Exercise testing and risk assessment of pulmonary hypertension

Managing pulmonary hypertension (PH) involves approaches to relieve symptoms, slow disease progression, and improve patient outcomes. Advances in treatment strategies, risk assessment methods, and lifestyle adjustments have significantly improved PH care. While PH has no cure, treatment options are available to alleviate symptoms, extend life expectancy, and slow disease advancement. Tailoring treatment strategies based on the type and severity of PH as individual patient response and tolerance is crucial. The main goals include alleviating symptoms, enhancing quality of life, improving capacity, and increasing survival rates. Diagnosis and management require evaluation and regular follow-up due to the complexity of PH treatments. Different medical approaches play a role in symptom relief. Improving overall system function. Oxygen therapy and procedures such as septostomy or lung transplantation may be warranted, contingent on disease severity. Lifestyle modifications, encompassing exercise training, smoking cessation, and weight management, complement pharmacological interventions. Risk assessment tools, typified by the REVEAL risk score, have revolutionized PH care by facilitating personalized therapeutic approaches. Genetic factors are increasingly considered, heralding a new era in tailored treatment. While challenges persist, ongoing research endeavors promise.

Risk factors and screening benefits in pregestational and early gestation diabetes

Gestational diabetes is one of the most widespread complications of pregnancy posing a serious clinical and public health challenge. Globally, 16.5% of pregnancies are affected by the gestational diabetes, and this percentage is expected to rise as the obesity pandemic spreads. It has severe short-term and long-term negative health effects on both the mother and the child, which emphasizes the importance of identifying the risk factors for gestational diabetes and taking steps to prevent the illness. Gestational diabetes occurs when pregnant women who have never been diagnosed with diabetes experience chronic hyperglycaemia caused by impaired glucose tolerance. Obesity, physical inactivity, multiparity, family history of diabetes mellitus, certain ethnicities, birth of a previous macrocosmic child are all risk factors for gestational diabetes. Maternal cardiovascular disease, type 2 diabetes, macrosomia, and difficulties in delivery are all some of the complications of gestational diabetes. Additionally, there is a longer-term risk for the child to develop obesity, type 2 diabetes, and cardiovascular disease. Screening and diagnostic tests for gestational diabetes are essential to identify the women who are at risk for developing gestational diabetes and thereafter reduce or eliminate the risk of unfavourable outcomes for both mother and child associated with gestational diabetes. Oral glucose tolerance test is the widely accepted screening test conducted between 24-28 weeks of pregnancy for the diagnosis of gestational diabetes. The purpose of this research is to review the available information about risk factors and screening benefits in pregestational and early gestational diabetes.