Clinical profile and outcome of patients admitted in pediatric intensive care unit of tertiary care teaching hospital of rural North India: an observational study

Background: Aim of the study was to study the clinical profile of the patients admitted in the intensive care unit and their outcomes in the rural area of north India.Methods: A prospective observational study was conducted in the PICU of rural tertiary care centre over a period of one and half year. The severity of illness and outcome were analyzed using PRISM (Pediatric risk of mortality) and PIM2 (Pediatric index of mortality) scores.Results: A total of 500 patients with mean age of patients admitted in PICU was 8.08�56 years. The most affected system was found to be the CNS (34.80%), followed by GIT (27.40%), respiratory (17%) and various other causes (13.6%) and CVS (7.2%). There was an overall mortality of 13.40% and a survival percentage of 86.60%. Significant association was seen between various variables of PRISM and PIM2 scores. Both PRISM and PIM2 score proved with good predictors of mortality and severity of illness. However, higher value was not a sure indication of mortality. Attributed to the fact, the current scope of study leveraged into a prospective observational study with multitude of variables, multivariate analysis with random sampling was performed by SPSS 21. Significant levels were corroborated at (p<0.05) to validate mortality (outcome) based on PIM2 and PRISM scores in first place.Conclusions: The knowledge of demographic and clinical profile of the patients in a particular area and use of physiological scores can help streamline the use of limited resources in PICUs of developing countries.

Premenstrual syndrome among budding medical professionals at medical college in a metro city: a cross sectional study

Background: Premenstrual syndrome (PMS) is a group of menstrual disorder constituting various physical, emotional and behavioral symptoms occurring in the luteal phase usually a week before menstruation. It is a very common condition affecting many young girls and severity can have a negative impact on the quality of life. Our study was done to estimate the prevalence of this condition among the medical undergraduate students.Methods: This cross-sectional study was conducted at Lady Hardinge medical college, New Delhi, India among medical undergraduates after ethical clearance. A convenient sample size of 228 was taken. The participants were selected by random sampling technique and informed consent was obtained. The data was collected as per PMSS scale and analyzed by frequencies and percentages using SPSS version 21.Results: The prevalence of PMS among our enrolled participants was 100%. Majority about 61% belonged to age group of 21-25 years. About 40.8% of students had mild symptoms, 35.1% moderate, 18.0% severe and 6.1% very severe form of PMS. However, no significant difference was found in the severity between 2 age groups.Conclusions: Our study highlights 100% prevalence of PMS with varied severity of presentation. The very high prevalence of PMS among medical undergraduates calls for an urgent need to priorities the health care by creating awareness and provide necessary medical, social and psychological support to our budding professionals.

Demineralized freeze-dried bone allograft with/without i-Platelet-rich fibrin in 3 wall intrabony defects

Demineralized freeze-dried bone allograft (DFDBA) contains bone morphogenetic proteins (BMPs), hence is osteoinductive. Autologous platelet concentrates exhibit a higher quantity of growth factors. Both these biomaterials aid in bone regeneration when placed in three-wall intrabony defects. However, their efficacy when used alone and in conjugation is not clear. Aim: To assess clinical and radiographic efficacy of injectable platelet-rich fibrin (i-PRF) with microsurgical access flap in the treatment of three-wall intrabony defects in chronic periodontitis patients. Methods: Thirty sites with three-wall intrabony defects were randomly assigned to control and test group by computer generated method. The test group obtained i-PRF mixed with DFDBA while the control group received only DFDBA. Clinical parameters such as site-specific Plaque index (PI), Radiographic intrabony defect depth (IBDD), modified- Sulcular bleeding index (mSBI), Clinical attachment level (CAL), and Probing pocket depth (PPD) were measured at baseline, three and six months. Results: Intragroup comparison within the control group and test group exhibited statistically highly significant variation of mean PI, mSBI, PPD, CAL, and IBDD score from baseline to 3 months and from 3-6 months (p<0.001). However, intergroup comparison demonstrated no statistically significant variation of mean IBDD at all 3 intervals (p>0.05). Conclusion: i-PRF combined with DFDBA enhanced the radiographic and clinical parameters as opposed to DFDBA alone. The role of i-PRF is promising in its capacity for easy obtainability and increased potential to aid in regeneration

Longitudinal bond strength of a universal adhesive and chemical dentin characterization under different acid etching protocols

