Dysgerminoma: a case report on rare malignant tumor

Dysgerminoma is a malignant germ cell tumour (GCT) accounting for less than 1% of ovarian neoplasm. It is analogous to seminoma in males. It is a tumour of young age, affecting women of reproductive age group. In most of the cases, due to its clinical features of it is often, misdiagnosed as abdominal tuberculosis. It is one of the rare tumours, which have excellent response to chemotherapy and radiotherapy. It is tumour in whom, surgery followed by radiotherapy and chemotherapy gives excellent prognosis even in advanced stage. This is a rare case report of 16-year-old girl with primary amenorrhoea, abdominal mass and pleural effusion, when undergone staging laparotomy � had ovarian tumour with torsion which histopathologically came out to be, dysgerminoma.

A rare case of congenital methemoglobinemia in pregnancy

When iron in haemoglobin is replaced from Fe+2 (ferrous) to Fe+3 (ferric), it leads to formation of methemoglobin. Normal levels of methemoglobin are <1%. This is maintained by redox balance between activity of NADH methemoglobin reductase enzyme and amount of oxidised hemoglobin. When levels of methemoglobin are increased, it leads to methemoglobinemia. Methemoglobin has less affinity to bind to oxygen & results in left shift of oxygen杊emoglobin dissociation curve. As most of the cases of congenital methemoglobinemia are asymptomatic, it is often diagnosed first time during pregnancy. Here we report a case, Primigravida with 38 weeks of gestation posted for emergency LSCS i/v/o meconium-stained liquor, who had SPO2 of 84%, was clinically asymptomatic, vitally stable and with ABG, CXR, ECG and 2DECHO normal. Efforts to find out the cause of reduced oxygen saturation led to diagnosis of rare hemoglobinopathy, methemoglobinemia.