Résumé
We present the experience and figures about a screening program in South Brazil carried on in Porto Alegre, capital of the Southern Brazilian State. We present the tests performed routinely in our laboratory, the prevalence of some diseases and tests for infectious diseases to be added in the most comprehensive regional program in our country.
Sujets)
Brésil/épidémiologie , Humains , Nouveau-né , Erreurs innées du métabolisme/diagnostic , Dépistage néonatal/statistiques et données numériques , Prévalence , Toxoplasmose congénitale/diagnosticRésumé
Toxoplasmosis acquired at the end of the pregnancy can produce ocular and neurological sequelae. The detection of IgM anti-Toxoplasma gondii in dried blood spots of newborns is an important tool for early treatment and prevention. In this study we showed results of a pilot study about the prevalence of congenital toxoplasmosis in Brazil and concluded that this disease should be included in the menu of neonatal screening programs.
Sujets)
Animaux , Anticorps antiprotozoaires/sang , Brésil/épidémiologie , Humains , Nouveau-né , Dépistage néonatal , Prévalence , Toxoplasma/immunologie , Toxoplasmose congénitale/diagnosticRésumé
Screening for tyrosinemia is not routinely performed worldwide. Using a low expense thin-layer chromatography (TLC) for amino acids we detected a high frequency of transient tyrosinemia with secondary hyperphenylalaninemia in some newborns. Serum follow up showed the need to introduce adequate therapy in these babies.