Abstract Objective This study aimed to analyze the longitudinal bond strength of a universal adhesive and chemically characterize the dentin substrate under different acid etching protocols. Methodology Dentin samples were etched with polyacrylic acid 25% (PAA) for 10 seconds (n=3) and phosphoric acid 32% (PA) for 15 seconds (n=3) and analyzed by Fourier transform infrared spectroscopy - attenuated total reflectance (FTIR-ATR) before and after treatment. For collagen degradation, samples (n=12) were divided into 3 groups: PAA, PA, and Deionized water (control), and analyzed by the quantity of solubilized type I collagen C-terminal cross-linked telopeptides and solubilized C-terminal peptide in relation to total protein concentration (ICTPtp and CTXtp) and by their ultimate tensile strength (UTS). For the adhesive interface analysis, dentin samples (n=72) were divided into 3 groups: PAA, PA, and Self-etch (SE), and subdivided into 2 groups: 24 h (baseline) and 1 year. The following tests were performed: microtensile bond strength (μTBS) (n=48), scanning electron microscopy (SEM) (n=12), and nanoleakage (n=12). Results The FTIR of PAA showed lower reduction of the peaks in the phosphate group when compared to PA. For ICTPtp, PA showed a significantly higher value. For CTXtp, PA and PAA groups failed to statically differ from each other. UTS was significantly lower for PA. For μTBS, storage time significantly affected bond strength. The results were unaffected by the etching protocol. For SEM, after 1 year, PA had little evidence of degradation in the upper third of the adhesive interface in comparison to the other groups. Nanoleakage showed no considerable silver impregnation after 1 year in the SE group. Conclusion The use of PAA prior to a universal adhesive (when compared to PA) represents a less aggressive type of etching to dentin. However, self-etching still seems to be the best option for universal adhesive systems that have functional monomers in their composition.

Genetic Variability, Heritability and Genetic Advance in F2 Segregating Population of Cross RNR-15048 x Dokra-Dokri in Rice (Oryza sativa L.)

The present experiment was conducted to study the variability, heritability and genetic advance in F2 segregating population derived from the cross, RNR-15048 x Dokra-Dokri, evaluated in augmented design with two checks at ICAR-IIRR, Hyderabad during the Kharif-2022. Analysis of variance revealed the presence of significant differences for all eleven traits examined, indicating the presence of genetic variation between the individuals studied. Higher values of Genotypic Coefficient of Variation (GCV) and Phenotypic Coefficient of Variation (PCV) were observed for panicle weight, number of filled grains, number of unfilled grains, total grains per panicle, and single plant yield. Least difference was observed between PCV and GCV value for almost all the traits indicating the little influence by the environment and possibility for genetic improvement of these traits through selection. The traits plant height, panicle weight, number of filled grains, number of unfilled grains, total grains per panicle, spikelet fertility, thousand grain weight and single plant yield recorded high heritability (>60%) associated with high genetic advance as percent of mean (>20) resulting in no environmental influence on the expression and selection for improvement of such characters could be worthwhile. High heritability coupled with moderate genetic advance as percent of mean was observed for panicle length propounding non-additive gene action in their inheritance suggesting heterosis breeding could be useful for improving these traits. Overall high PCV and GCV coupled with high heritability and high genetic advance as percent of mean was noticed for panicle weight, number of filled grains, number of unfilled grains, total grains per panicle, and single plant yield suggesting significant amount of variability with predominance of additive type of gene action. Hence, direct phenotypic selection.

The Future of Rice Farming: A Review of Natural and Eco-Friendly Practices

Recognizing rice as a staple for a significant global population, the review underscores the environmental challenges posed by traditional and conventional rice farming methods. It emphasizes the promise of sustainable rice cultivation, focusing on innovations like the System of Rice Intensification (SRI) and climate-friendly techniques that mitigate environmental impacts. Furthermore, it delves into the benefits of crop rotation, sustainable water management, soil health preservation through mycorrhizal associations, companion planting, and the role of precision agriculture empowered by artificial intelligence. The abstract discusses the challenges, including climate change, water scarcity, soil health, and labor shortages, and proposes prospects involving innovation, sustainable practices, policy support, and collaborative partnerships. It highlights real-world successes in eco-friendly rice farming, such as initiatives, and emphasizes the importance of empowering farmers through education and training in eco-friendly methods. Ultimately, role of eco-friendly practices in ensuring the sustainability, productivity, and food security of global rice farming.

