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Rev. Soc. Bras. Med. Trop ; 51(4): 542-545, July-Aug. 2018. tab
Article Dans Anglais | LILACS | ID: biblio-1041473

Résumé

Abstract INTRODUCTION This study aims to evaluate the antifungal susceptibility of different species of Candida isolated from diabetic patients against eight antifungal agents. METHODS Susceptibility testing of 111 clinical isolates of Candida species was performed against 8 antifungals using the M27-A3 protocol of the Clinical and Laboratory Standards Institute (CLSI). RESULTS Voriconazole, lanoconazole, and caspofungin showed the highest in vitro activity against all the isolates of C. albicans. Resistance against the tested antifungals was only observed in the C. albicans isolates. CONCLUSIONS Our finding revealed that resistance against amphotericin B, itraconazole, ketoconazole, posaconazole, and fluconazole can be observed in C. albicans.


Sujets)
Humains , Mâle , Femelle , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Candida/effets des médicaments et des substances chimiques , Diabète/microbiologie , Antifongiques/pharmacologie , Candida/isolement et purification , Candida/classification , Tests de sensibilité microbienne/méthodes , Adulte d'âge moyen
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