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Braz. j. infect. dis ; 17(5): 573-578, Sept.-Oct. 2013. tab
Article Dans Anglais | LILACS | ID: lil-689883

Résumé

Methicillin-resistant Staphylococcus aureus has emerged as a pathogen associated with community-acquired infections worldwide. We report the spectrum of community-acquired S. aureus infections and compare the patients infected with methicillin-susceptible or methicillin-resistant strains among patients aged <20 years. Overall, 90 cases of community acquired S. aureus were detected in an 11-year period. Clinical and microbiological data were registered. Fifty-nine (66%) patients were male and the median age was two years. The majority (87%) of the patients were hospitalized and chronic underlying illnesses were detected in 27 (30%) cases. Overall, 34 (37.8%) patients had skin/soft tissue infections and 56 (62.2%) patients had deep-seated infection. Four (5.1%) patients were transferred to the intensive care unit and two (2.6%) died. Complications were detected in 17 (18.9%) cases, such as pleural effusion (41.2%), osteomyelitis (23.5%), and sepsis (17.6%). Six (6.7%) methicillin-resistant strains were detected. Patients infected with methicillin-susceptible or methicillin-resistant strains had similar baseline characteristics and treatment outcomes. Approximately 93% of the cases received systemic antibiotics, out of which 59 (65.5%) used oxacillin or cefalotin. Both methicillin-susceptible and methicillin-resistant S. aureus strains resulted in morbidity and death among children in this setting where methicillin-resistant strains are infrequent.


Sujets)
Enfant , Enfant d'âge préscolaire , Femelle , Humains , Nourrisson , Mâle , Antibactériens/usage thérapeutique , Infections à staphylocoques/microbiologie , Staphylococcus aureus/effets des médicaments et des substances chimiques , Antibactériens/pharmacologie , Brésil/épidémiologie , Études de cohortes , Infections communautaires/traitement médicamenteux , Infections communautaires/épidémiologie , Infections communautaires/microbiologie , Tests de sensibilité microbienne , Staphylococcus aureus résistant à la méticilline/effets des médicaments et des substances chimiques , Staphylococcus aureus résistant à la méticilline/isolement et purification , Études rétrospectives , Indice de gravité de la maladie , Infections à staphylocoques/traitement médicamenteux , Infections à staphylocoques/épidémiologie , Staphylococcus aureus/isolement et purification
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