Population Dynamics of Defoliator Pests of (Arachis hypogea L.) in Different Staggered Sowings

The present study was conducted to assess the incidence of defoliator pests of groundnut in three different staggered sowings. The experiment was laid with three treatments and seven replications which was carried out at RARS (Regional Agricultural Research Station), Palem, Nagarkurnool district, Telangana state which is having hot and dry climate. The data has been correlated with various weather parameters, including Maximum temperature, Maximum temperature, RH-I and RH-II. The variety K-6 was grown in three staggered sowings (D1: 1st Oct; D2: 15th Oct; D3: 1st Nov). There was a less population of leaf miner during D1 the correlation studies revealed that tobacco caterpillar showed a non-significant negative correlation with the Tmax ºC (r= -0.233) and a significant positive correlation with Tmin ºC (r= 0.370) and RH-? (r=0.640). whereas gram caterpillar showed a positive significant correlation to Tmax (r= 0.256) and Tmin (r= 0.097) and a negative significant correlation towards RH-? (r= -0.186) and RH-? (r= -0.501).

Study of Genetic Variability Parameters for Yield and Its Components under Normal and Late Sown Conditions in Chickpea (Cicer arietinum L.)

An investigation consisted of 50 chickpea genotypes including 4 checks viz., JG64, ICC10685, ICC4567 and NBeG47 was conducted during the rabi season of year 2022-23 at Seed Research and Technology centre, Rajendranagar, Telangana. The objective of the study was to estimate magnitude of different parameters of genetic variability for yield and its attributes. The observations were recorded for thirteen different yield and its contributing characters and the results obtained indicated that in general the phenotypic coefficient of variance was found to be higher as compared to genotypic coefficient of variance for all studied traits. High heritability along with high genetic advance (% mean) was obtained for characters like number of seeds per plant, number of filled pods per plant, seed yield per plant, number of pods per plant, number of primary branches, 100 seed weight, number of secondary branches, and plant height at normal sown conditions, which determines the presence of additive gene action for these characters and in late sown conditions the characters like number of seeds per plant, number of filled pods per plant, seed yield per plant, number of pods per plant, number of primary branches, 100 seed weight, number of secondary branches, and plant height and harvest index had shown high heritability along with high genetic advance. So, it determines the presence of additive gene action for these characters. So, that selection for these characters is beneficial in the breeding programmes.

A study on awareness regarding universal precautions among medical students of tertiary teaching hospital, Bengaluru

Background: Health care staffs are at increased risk of acquiring various infection as they are exposed to infectious agents at their workplace hence having awareness regarding Universal precautions help them protect themselves and provide better health care services. Methods: Descriptive study was conducted on 220 medical students of 5th, 7th and 8th term for a period of 2 months. Medical students were selected based on probability proportional to size sampling method. Semi-structured questionnaire was used to interview the study subjects Results: Assessment regarding awareness on Universal Precautions among Medical students was done by administering questionnaire on Universal Precautions. Awareness on Hand hygiene among medical students was 92% (195/220). 98.1% (208/220) of them had awareness regarding gloves usage, 45.6% (124/220) of them were unaware about safe needle practices. Conclusions: Medical students lack awareness regarding safe needle practices. They were aware of other aspects such as hand hygiene and gloves usage.

Influence of Weather Parameters on the Population of Sucking Pests in Castor Genotypes

Field experiment were carried out to study the seasonal incidence of leafhopper, Empoasca flavescens and thrips, Scirtothrips dorsalis and also the influence of weather parameters on the sucking pest population in five castor genotypes i.e., DCH-519, DCH-177, ICH-66, NBCH, PCH-111 during Rabi, 2020-21 at the research farm of RARS, Palem, PJTSAU, Telanagana. The pest population was recorded from 10 random plants and the incidence was observed from 48th standard meterological week and the peak population of sucking pests was observed during 6th to 8th standard week. PCH-111 and NBCH were observed to be more susceptible to sucking pests whereas DCH-519 was least susceptible. The observed pest population is correlated with weather parameters by taking the weather data from the agro meteorological observatory located at RARS, Palem. Correlation studies indicated that all the parameters except max temperature had a negative influence on thrips whereas temperature showed positive influence towards hoppers.

