CI) were estimated using conditional logistic regression models. RESULTS: Multivariate analysis showed that there was a negative association between the consumption of raw onion and risk of breast cancer after adjustment for covariates (OR, 0.63; 95% CI, 0.40–1.00); however, this association was insignificant. On the other hand, there was a positive association between consumption of cooked onion and risk of breast cancer, after adjustment for covariates (OR, 1.54; 95% CI, 1.02–2.32). However, reduced risk of breast cancer was associated with higher consumption of garlic and leek with adjusted ORs of 0.41 (95% CI, 0.20–0.83) and 0.28 (95% CI, 0.15–0.51), respectively. CONCLUSION: Our findings suggest that high consumption of certain Allium vegetables, in particular garlic and leek, may reduce the risk of breast cancer, while high consumption of cooked onion may be associated with an increased risk of breast cancer.

Factors associated with Limb salvage following complex blunt popliteal injury

The purpose of this study is to report management techniques and factors associated with early limb salvage following high risk popliteal vascular injury. Additionally controversial aspects of popliteal vascular injury management unique to an Iranian trauma center are discussed. A retrospective analysis was conducted of prospectively collected data Ji.om Tabriz Medical Trauma Center. Patients were divided into two study groups: Group 1 Limb salvage and Group 2 Amputation. Subgroup analysis consisted of university analysis comparing the Group land Group 2 as well as multivariate analysis examining factors associated negatively and positively with the primary endpoint, limb salvage. Sixty of the patients [97%] were male, two female [3%]; the mean age was 34.years [16-49 years].The overall amputation rate in the present study was 23 amputations [37%].On logistic regression analysis, significant [P<0.05] independent factors associated negatively with limb salvage were combined tibia and fibula fracture [OR 0.133; CI 0.01 7 -1.01 8], concomitant artery and vein injury [OR 0.039; CI 0.004- 0.407], ligation of venous injury [OR 0.326; CI 0.161 - 0.660], lack of back flow after Fugarty catheter thrombectomy [OR 0.129; CI 0.023-0.729], while repair of popliteal artery and vein injury [OR 2.81; CI 2.22 -6.53] when present was associated with improved early limb salvage. Expeditious recognition of vascular injury, transport to repair and repair of associated venous injury when possible are necessary to optimize limb salvage. A low threshold for timely amputation when limb salvage is not possible is important to prevent life-threatening complications