Résumé
The main objective of the present study is to determine the histopathological patterns and diagnostic value of endometrial curettings in patients presenting with abnormal uterine bleeding. A prospective study. This study was conducted at Department of Pathology Liaquat University of Medical and Health Sciences Jamshoro during March 2010 to February 2011. A total of 100 cases of endometrial curettage were processed for routine staining with Haematoxylin and Eosin and slides were evaluated for histopathological diagnosis. The results showed that patient's age ranged between 40-52 years and most of the patients about 77%presented with menorrahgia. The histological findings showed normal phase [Proliferative and Secretory phase] of menstrual cycle in 52% of cases followed by simple hyperplasia without atypia 23%, chronic endometritis 13%,polyp 2%, tuberculous endometritis 2%, anovulatory cycle 1%, anovulatory cycle with chronic endometrits 1%,atrophic changes 1%, atypical complex hyperplasia 2% and malignancy in 3% of cases. The Simple hyperplasia23% and chronic endometritis 13% were the commonest pathological alteration. The accidental findings of organic lesions including polyps and malignancy in 5% cases focused the diagnostic importance of curettage in patients presenting with abnormal uterine bleeding. It is concluded that simple hyperplasia without atypia and chronic endometritis are most important causes of abnormal uterine bleeding in the perimenopausal age groups