Preventive effect of cranberry gel on dentin submitted to erosion

Aims: Considering that Cranberry's components might inhibit dentin metalloproteinases exposed to erosive agents, the aim of this study was to evaluate in situeffect of a Cranberry gel application on dentin before an erosive challenge.Materials and methods: This crossover double-blinded study was performed in 2 phases of 5 days each, with 10 healthy volunteers who wore 2 palatal devices (1 for each phase) with 4 dentin specimens (2 specimens for each group). The groups under study were:First Phase: G1 -Erosivechallenge (Coca-cola®) over dentin without any previous treatment (1st negative control group); G2 -Erosive challenge over dentin previously treated with Cranberry gel (test group); and Second Phase: G3 -Erosive challenge over dentin previously treated with a gel without any active principle (2ndnegative control group); G4 -Erosive challenge over dentin previously treated with 0.12% Chlorhexidine gel (positive control group). Each device was immersed into the acid beverage, 3 times daily for 5 minutes during 5 days. Profilometry (µm) was used to quantify the dentin wear. Data were analyzed by Repeated Measures Analysis of Variance followed by Fisher's test (p<0.05).Results: Data (G1: 4.98 ± 1.36a; G2: 3.29 ± 1.16b; G3: 4.38 ± 1.19a; G4: 3.32 ± 1.55b) showed no statistical difference between G1 and G3. There was also no difference between G2 and G4. However, G2 and G4 presented lower wear when compared to G1 and G3, and this difference was statistically significant. Conclusion: The results of this studysuggest a significant efficacy of Cranberry gel in preventing wear of dentin subjected to dental erosion.

A study of iron status in children with cyanotic congenital heart disease

Background: Iron deficiency is a common problem in patients with cyanotic congenital heart disease (CCHD), but it is often underdiagnosed. Cyanotic patients with iron deficiency will experience higher morbidity due to symptoms of hyper viscosity. The consequences of iron deficiency anemia in cyanotic heart disease may manifest either in infancy or later. The tendency to develop metabolic acidosis and hyper-cyanotic attacks is exacerbated by relative iron deficiency anemia. This study was performed to identify the prevalence of iron deficiency in children with CCHD based on definitive tests like serum ferritin.Methods: We included 100 patients with congenital cyanotic heart diseases between 3 months to 18 years. Baseline characteristics were noted in specific proforma. Data from the blood tests were collected and analysed statistically to find out the prevalence of iron deficiency, along with tests that best predict the presence of iron deficiency. Results: Serum ferritin-based prevalence of iron deficiency in CCHD was 46%. Iron status based on haemoglobin, MCV values with the serum ferritin, and the strength of agreement were almost perfect. The strength of agreement for PCV, MCH, RDW, and peripheral smear was substantially significant. The strength of agreement for MCHC was moderate significance (Kappa value 0.41-0.60). Red cell distribution width (RDW) was an independent predictor of iron deficiency in logistic regression analysis.Conclusions: RDW seems to be a good indicator for predicting iron deficiency in children with congenital cyanotic heart diseases.

Clinical and metabolic characteristics of males with early-onset androgenetic alopecia

Background: Men with early-onset androgenetic alopecia (AGA) often have an abnormal hormonal milieu. Objective: To ascertain the clinico-phenotypic characteristics and the prevalence of hormonal and metabolic changes in men with early-onset AGA. Methods: Consecutive male patients less than 30 years of age with a Norwood-Hamilton grade ?3 AGA were recruited in this comparative cross-sectional study. After endocrine evaluation they were classified into two groups, that is, Group A consisting of subjects with an altered hormonal profile and Group B with normal hormonal profiles. The groups were assessed for differences in disease phenotype and severity (Norwood-Hamilton grade), insulin resistance and parameters of metabolic syndrome (ATP III guidelines). Results: Altered hormonal profiles were seen in 34 of the 100 subjects with AGA, while insulin resistance and metabolic syndrome were noted in 44 and 26 respectively. Altered hormonal profiles were significantly associated with insulin resistance and severe alopecia (grade 4 and above Hamilton-Norwood Scale). Insulin resistant Group A patients had a significantly higher prevalence of severe alopecia (>grade 4) (P = 0.0036). The prevalence of metabolic syndrome was similar in both groups. Limitation: The cross sectional study design was a drawback of this study. Further, a control arm without AGA was not included and the sample size of 100 was selected arbitrarily. Conclusion: An altered hormonal profile and insulin resistance was noted in a third of the males with early-onset AGA. Subjects with altered hormonal profiles had a higher prevalence of insulin resistance and were likely to have severe grades of AGA

