1.
Braz. j. med. biol. res
;
23(8): 743-6, 1990. ilus
Article
Dans Anglais
| LILACS
| ID: lil-92334
Résumé
The time course of degeneration of retinal ganglion cells was studied in vitro. We used the retinae of newborn hooded rats retrogredely labeled with horseradish peroxidase injected bilaterally into the conditined medium either from aggregates or from explants of retinal cells on the survival of the ganglion cells. Both conditioned media approximately doubled the survival of ganglion cells after 48-72 h in culture. Our data are consistent with the hypotesis that retinal cells produce soluble trophic factors that influence ganglion cell survival