Predictive value in computed tomography in diagnosing stage of renal tumors

Objective: To determine the frequency of true positive cases in staging of renal cell carcinoma on computed tomography[CT] tacking histopathology as gold standard

Methods: 75 patients diagnosed as RCC on CT underwent nepherectomies and histopathological / radiological staging were compared

Results: The overall sensitivity of CT for diagnosing RCC was 93.33%. For T1a 100%, for T1b 51.7%, for T2 80%, for T3a 75%, for T3b 2% and for T4 100%. The sensitivity for N1 and N2 is 66.67% and 80.2% respectively. CTshowed higher stage in 43.3% cases

Conclusion: Computed tomography is still a good diagnostic modality for pre-operative staging of RCC and planning of surgery

Tuberous sclerosis with bilateral angiomyolipomas

A case of a 30-year-old female with tuberous sclerosis, a genetic, rare, variably expressed disease is described in the present case report. Clinical symptoms were unexplained fever, pain in lumber areas and gross hematuria. Computed tomography scan of the abdomen revealed enlarged, heterogeneous kidneys, with low density tumors corresponding to angiomyolipomas. Computed tomography scan of the chest showed bilateral, diffuse, small thin-walled cysts in the lungs characteristic for pulmonary lymphangioleiomyomatosis. CT scan of the brain revealed subependymal calcifications. These three diagnostic features are rarely exhibited in a single patient. Bilateral renal angiomyolipomas and pulmonary lymphangioleiomyomatosis are some presentations of tuberous sclerosis and the coexistence of both conditions may cause devastating morbidity and mortality