Study to assess incidence and type of congenital heart defect in children with down syndrome presenting to tertiary care teaching hospital of Southern Rajasthan

Background: Down syndrome occurs in people of all races and economic levels. Cardiac anomalies with a prevalence of about 50% are the most common anomaly responsible for death during the 1st two years of life in children with down syndrome. Objective of the study was to Assess the incidence and type of congenital heart disease in children with down syndrome presenting to a tertiary care hospital.Methods: Hospital based descriptive study. Participants: All children (0 to 18 years) diagnosed (clinically or on karyotyping) with Down syndrome, presenting in RNT Medical College, Udaipur Each patient was evaluated with a pre-set Performa which contained detailed sociodemographic profile, maternal and clinical history including age of conception, detailed physical examination to look for features of down syndrome. Degree of Intellectual / Developmental retardation was assessed by Vineland Social Maturity Scale. 2D- echo, karyotyping was done in all patient. CBC, thyroid profile, CXR, USG- abdomen, Invertogram were done as per need.Results: Out of 57 Down syndrome children, 32(56.1%) were males and 25(43.9%) were females. Congenital heart defect was found in 35 out of 57 Down syndrome children (61.4%). Among 35 cases 82.2% had Acyanotic CHD and 17.1% had Cyanotic CHD. Ventricular Septal defect (31.4%) was the most common Congenital heart defect followed by Atrial Septal defect in 20% cases. Trisomy 21 was observed among 94.7% cases.Conclusions: More than half of children with Down syndrome have congenital heart disease, mostly Acyanotic, more specifically VSD. Early screening and diagnosis re the key to avoid irreversible hemodynamic consequences.

Clinical profile and etiology of children presenting with prolonged fever in tertiary care centre of Southern Rajasthan

Background: Fever is the most common complain of a child presenting to a health care setting. A prolonged fever however, is an intriguing challenge for clinicians and remains overly medicated and inappropriately worked up, provided a systemic approach is not followed. Our study aims to find the etiologic diagnosis in these cases of prolonged fever.

Methods: The present study was conducted in a tertiary care hospital in southern Rajasthan over a period of 12 months from November 2021 to October 2022. Our descriptive, observational study enrolled 150 children who were prospectively followed during their stay in hospital. Each patient was subjected to a set of mandatory investigations followed by other investigations as per the diagnostic clues. Patients were monitored closely during their course of stay until discharge, at which the final diagnosis was charted.

Results: A diagnosis could be reached for 138 patients (92%) and in 12 patients (8%), the cause of fever remained undiagnosed until discharge/death. Out of the 138 patients diagnosed, 118 patients (85.5%, 78.6% overall) had an infection as the cause of fever and 20 cases (14.49%,13.3% overall) had a non-infective etiology.

Conclusions: Infections are the most common cause of prolonged fever in pediatric population - tuberculosis being the most frequent infection. Hematological malignancies were found as an emerging cause of prolonged fever in our study.

Ultrasound assessment of foetal head-perineum distance prior to induction of labour as a predictor of successful vaginal delivery: a prospective study from a tertiary care hospital of Rajasthan

Background: Induction of labor (IOL) is one of the most frequent obstetric procedures require for various obstetrics indications in 13-20% of term. Traditionally success of induction has been determined by Bishop score, but this score is observer based and significant inter observer disagreements have been noted. Ultrasound can help obstetricians in counselling patients before induction of labour and explain the probability of successful induction. So in this study we did ultrasound assessment of foetal head-perineum distance prior to induction of labour as a predictor of successful vaginal delivery.Methods: All eligible women who are planned for induction of labour will undergo ultrasound assessment of foetal head–perineum distance prior to induction of labour. Transvaginal ultrasound will also be performed using ultrasound probe to measure cervical length. After the scans, prevaginal examination will be performed to assess the various components of modified Bishop score (min 0, max 10). If cervix is found unfavourable, induction of labour will be done. If patient did not go into active labour, then induction will be considered unsuccessful) or else oxytocin drip in cases where cervix is found favourable. The patients will be followed up till delivery.Results: Out of 125 patients enrolled for the study, 101 women delivered successfully vaginally and 24 had to undergo caesarean delivery. Of these 24 cases of caesarean delivery, 11 cases were excluded as the operative procedure was performed for indication not related to unsuccessful induction such as occurrence of foetal distress in labour, thick meconium-stained liquor with unfavourable cervix. The final analysis was performed from 114 subjects (101 vaginal births and 13 caesarean births).Conclusions: Transperineal fetal head–perineum distance is less painful as less time consuming and less acceptable by patients compare to Transvaginal measurement of cervical length and painful digital examination for bishop score.

Predictive value of admission and intrapartum cardiotocography in normal and high risk antenatal women

Background: Cardiotocography is the most common method for assessing fetal health and reveals brain oxygenation. This study is done for admission and intrapartum cardiotocography in high- and low-risk pregnancies and its correlation with neonatal outcome.Methods: All high-risk and normal antenatal women with more than 34 weeks of pregnancy and vertex presentation who came to the labor room were included in the study. 200 cases were taken, 100 were in the "high risk group," and the remaining 100 were in the "low risk group." On admission CTG and intrapartum CTG tracing were taken after written and informed consent, neonatal outcomes were observed, and adverse neonatal outcomes were noted.Results: Admission CTG results were unsatisfactory for 9% of women in the high-risk group and none in the low-risk group. Intrapartum NST was non reassuring in 51% of high-risk women and 6% of the low-risk group. Of the total number of neonates admitted to the NICU, 14 were from the low-risk group, while 50 were from the high-risk group.Conclusions: On admission NST in both low and high-risk women, the absence of category III NST predicted the absence of an adverse neonatal outcome most accurately. Even during labor in both high-risk and low-risk women, the absence of category III reassured the fetal well-being most precisely.

FORMULATION DEVELOPMENT AND EVALUATION OF SOLID SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM OF AZELNIDIPINE

This study aimed to develop a self-micro emulsifying drug delivery system (SMEDDS) for poorly soluble azelnidipine using Capryol 90 as the oil, Tween 80 as the surfactant, and transcutol-HP as the co-surfactant. A factorial design was used to optimize the formulation, and Neusilin UFL2 was used as an adsorbent to convert the liquid SMEDDS to solid SMEDDS. The optimized formulation had a particle size of 80.5nm, a transmittance of 98.2%, a zeta potential of -3.1 mV, and a polydispersibility index of 0.226. The solid SMEDDS tablet exhibited improved drug release (99.4% in 60 minutes) compared to the marketed tablet (67.09.75%) and pure drug (26.17%). This study demonstrates the potential of the SMEDDS approach to enhance the solubility and in-vitro drug release of poorly soluble drugs such as azelnidipine.

Vermicomposting: An effective method to treat waste sludge

The environment is seriously threatened as a result of the world’s rising volume of solid waste generation. Biodegradable pollutants will impart an unpleasant smell and create an unsanitary situation if suitable precautions are not implemented. Vermicomposting can be suitable option for handling solid waste in an eco-friendly manner. The review aims to assess the viability of using vermitechnology to extract nutrients from organic sludge and return them to the environment. This review is focused on earthworms and their mechanisms in vermicomposting process, various affecting factors and physical-microbial properties of vermicast

Renal biopsy - indication and its implications in management of children admitted at a tertiary care hospital, Mangalore

Background: Percutaneous renal biopsy is an established diagnostic tool for identification of renal pathology required for diagnosis, treatment, and prognostication. The present study was conducted to know the common indications and histopathological findings of renal biopsy, impact of biopsy report on treatment, and complications of procedure.Methods: This was a retrospective observational study conducted in the paediatric ward of a tertiary care level hospital. Indications of renal biopsy as suggested by medical records were noted down. Any treatment changes happened after final histopathological report were recorded. Statistical analysis was made using statistical package for the social sciences (SPSS) version 20.0 (IBM, NY).Results: The mean age of patients at which biopsy was done was 9.83±5.31 years. Most common indications of renal biopsy were nephritic onset nephrotic syndrome (34.8%), steroid-resistant nephrotic syndrome (21.7%), steroid-dependent nephrotic syndrome requiring calcineurin inhibitors (CNI) (17.4%), lupus nephritis (8.7%), nephrotic syndrome with later age of onset (8.7%), acute kidney injury (AKI) stage 3 (4.3%) and for evidence of calcineurin inhibitor toxicity (4.3%). Focal segmental glomerulosclerosis (26.1%), minimal change disease (21.7%) and membranoproliferative glomerulonephrosis (17.4%) were the most common histopathological findings.Conclusions: This study reiterates the fact that renal biopsy is one of the decisive and diagnostic procedures and has good prognostic value in further management of medical renal disease.